Thuốc Thiola EC (Oral)

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Thuốc Thiola EC (Oral)
Thuốc Thiola EC (Oral)

Holevn Health share articles about :Thuốc Thiola EC (Oral)  , side effects – dosage , Thuốc Thiola EC (Oral) what disease treatment.Other noted issues. Please refer to the details below.

Generic Name: tiopronin (Oral route)

tye-oh-PROE-nin

Medically reviewed by Holevn.org. Last updated on Oct 16, 2019.

Commonly used brand name(s)

In the U.S.

  • Thiola
  • Thiola EC

Available Dosage Forms:

  • Tablet, Delayed Release
  • Tablet

Therapeutic Class: Renal-Urologic Agent

Uses for Thiola EC

Tiopronin is used together with high fluid intake, alkali, and diet to prevent kidney stones in patients with severe homozygous cystinuria (too much cystine in the urine). This medicine works by removing the extra cystine from the body.

This medicine is available only with your doctor’s prescription.

Before using Thiola EC

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Use in children weighing less than 20 kilograms (kg) or who cannot swallow tablets is not recommended. Safety and efficacy have not been established.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tiopronin in the elderly. However, elderly patients are more likely to have age-related kidney problems, which may require caution and an adjustment in the dose for patients receiving this medicine.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Ethanol

Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Toxicity to d-penicillamine, severe, history of—Use with caution. May increase the risk for unwanted effects.
  • Kidney disease—Use with caution. The effects may be increased because of the slower removal of the medicine from the body.

Proper use of Thiola EC

This section provides information on the proper use of a number of products that contain tiopronin. It may not be specific to Thiola EC. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Take the tablet at least 1 hour before or 2 hours after meals. The delayed-release tablet may be taken with or without food.

Swallow the delayed-release tablet whole. Do not crush, break, or chew it.

Drink extra fluids so you will pass more urine while you are using this medicine. This may help prevent kidney problems.

Do not drink alcohol 2 hours before and 3 hours after using Thiola® EC.

It is important that you follow any special instructions from your doctor, such as following a low-methionine diet. Methionine is found in animal proteins such as milk, eggs, cheese, and fish. Also, make certain your health care professional knows if you are on any special diet, such as a low-sodium or low-sugar diet. If you have any questions about this, check with your doctor.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage forms (delayed-release tablets, tablets):
    • To prevent kidney stones:
      • Adults—At first, 800 milligrams (mg) divided into 3 doses, given at the same times each day. Your doctor may change your dose as needed.
      • Children weighing 20 kilograms (kg) or more—Dose is based on body weight and must be determined by your doctor. At first, 15 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses. Your doctor may change your dose as needed. However, the dose is usually not more than 50 mg per kg per day.
      • Children weighing less than 20 kg—Use is not recommended.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using Thiola EC

It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. Urine tests are needed to check for any unwanted effects.

Check with your doctor right away if you have bloody urine, a decrease in frequency or amount of urine, an increase in blood pressure, increased thirst, loss of appetite, lower back or side pain, nausea, swelling of the face, fingers, or lower legs, troubled breathing, unusual tiredness or weakness, vomiting, or weight gain. These could be symptoms of a serious kidney problem.

This medicine may cause serious allergic reactions. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.

Thiola EC side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  • Bloating or swelling of the face, arms, hands, lower legs, or feet
  • cloudy urine
  • hives, itching, skin rash
  • pale skin
  • rapid weight gain
  • tingling of the hands or feet
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • unusual weight gain or loss

Incidence not known

  • Bloody urine
  • blurred vision
  • chest pain
  • confusion
  • decreased frequency or amount of urine
  • dilated neck veins
  • dizziness
  • dry mouth
  • extreme tiredness or weakness
  • fainting
  • headache
  • increase in heart rate
  • increased thirst
  • irregular breathing
  • irregular heartbeat
  • lightheadedness
  • loss of appetite
  • lower back or side pain
  • nausea
  • nervousness
  • pounding in the ears
  • rapid breathing
  • slow or fast heartbeat
  • sunken eyes
  • tightness in the chest
  • troubled breathing
  • vomiting
  • wrinkled skin
  • yellow skin or eyes

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bruising
  • cough
  • decreased interest in sexual intercourse
  • diarrhea
  • difficulty in moving
  • fever
  • inability to have or keep an erection
  • large, flat, blue or purplish patches in the skin
  • loss in sexual ability, desire, drive, or performance
  • mouth sores
  • muscle pain or stiffness
  • nausea
  • pain in the joints
  • skin wrinkling
  • stomach pain

Incidence not known

  • Arm, back, neck, or leg pain
  • burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feelings
  • change in or loss of taste
  • chapped lips
  • dry skin
  • excess air or gas in the stomach or bowels
  • feeling of constant movement of self or surroundings
  • full feeling
  • heartburn
  • increased sweating
  • increased weight
  • lack or loss of strength
  • passing gas
  • sensation of spinning
  • stomach discomfort

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Thiola EC (Oral)  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/thiola-ec.html

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