Holevn Health share articles about :Thuốc Taliglucerase alfa (Intravenous) , side effects – dosage , Thuốc Taliglucerase alfa (Intravenous) what disease treatment.Other noted issues. Please refer to the details below.
Medically reviewed by Holevn.org. Last updated on Nov 17, 2019.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
- Powder for Solution
Therapeutic Class: Enzyme Replacement
Pharmacologic Class: Enzyme
Uses for taliglucerase alfa
Taliglucerase alfa injection is used for the long-term treatment of type 1 Gaucher disease. This disease is caused by the lack of a certain enzyme in the body called glucocerebrosidase. This enzyme is necessary for the body to use fats correctly, and fats will build up in certain areas of the body if the enzyme is not present. Taliglucerase alfa replaces the missing enzyme to help the body process fats.
Taliglucerase alfa is to be given only by or under the direct supervision of a doctor.
Before using taliglucerase alfa
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For taliglucerase alfa, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to taliglucerase alfa or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of taliglucerase alfa injection in children younger than 4 years of age. Safety and efficacy have not been established.
Although appropriate studies on the relationship of age to the effects of taliglucerase alfa injection have not been performed in the geriatric population, no geriatric-specific problems have been documented to date.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Proper use of taliglucerase alfa
A nurse or other trained health professional will give you or your child taliglucerase alfa in a hospital or clinic. Taliglucerase alfa is given through a needle placed in one of your veins.
Taliglucerase alfa is usually given every other week. Each treatment usually takes 60 to 120 minutes.
You or your child may also receive medicines to help prevent unwanted effects from the injection.
Precautions while using taliglucerase alfa
It is very important that your doctor check you closely while you or your child are receiving the medicine. This is to make sure that taliglucerase alfa is working properly and does not cause unwanted effects.
Taliglucerase alfa may cause serious allergic reactions, including anaphylaxis. Anaphylaxis requires immediate medical attention. The most serious signs of this reaction are very fast or irregular breathing, gasping for breath, wheezing, or fainting. Other signs may include changes in color of the skin of the face, very fast but irregular heartbeat or pulse, hive-like swellings on the skin, and puffiness or swellings of the eyelids or around the eyes. If these side effects occur, get emergency help at once.
Taliglucerase alfa side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
- Chest tightness
- feeling of warmth
- hives or welts, itching, or skin rash
- irritation in the throat
- large, hive-like swelling on face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
- nausea or vomiting
- redness of the face, neck, arms, and occasionally, upper chest
- redness of the skin
- Blurred vision
- difficulty with swallowing
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast heartbeat
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- unusual tiredness or weakness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- Abdominal or stomach pain
- difficulty with moving
- feeling of warmth
- muscle pain or stiffness
- pain in the joints
Incidence not known
- Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Seek emergency medical attention or call 115
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Reference from: https://www.drugs.com/cons/taliglucerase-alfa-intravenous.html