Holevn Health share articles about :Thuốc Symtuza , side effects – dosage , Thuốc Symtuza what disease treatment.Other noted issues. Please refer to the details below.
Generic Name: cobicistat, darunavir, emtricitabine, and tenofovir alafenamide (koe BIK i stat, dar UE na vir, EM trye SYE ta been, and ten OF oh vir)
Medically reviewed by Holevn.org. Last updated on Oct 18, 2018.
What is Symtuza?
Symtuza contains a combination of cobicistat, darunavir, emtricitabine, and tenofovir alafenamide. Cobicistat reduces the action of enzymes in your liver that break down certain antiviral medicines. This allows the antiviral medicines to be used more safely and effectively at lower doses.
Darunavir, emtricitabine and tenofovir are antiviral medicines that prevent human immunodeficiency virus (HIV) from multiplying in your body. HIV can cause acquired immunodeficiency syndrome (AIDS).
Symtuza is a used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS).
Symtuza is not a cure for HIV or AIDS.
Symtuza can cause serious liver problems. Call your doctor if you have upper stomach pain, loss of appetite, vomiting, dark urine, or yellowing of the skin or eyes.
Stop taking Symtuza and call your doctor right away if you have a severe skin reaction: fever, burning or redness in your eyes, mouth sores, or a skin rash that spreads and causes blistering and peeling.
If you’ve ever had hepatitis B, it may become active or get worse after you stop using Symtuza. You may need frequent liver function tests for several months.
Before taking this medicine
You should not use Symtuza if you are allergic to cobicistat, darunavir, emtricitabine, or tenofovir.
Some medicines can cause unwanted or dangerous effects when used with darunavir. Your doctor may change your treatment plan if you also use:
colchicine (in people with liver or kidney disease);
elbasvir and grazoprevir;
lovastatin or simvastatin;
sildenafil (Revatio, for pulmonary arterial hypertension);
St. John’s wort;
triazolam or oral midazolam;
ergot medicines – dihydroergotamine, ergotamine, methylergonovine; or
seizure medicine – carbamazepine, phenytoin, phenobarbital.
To make sure Symtuza is safe for you, tell your doctor if you have ever had:
liver disease (especially cirrhosis, or hepatitis B or C);
an allergy to sulfa drugs; or
a bleeding disorder such as hemophilia.
You should not use Symtuza if you are pregnant. This medicine may be less effective if you take it while you are pregnant. Tell your doctor if you become pregnant. HIV can be passed to your baby if the virus is not controlled during pregnancy. Your name may be listed on a registry to track any effects of antiviral medicine on the baby.
Women with HIV or AIDS should not breast feed a baby. Even if your baby is born without HIV, the virus may be passed to the baby in your breast milk.
How should I take Symtuza?
Take Symtuza exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.
Always take this medicine with food.
If you cannot swallow a Symtuza tablet whole, you may break the tablet in half. Take both halves right away.
Use all HIV medications as directed and read all medication guides you receive. Do not change your dose or dosing schedule without your doctor’s advice. Every person with HIV should remain under the care of a doctor.
Store at room temperature away from moisture and heat.
Keep the tablets in their original container, along with the packet or canister of moisture-absorbing preservative.
If you’ve ever had hepatitis B, this virus may become active or get worse in the months after you stop using Symtuza. You may need frequent liver function tests while using this medicine and for several months after your last dose.
Symtuza dosing information
Usual Adult Dose for HIV Infection:
1 tablet orally once a day
-This drug is not recommended during pregnancy due to considerably lower exposures of darunavir and cobicistat during pregnancy.
-This drug should not be started in pregnant women; patients who become pregnant during therapy with this drug should be switched to an alternative regimen.
Use: As a complete regimen for the treatment of HIV-1 infection in patients with no prior antiretroviral treatment history or in patients virologically-suppressed (HIV-1 RNA less than 50 copies/mL) on a stable antiretroviral regimen for at least 6 months who have no known substitutions associated with resistance to darunavir or tenofovir
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
Get your prescription refilled before you run out of medicine completely.
What happens if I overdose?
Seek emergency medical attention or call 115.
What should I avoid while taking Symtuza?
Using Symtuza will not prevent your disease from spreading. Do not have unprotected sex or share razors or toothbrushes. Talk with your doctor about safe ways to prevent HIV transmission during sex. Sharing drug or medicine needles is never safe, even for a healthy person.
Symtuza side effects
Get emergency medical help if you have signs of an allergic reaction to Symtuza (hives, difficult breathing, swelling in your face or throat) or a severe skin reaction (fever, sore throat, burning eyes, skin pain, red or purple skin rash with blistering and peeling).
Call your doctor at once if you have:
increased thirst, increased urination;
little or no urination;
lactic acidosis – unusual muscle pain, trouble breathing, stomach pain, vomiting, irregular heart rate, dizziness, feeling cold, or feeling very weak or tired; or
liver problems – swelling around your midsection, right-sided upper stomach pain, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Symtuza affects your immune system, which may cause certain side effects (even weeks or months after you’ve taken this medicine). Tell your doctor if you have:
signs of a new infection – fever, night sweats, swollen glands, cold sores, cough, wheezing, diarrhea, weight loss;
trouble speaking or swallowing, problems with balance or eye movement, weakness or prickly feeling; or
swelling in your neck or throat (enlarged thyroid), menstrual changes, impotence.
Common Symtuza side effects may include:
nausea, upset stomach, diarrhea, gas;
headache, feeling tired;
changes in the shape or location of body fat (especially in your arms, legs, face, neck, breasts, and waist).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Symtuza?
Other drugs may affect Symtuza, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Symtuza only for the indication prescribed.
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The content of Holevn is solely for the purpose of providing information about Thuốc Symtuza and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/symtuza.html