Thuốc Sodium fluoride

Thuốc Sodium fluoride
Thuốc Sodium fluoride

Holevn Health share articles about :Thuốc Sodium fluoride  , side effects – dosage , Thuốc Sodium fluoride what disease treatment.Other noted issues. Please refer to the details below.

SOE-dee-um FLOOR-ide

Medically reviewed by Last updated on Jul 11, 2019.

Commonly used brand name(s)

In the U.S.

  • APF Gel
  • Aquafresh
  • CaviRinse
  • Control Rx
  • Denta 5000 Plus
  • Dentagel
  • Dentall 1100 Plus
  • EtheDent
  • Fluorabon
  • Fluor-A-Day
  • Fluoridex Daily Defense
  • Fluoridex Daily Defense Enhanced Whitening

In Canada

  • Fluorosol
  • Koala Pals Fluoride Tooth Gel – Berrylicious Flavor
  • Pdf
  • Pedi-Dent

Available Dosage Forms:

  • Tablet, Chewable
  • Paste
  • Solution
  • Gel/Jelly
  • Suspension
  • Cream
  • Liquid

Therapeutic Class: Fluoride Supplement

Uses for sodium fluoride

Fluoride has been found to be helpful in reducing the number of cavities in the teeth. It is usually present naturally in drinking water. However, some areas of the country do not have a high enough level in the water to prevent cavities. To make up for this, extra fluoride may be added to the diet. Some children may require both dietary fluoride and topical fluoride treatments by the dentist. Use of a fluoride toothpaste or rinse may be helpful as well.

Taking extra oral fluoride does not replace good dental habits. These include eating a good diet, brushing and flossing the teeth often, and having regular dental checkups.

Fluoride may also be used for other conditions as determined by your doctor.

Sodium fluoride is available only with a prescription.

Importance of Diet

For good health, it is important that you eat a balanced and varied diet. Follow carefully any diet program your health care professional may recommend. For your specific dietary vitamin and/or mineral needs, ask your health care professional for a list of appropriate foods. If you think that you are not getting enough vitamins and/or minerals in your diet, you may choose to take a dietary supplement.

People get needed fluoride from fish, including the bones, tea, and drinking water that has fluoride added to it. Food that is cooked in water containing fluoride or in Teflon-coated pans also provides fluoride. However, foods cooked in aluminum pans provide less fluoride.

The daily amount of fluoride needed is defined in several different ways.

    For U.S.—

  • Recommended Dietary Allowances (RDAs) are the amount of vitamins and minerals needed to provide for adequate nutrition in most healthy persons. RDAs for a given nutrient may vary depending on a person’s age, sex, and physical condition (e.g., pregnancy).
  • Daily Values (DVs) are used on food and dietary supplement labels to indicate the percent of the recommended daily amount of each nutrient that a serving provides. DV replaces the previous designation of United States Recommended Daily Allowances (USRDAs).
    For Canada—

  • Recommended Nutrient Intakes (RNIs) are used to determine the amounts of vitamins, minerals, and protein needed to provide adequate nutrition and lessen the risk of chronic disease.

There is no RDA or RNI for fluoride. Daily recommended intakes for fluoride are generally defined as follows:

    Infants and children—

  • Birth to 3 years of age: 0.1 to 1.5 milligrams (mg).
  • 4 to 6 years of age: 1 to 2.5 mg.
  • 7 to 10 years of age: 1.5 to 2.5 mg.
    Adolescents and adults—

  • 1.5 to 4 mg.


  • The total amount of fluoride you get every day includes what you get from the foods and beverages that you eat and what you may take as a supplement.
  • This total amount should not be greater than the above recommendations, unless ordered by your health care professional. Taking too much fluoride can cause serious problems to the teeth and bones.

Before using sodium fluoride

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For sodium fluoride, the following should be considered:


Tell your doctor if you have ever had any unusual or allergic reaction to sodium fluoride or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.


Problems in children have not been reported with intake of normal daily recommended amounts. Doses of sodium fluoride that are too large or are taken for a long time may cause bone problems and teeth discoloration in children.


Problems in older adults have not been reported with intake of normal daily recommended amounts. Older people are more likely to have joint pain, kidney problems, or stomach ulcers which may be made worse by taking large doses of sodium fluoride. You should check with your health care professional.


Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using sodium fluoride with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use sodium fluoride, or give you special instructions about the use of food, alcohol, or tobacco.

  • Dairy Food

Other medical problems

The presence of other medical problems may affect the use of sodium fluoride. Make sure you tell your doctor if you have any other medical problems, especially:

  • Brown, white, or black discoloration of teeth or
  • Joint pain or
  • Kidney problems (severe) or
  • Stomach ulcer—Sodium fluoride may make these conditions worse.

Proper use of sodium fluoride

Take sodium fluoride only as directed by your health care professional. Do not take more of it and do not take it more often than ordered. Taking too much fluoride over a period of time may cause unwanted effects.

For individuals taking the chewable tablet form of sodium fluoride:

  • Tablets should be chewed or crushed before they are swallowed.
  • Sodium fluoride works best if it is taken at bedtime, after the teeth have been thoroughly brushed. Do not eat or drink for at least 15 minutes after taking sodium fluoride.

For individuals taking the oral liquid form of sodium fluoride:

  • Sodium fluoride is to be taken by mouth even though it comes in a dropper bottle. The amount to be taken is to be measured with the specially marked dropper.
  • Always store sodium fluoride in the original plastic container. Fluoride will affect glass and should not be stored in glass containers.
  • Sodium fluoride may be dropped directly into the mouth or mixed with cereal, fruit juice, or other food. However, if sodium fluoride is mixed with foods or beverages that contain calcium, the amount of sodium fluoride that is absorbed may be reduced.


The dose of sodium fluoride will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of sodium fluoride. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (lozenges, solution, tablets, or chewable tablets):
    • To prevent cavities in the teeth (not enough fluoride in the water):
      • Children—Dose is based on the amount of fluoride in drinking water in your area. Dose is also based on the child’s age and must be determined by your health care professional.

Missed dose

If you miss a dose of sodium fluoride, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Precautions while using sodium fluoride

The level of fluoride present in the water is different in different parts of the U.S. If you move to another area, check with a health care professional in the new area as soon as possible to see if sodium fluoride is still needed or if the dose needs to be changed. Also, check with your health care professional if you change infant feeding habits (e.g., breast-feeding to infant formula), drinking water (e.g., city water to nonfluoridated bottled water), or filtration (e.g., tap water to filtered tap water).

Do not take calcium supplements or aluminum hydroxide–containing products and sodium fluoride at the same time. It is best to space doses of these two products 2 hours apart, to get the full benefit from each medicine.

Inform your health care professional as soon as possible if you notice white, brown, or black spots on the teeth. These are signs of too much fluoride in children when it is given during periods of tooth development.

Sodium fluoride side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor as soon as possible if any of the following side effects occur:

Sodium fluoride in drinking water or taken as a supplement does not usually cause any side effects. However, taking an overdose of fluoride may cause serious problems.

  • Sores in the mouth and on the lips (rare)

Stop taking sodium fluoride and get emergency help immediately if any of the following effects occur:

  • Black, tarry stools
  • bloody vomit
  • diarrhea
  • drowsiness
  • faintness
  • increased watering of the mouth
  • nausea or vomiting
  • shallow breathing
  • stomach cramps or pain
  • tremors
  • unusual excitement
  • watery eyes
  • weakness

Check with your doctor as soon as possible if any of the following side effects occur:

  • Pain and aching of bones
  • stiffness
  • white, brown, or black discoloration of the teeth—occurs only during periods of tooth development in children

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Sodium fluoride  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

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