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tag-RAX-oh-fusp – erzs
Capillary Leak Syndrome (CLS) which may be life-threatening or fatal, can occur in patients receiving tagraxofusp-erzs. Monitor for signs and symptoms of CLS and take actions as recommended
Medically reviewed by Holevn.org. Last updated on Jan 8, 2020.
Commonly used brand name(s)
In the U.S.
Available Dosage Forms:
Therapeutic Class: Antineoplastic Agent
Uses for tagraxofusp-erzs
Tagraxofusp-erzs injection is used to treat blastic plasmacytoid dendritic cell neoplasm (BPDCN).
Tagraxofusp-erzs is to be given only by or under the direct supervision of your doctor.
Before using tagraxofusp-erzs
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For tagraxofusp-erzs, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to tagraxofusp-erzs or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of tagraxofusp-erzs injection in children 2 years of age and older. Safety and efficacy have been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tagraxofusp-erzs injection in the elderly. However, elderly patients are more likely to have unwanted effects (eg, confusion, mental problems, dementia, encephalopathy), which may require caution in patients receiving tagraxofusp-erzs.
There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.
Interactions with medicines
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of tagraxofusp-erzs. Make sure you tell your doctor if you have any other medical problems, especially:
- Heart problems—Use with caution. May cause side effects to become worse.
- Liver problems—Use with caution. May make this condition worse.
Proper use of tagraxofusp-erzs
A nurse or other trained health professional will give you tagraxofusp-erzs in a medical facility. It is given through a needle placed into one of your veins. Tagraxofusp-erzs must be given slowly, so the needle will have to stay in place for at least 15 minutes.
Your doctor may also want you to stay for at least 4 hours to check for unwanted effects.
You may receive other medicines (eg, allergy medicine, fever medicine, steroid, stomach medicine) about 60 minutes before each infusion to prevent unwanted effects.
Precautions while using tagraxofusp-erzs
It is very important that your doctor check your or your child’s progress at regular visits to make sure tagraxofusp-erzs is working properly. Blood and urine tests may be needed to check for unwanted effects.
Tagraxofusp-erzs may cause a condition called capillary leak syndrome. It can cause fluid to leak from the blood vessels into your body’s tissues. Call your doctor right away if you are urinating less often, or have swelling or puffiness, trouble breathing, feeling of fullness, dizziness, or feeling faint. You may also need to weigh yourself daily.
Tagraxofusp-erzs may cause serious allergic reactions, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after receiving tagraxofusp-erzs.
Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Tagraxofusp-erzs side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
- Black, tarry stools
- bloating or swelling of the face, arms, hands, lower legs, or feet
- bloody or cloudy urine
- blurred vision
- decrease or increase in the amount of urine
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- fast, pounding, or irregular heartbeat or pulse
- itching skin
- lower back or side pain
- painful or difficult urination
- pale skin
- pounding in the ears
- rapid weight gain
- slow heartbeat
- small red or purple spots on the skin
- sore throat
- stomach pain
- tightness in the chest
- tingling of the hands or feet
- troubled breathing
- ulcers, sores, or white spots in the mouth
- unusual bleeding or bruising
- unusual tiredness or weakness
- unusual weight gain or loss
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
- arm, back, or leg pain
- decreased appetite
- mouth or throat pain
- trouble sleeping
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Seek emergency medical attention or call 115
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The content of Holevn is solely for the purpose of providing information about Thuốc Tagraxofusp-erzs (Intravenous) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/cons/tagraxofusp-erzs-intravenous.html