Thuốc Symbicort 200 Turbuhaler (Inhalation)

29/03/2020

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Holevn Health share articles about :Thuốc Symbicort 200 Turbuhaler (Inhalation) , side effects – dosage , Thuốc Symbicort 200 Turbuhaler (Inhalation) what disease treatment.Other noted issues. Please refer to the details below.

Generic Name: budesonide and formoterol (Inhalation route)

bue-DES-oh-nide, for-MOE-ter-ol FUE-ma-rate

Medically reviewed by Holevn.org. Last updated on Nov 29, 2019.

Commonly used brand name(s)

In the U.S.

Symbicort

In Canada

Symbicort 100 Turbuhaler
Symbicort 200 Turbuhaler

Available Dosage Forms:

Aerosol Liquid

Therapeutic Class: Antiasthma, Anti-Inflammatory/Bronchodilator Combination

Pharmacologic Class: Adrenal Glucocorticoid

Uses for Symbicort 200 Turbuhaler

Budesonide and formoterol is a combination of two medicines that are used to help control the symptoms of asthma and improve lung function. It is used when a patient’s asthma has not been controlled sufficiently on other asthma medicines, or when a patient’s condition is so severe that more than one medicine is needed every day. This medicine will not relieve an asthma attack that has already started.

This medicine is also used to treat air flow blockage and reduce the worsening of chronic obstructive pulmonary disease (COPD). This includes chronic bronchitis and emphysema.

Inhaled budesonide belongs to the family of medicines known as corticosteroids (cortisone-like medicines). It works by preventing inflammation (swelling) in the lungs that causes an asthma attack.

Inhaled formoterol belongs to the family of medicines known as bronchodilators. It works by helping the muscles around the airways in your lungs stay relaxed to prevent asthma symptoms, such as wheezing and shortness of breath. This increases the flow of air through the bronchial tubes.

This medicine is available only with your doctor’s prescription.

Before using Symbicort 200 Turbuhaler

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of budesonide and formoterol combination in children 6 years of age and older. However, safety and efficacy have not been established in children younger than 6 years of age. .

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of budesonide and formoterol combination in the elderly. However, elderly patients with heart problems may require special caution when receiving budesonide and formoterol combination.

Pregnancy

Pregnancy Category	Explanation
All Trimesters	C	Animal studies have shown an adverse effect and there are no adequate studies in pregnant women OR no animal studies have been conducted and there are no adequate studies in pregnant women.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Amisulpride
Bepridil
Cisapride
Desmopressin
Dronedarone
Mesoridazine
Pimozide
Piperaquine
Saquinavir
Sparfloxacin
Terfenadine
Thioridazine
Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aceclofenac
Acemetacin
Amiodarone
Amtolmetin Guacil
Anagrelide
Aripiprazole
Aripiprazole Lauroxil
Balofloxacin
Bemiparin
Besifloxacin
Boceprevir
Bromfenac
Bufexamac
Buprenorphine
Bupropion
Buserelin
Celecoxib
Ceritinib
Choline Salicylate
Ciprofloxacin
Clofazimine
Clonixin
Clozapine
Cobicistat
Conivaptan
Crizotinib
Dabrafenib
Darunavir
Dasatinib
Degarelix
Delamanid
Deslorelin
Deutetrabenazine
Dexibuprofen
Dexketoprofen
Diclofenac
Diflunisal
Dipyrone
Domperidone
Donepezil
Droxicam
Duvelisib
Efavirenz
Encorafenib
Enoxacin
Entrectinib
Escitalopram
Etodolac
Etofenamate
Etoricoxib
Felbinac
Fenoprofen
Fepradinol
Feprazone
Fingolimod
Fleroxacin
Floctafenine
Fluconazole
Flufenamic Acid
Flumequine
Fluoxetine
Flurbiprofen
Foscarnet
Fosnetupitant
Gatifloxacin
Gemifloxacin
Glasdegib
Gonadorelin
Goserelin
Histrelin
Hydroxychloroquine
Hydroxyzine
Ibuprofen
Idelalisib
Indomethacin
Inotuzumab Ozogamicin
Ivabradine
Ivosidenib
Ketoconazole
Ketoprofen
Ketorolac
Larotrectinib
Lefamulin
Lenvatinib
Leuprolide
Levofloxacin
Lofexidine
Lomefloxacin
Lorlatinib
Lornoxicam
Loxoprofen
Lumacaftor
Lumiracoxib
Macimorelin
Meclofenamate
Mefenamic Acid
Meloxicam
Methacholine
Methadone
Metronidazole
Morniflumate
Moxifloxacin
Nabumetone
Nadifloxacin
Nadroparin
Nafarelin
Naproxen
Nepafenac
Netupitant
Niflumic Acid
Nilotinib
Nimesulide
Nimesulide Beta Cyclodextrin
Norfloxacin
Ofloxacin
Osimertinib
Oxaprozin
Oxyphenbutazone
Panobinostat
Parecoxib
Pasireotide
Pazufloxacin
Pefloxacin
Phenylbutazone
Piketoprofen
Pimavanserin
Piroxicam
Pitolisant
Posaconazole
Pranoprofen
Proglumetacin
Propyphenazone
Proquazone
Prulifloxacin
Quetiapine
Ribociclib
Ritonavir
Rofecoxib
Rufloxacin
Salicylic Acid
Salsalate
Sargramostim
Sertraline
Siponimod
Sodium Salicylate
Sotalol
Sparfloxacin
Sulindac
Sulpiride
Tacrolimus
Telaprevir
Tenoxicam
Tiaprofenic Acid
Tolfenamic Acid
Tolmetin
Tosufloxacin
Trazodone
Triclabendazole
Triptorelin
Valdecoxib
Vemurafenib
Vinflunine
Zuclopenthixol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Auranofin
Erythromycin
Ketoconazole

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper use of Symbicort 200 Turbuhaler

This section provides information on the proper use of a number of products that contain budesonide and formoterol. It may not be specific to Symbicort 200 Turbuhaler. Please read with care.

Inhaled fluticasone and salmeterol is used to prevent asthma attacks and treat chronic obstructive pulmonary disease (COPD). It is not used to relieve an asthma attack that has already started. For relief of an asthma attack that has already started, you should use another medicine. If you do not have another medicine to use for an attack or if you have any questions about this, check with your doctor.

This medicine is used with a special inhaler and usually comes with a patient information leaflet or patient instructions. Read the directions carefully before using this medicine. If you do not understand the directions or you are not sure how to use the inhaler, ask your doctor or pharmacist to show you what to do. Also, ask your doctor to check regularly how you use the inhaler to make sure you are using it properly.

Use this medicine only as directed by your doctor. Do not use more of it and do not use it more often than your doctor ordered. Also, do not stop using this medicine without telling your doctor first. To do so may increase the chance of side effects. The full benefit of this medicine may take 1 to 2 weeks or longer to achieve.

In order for this medicine to help prevent asthma attacks, it must be used every day in regularly spaced doses, as ordered by your doctor.

When you use the inhaler for the first time, or if you have not used it for 7 days or longer, or if the inhaler has been dropped, it may not deliver the right amount of medicine with the first inhalation. Therefore, before using the inhaler, prime it by spraying the medicine 2 times into the air away from the face, and shaking it well for 5 seconds before each spray.

How to use this medicine:

Take the inhaler out of the moisture-protective foil pouch before you use it for the first time.
Do not use the inhaler for this medicine with any other medicine.
Prime the inhaler before use by shaking the inhaler well for 5 seconds and then releasing a test spray. Once again, shake the inhaler and release a second test spray.
Breathe out to the end of a normal breath (exhale). Do not breathe into the inhaler.
Put the mouthpiece fully into your mouth and close your lips around it. Do not block the mouthpiece with your teeth or tongue.
While pressing down firmly and fully on the grey top of the inhaler, breathe in through your mouth as deeply as you can until you have taken a full deep breath.
Hold your breath and remove the mouthpiece from your mouth. Continue holding your breath for as long as you can up to 10 seconds before breathing out slowly. This gives the medicine time to settle in your airways and lungs.
Release your finger from the grey top and then turn your head away from the inhaler. Breathe out slowly to the end of a normal breath. Do not breathe into the inhaler.
Shake the inhaler again for 5 seconds and take the second inhalation following exactly the same steps you used for the first inhalation.
Replace the mouthpiece cover after using the medicine.
Gargle and rinse your mouth with water after each dose. This will help prevent hoarseness, throat irritation, and infection in the mouth. Do not swallow the water after rinsing.

The dose counter at the top of the inhaler will turn yellow when the inhaler has 20 or fewer doses left. Throw the inhaler when it reaches 0, or if it has been 3 months since you last opened the foil pouch.

Clean the inhaler every 7 days by wiping the mouthpiece with a dry cloth. Do not put the inhaler into water or try to take it apart. However, you must use a new inhaler with each refill of your medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For inhalation dosage form (aerosol):
- For preventing an asthma attack:
  - Adults and children 12 years of age and older—2 inhalations in the morning and another 2 inhalations in the evening. Each inhalation contains 80 or 160 micrograms (mcg) of budesonide and 4.5 mcg of formoterol.
  - Children 6 to 11 years of age—2 inhalations in the morning and another 2 inhalations in the evening. Each inhalation contains 80 mcg of budesonide and 4.5 mcg of formoterol.
  - Children younger than 6 years of age—Use and dose must be determined by your child’s doctor.
- For treatment and prevention of worsening attacks of COPD:
  - Adults—2 inhalations in the morning and another 2 inhalations in the evening. Each inhalation contains 160 micrograms (mcg) of budesonide and 4.5 mcg of formoterol.
  - Children—Not used for COPD in this age group.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the canister at room temperature, away from heat and direct light. Do not freeze. Do not keep this medicine inside a car where it could be exposed to extreme heat or cold. Do not poke holes in the canister or throw it into a fire, even if the canister is empty.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the inhaler with the mouthpiece down.

Precautions while using Symbicort 200 Turbuhaler

It is very important that your doctor check the progress of you or your child at regular visits to make sure that this medicine is working properly and to check for any unwanted effects. You may need to have your eyes checked at regular visits. Be sure to keep all appointments.

Although this medicine decreases the number of asthma episodes, it may increase the chances of a severe asthma attack when they do occur. Be sure to read about these risks in the patient information leaflet and talk to your doctor about any questions or concerns that you have.

This should not be the first and only medicine you use for asthma or COPD. It will not stop an asthma attack that has already started. Your doctor may prescribe another medicine for you to use in case of an acute asthma attack or an acute COPD flare-up. If the other medicine does not work as well, tell your doctor right away.

Take all of your COPD medicines as your doctor ordered. If you use any type of corticosteroid medicine to control your breathing, keep using it as ordered by your doctor. Do not change your doses or stop using your medicines without first asking your doctor.

You or your child should not use this medicine if your asthma attack has already started or if you already have a severe asthma attack. Your doctor may prescribe another medicine (eg, a short-acting inhaler) for you to use in case of an acute asthma attack. Call your doctor immediately for instructions.

Do not use any other asthma medicine or medicine for breathing problems without talking to your doctor. This medicine should not be used with salmeterol (Serevent®), formoterol (Perforomist™), or arformoterol (Brovana®) inhalers.

Talk to your doctor or get medical care right away if:

Your or your child’s symptoms do not improve after using this medicine for 1 week or if they become worse.
Your short-acting inhaler does not seem to be working as well as usual and you need to use it more often (eg, you use 1 whole canister of your short-acting inhaler in 8 weeks time, or you need to use 4 or more inhalations of your short-acting inhaler for 2 or more days in a row).
You or your child have a significant decrease in your peak flow when measured as directed by your doctor.

Do not change your dose or stop using your medicine without first asking your doctor.

You may get infections more easily while using this medicine. Tell your doctor right away if you or your child have been exposed to someone with chickenpox or measles.

This medicine may cause fungus infection of the mouth or throat (thrush). Tell your doctor right away if you or your child have white patches in the mouth or throat, or pain when eating or swallowing.

Patients with COPD may be more likely to have pneumonia when taking this medicine. Check with your doctor if you start having increased sputum (spit) production, change in sputum color, fever, chills, increased cough, or an increase in breathing problems.

Using too much of this medicine or using it for a long time may increase your risk of having adrenal gland problems. Talk to your doctor if you or your child have more than one of these symptoms while you are using this medicine: darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.

This medicine may cause paradoxical bronchospasm, which may be life-threatening. Check with your doctor right away if you or your child are having a cough, difficulty with breathing, or wheezing.

If you or your child develop a skin rash, hives, or any allergic reaction to this medicine, check with your doctor right away.

This medicine may decrease bone mineral density when used for a long time. A low bone mineral density can cause weak bones or osteoporosis. If you have any questions about this, ask your doctor.

This medicine may cause children to grow more slowly than usual. Talk to your child’s doctor if you have any concerns.

This medicine may affect blood sugar and potassium levels. If you notice a change in the results of your blood or urine sugar or potassium tests or if you have any questions, check with your doctor.

Your doctor may want you to carry a medical identification (ID) card stating that you or your child are using this medicine and that you may need additional medicine during times of emergency, a severe asthma attack or other illness, or unusual stress.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Symbicort 200 Turbuhaler side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Body aches or pain
chills
cough
difficulty with breathing
ear congestion
fever
headache
loss of voice
muscle aches
pain or tenderness around the eyes and cheekbones
sneezing
sore throat
stuffy or runny nose
tightness of the chest
unusual tiredness or weakness

Less common

Bladder pain
bloody or cloudy urine
congestion
cough producing mucus
diarrhea
difficult, burning, or painful urination
dryness of the throat
fast, irregular, pounding, or racing heartbeat or pulse
frequent urge to urinate
general feeling of discomfort or illness
hoarseness
joint pain
loss of appetite
lower back or side pain
nausea
noisy breathing
shakiness in the legs, arms, hands, or feet
shivering
sore mouth or tongue
stomach pain
sweating
tender, swollen glands in the neck
trembling or shaking of the hands or feet
trouble with sleeping
trouble with swallowing
voice changes
vomiting
white patches in the mouth or on the tongue

Rare

Blurred vision
confusion
decreased urine
dizziness or lightheadedness when getting up suddenly from a lying or sitting position
dry mouth
enlarged pupils
fainting
flushed, dry skin
fruit-like breath odor
increased hunger
increased sensitivity of the eyes to light
increased sweating, possibly with fever or cold, clammy skin
increased thirst
increased urination
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
muscle cramps
nervousness
numbness or tingling in the hands, feet, or lips
pounding in the ears
seizures
severe chest pain
severe headache
slow, fast, pounding, or irregular heartbeat or pulse
stiff or sore neck
unexplained weight loss

Incidence not known

Blindness
decreased vision
eye pain
puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
tearing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Arm, back, or jaw pain
chest pain or discomfort
darkening of the skin
drowsiness
mental depression
rapid, deep breathing
restlessness
skin rash
stomach cramps

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Stomach discomfort

Less common

Belching
difficulty with moving
heartburn
indigestion
muscle spasms or stiffness
pain in the arms or legs
stomach upset
swollen joints

Rare

Bad, unusual, or unpleasant (after) taste
change in taste
deep or fast breathing with dizziness
fear
hives or welts, itching skin
irritability
large, flat, blue, or purplish patches in the skin
numbness in the feet, hands, and around the mouth
redness of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

Medical Disclaimer

The content of Holevn is solely for the purpose of providing information about Thuốc Symbicort 200 Turbuhaler (Inhalation) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/symbicort-200-turbuhaler.html

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