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Generic Name: risankizumab (RIS an KIZ ue mab)
Medically reviewed by Holevn.org on Jul 15, 2019 – Written by Cerner Multum
What is risankizumab?
Risankizumab is used to treat moderate to severe plaque psoriasis in adults.
Risankizumab may also be used for purposes not listed in this medication guide.
Risankizumab affects your immune system. You may get infections more easily. Call your doctor if you have symptoms such as fever, chills, cough, trouble breathing, diarrhea, burning when you urinate, weight loss, or skin sores on your body (different from psoriasis).
Before taking this medicine
Before you start treatment with risankizumab, your doctor may perform tests to make sure you do not have tuberculosis or other infections.
Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.
Tell your doctor if you currently have signs of infection such as fever, chills, muscle pain, cough, trouble breathing, skin sores, stomach pain, diarrhea, weight loss, or painful urination.
Make sure you are current on all vaccines before you begin treatment with risankizumab.
Tell your doctor if you are pregnant or breastfeeding.
Risankizumab is not approved for use by anyone younger than 18 years old.
How should I use risankizumab?
Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.
Risankizumab is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.
Read and carefully follow any Instructions for Use provided with your medicine. You may need to use 2 injections to get your total dose. Ask your doctor or pharmacist if you don’t understand all instructions.
Risankizumab should be clear or light-yellow. Do not use if the medicine looks cloudy, has changed colors, or has flakes or large particles in it. Call your pharmacist for new medicine.
Your care provider will show you where on your body to inject risankizumab. Do not inject into skin with active psoriasis, or skin that is red, bruised, or tender. Do not inject within 2 inches of your navel (belly button).
Risankizumab affects your immune system. You may get infections more easily. Your doctor will need to examine you on a regular basis.
Store risankizumab in the original container in a refrigerator. Protect from light and do not shake or freeze. Take the medicine out of the refrigerator and allow it to reach room temperature for 15 to 30 minutes before injecting your dose. Do not heat the medicine in a microwave or with hot water.
Each prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.
Use a needle and syringe only once and then place them in a puncture-proof “sharps” container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.
What happens if I miss a dose?
Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call 115.
What should I avoid while using risankizumab?
Do not receive a “live” vaccine while using risankizumab. The vaccine may not work as well and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.
Risankizumab side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
You may get infections more easily. Call your doctor right away if you have signs of infection such as:
fever, chills, sweating, body aches;
shortness of breath, cough, bloody mucus;
mouth sores, red or swollen gums;
stomach pain, diarrhea;
increased urination, burning when you urinate;
pale skin, easy bruising, unusual bleeding;
a fungal skin infection–skin sores different from psoriasis, rash or redness, blisters, itching, burning, cracking or peeling, changes in skin color; or
signs of tuberculosis: fever, cough, night sweats, loss of appetite, weight loss, and feeling very tired.
If you develop an infection, you may need to postpone your next injection until the infection clears up.
Common side effects may include:
cold symptoms such as stuffy nose, sneezing, sore throat;
fungal skin infections; or
pain, redness, itching, bruising, swelling, warmth, bleeding, burning, or other skin irritation where the medicine was injected.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Risankizumab dosing information
Usual Adult Dose for Plaque Psoriasis:
150 mg (two 75 mg injections) subcutaneously at Week 0, Week 4, and every 12 weeks thereafter
-Evaluate patients for tuberculosis (TB) infection prior to initiating this drug.
Use: For the treatment of moderate to severe plaque psoriasis in adults who are candidates for systemic therapy or phototherapy
What other drugs will affect risankizumab?
Other drugs may affect risankizumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 1.02.
The content of Holevn is solely for the purpose of providing information about Thuốc Risankizumab and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/mtm/risankizumab.html