Thuốc Robinul (Oral)

29/03/2020

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Holevn Health share articles about :Thuốc Robinul (Oral) , side effects – dosage , Thuốc Robinul (Oral) what disease treatment.Other noted issues. Please refer to the details below.

Generic Name: glycopyrrolate (Oral route)

glye-koe-PIR-oh-late

Medically reviewed by Holevn.org. Last updated on Aug 18, 2019.

The Robinul brand name has been discontinued in the U.S. If generic versions of this product have been approved by the FDA, there may be generic equivalents available.

Commonly used brand name(s)

In the U.S.

Cuvposa
Glycate
Robinul
Robinul Forte

Available Dosage Forms:

Tablet
Solution

Therapeutic Class: Gastrointestinal Agent

Pharmacologic Class: Antimuscarinic

Uses for Robinul

Glycopyrrolate is used to treat peptic ulcers in adults. It is also used to treat chronic, severe drooling caused by certain neurologic disorders (e.g., cerebral palsy) in children 3 to 16 years of age. This medicine is an anticholinergic.

Glycopyrrolate may also be used for other conditions as determined by your doctor.

This medicine is available only with your doctor’s prescription.

Before using Robinul

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of glycopyrrolate in children 3 to 16 years of age. However, safety and efficacy have not been established in children younger than 3 years of age.

Geriatric

No information is available on whether the risk of glycopyrrolate-induced adverse effects are increased in the elderly; however, it should be used with caution because elderly patients are more likely to have age related liver disease, kidney disease, heart disease, or prostate problems. This may require a dosage adjustment or careful monitoring in elderly patients receiving glycopyrrolate.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Potassium

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Amifampridine
Amitriptyline
Amoxapine
Atropine
Belladonna
Benztropine
Biperiden
Brompheniramine
Bupropion
Carbinoxamine
Carisoprodol
Chlorpheniramine
Chlorpromazine
Clemastine
Clidinium
Clomipramine
Clozapine
Cyclobenzaprine
Cyclopentolate
Cyproheptadine
Darifenacin
Desipramine
Dicyclomine
Dimenhydrinate
Diphenhydramine
Donepezil
Doxepin
Flavoxate
Fluphenazine
Glycopyrronium Tosylate
Homatropine
Hydroxyzine
Hyoscyamine
Imipramine
Ipratropium
Loxapine
Meclizine
Mepenzolate
Methacholine
Nortriptyline
Olanzapine
Orphenadrine
Oxitropium Bromide
Oxybutynin
Paroxetine
Perphenazine
Pimozide
Pipenzolate Bromide
Pirenzepine
Prochlorperazine
Procyclidine
Promethazine
Propantheline
Propiverine
Protriptyline
Scopolamine
Secretin Human
Solifenacin
Stramonium
Terodiline
Thioridazine
Thiothixene
Tiotropium
Tizanidine
Tolterodine
Trifluoperazine
Trihexyphenidyl
Trimipramine
Tropicamide
Trospium
Umeclidinium

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper use of Robinul

This section provides information on the proper use of a number of products that contain glycopyrrolate. It may not be specific to Robinul. Please read with care.

Your doctor will tell you how much of this medicine to use and how often. The dose may need to be changed several times in order to find out what works best for you or your child. Do not use more medicine or use it more often than your doctor tells you to.

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.

You should take this medicine at least one hour before or two hours after meals.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (solution):
- For severe drooling:
  - Children 3 to 16 years of age—Dose is based on body weight and must be determined by your child’s doctor. The dose is 0.02 milligram (mg) per kilogram (kg) of body weight three times a day. Your child’s doctor may increase your child’s dose as needed. However, the dose is usually not more than 1.5 to 3 mg per dose.
  - Children younger than 3 years of age—Use and dose must be determined by your child’s doctor.
For oral dosage form (tablet):
- For peptic ulcers:
  - Adults and children 12 years of age and older—The initial dose is 1 mg three times daily. Your doctor will adjust the dose as needed. However, the dose is usually not more than 8 mg per day.
  - Children younger than 12 years of age—Use is not recommended.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using Robinul

It is very important that your doctor or your child’s doctor check your progress at regular visits. This will allow your doctor to make sure that this medicine is working properly and to check for unwanted effects.

You should not take potassium chloride tablets or other potassium supplements (in tablet or capsule forms) while is using this medicine. Using these medicines together may cause delayed movement of the potassium supplement through the esophagus and stomach.

This medicine may cause constipation or diarrhea. Constipation or diarrhea can be an early symptom of a serious bowel problem. Stop using this medicine and check with your doctor if you or your child has constipation, diarrhea, abdominal or stomach distention (swelling), pain, nausea, or vomiting.

Stop using this medicine and check with your doctor right away if your child is unable to urinate, has dry diapers or undergarments, or has the following symptoms while using this medicine: crying, irritability, decrease in the frequency of urine, or difficult or painful urination.

If you or your child develops a skin rash, hives, or any allergic reaction to this medicine, stop taking the medicine and check with your doctor as soon as possible.

This medicine may make you or your child sweat less, causing your body temperature to increase. Use extra care to avoid becoming overheated during exercise or hot weather while you are taking this medicine, since overheating may result in heat stroke.

This medicine may make you or your child drowsy or cause blurred vision. Avoid driving, using machines, or doing anything else that could be dangerous if you are not alert.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Robinul side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Body aches or pain
chills
constipation
cough
decrease in the frequency of urination
decrease in urine volume
difficulty in passing urine (dribbling)
difficulty with breathing
ear congestion
feeling of warmth
fever
headache
loss of voice
nasal congestion
painful urination
redness of the face, neck, arms, and occasionally, upper chest
runny nose
sneezing
sore throat
unusual tiredness or weakness

Less common

Abdominal or stomach discomfort or pain
abdominal or stomach distension
chest pain
confusion
convulsions
dizziness
dry heaves
dry mouth
fainting
increase in heart rate
lightheadedness
pain or tenderness around the eyes and cheekbones
rapid breathing
shortness of breath or troubled breathing
stuffy nose
sunken eyes
thirst
tightness in the chest
vomiting
wheezing
wrinkled skin

Get emergency help immediately if any of the following symptoms of overdose occur:

low blood pressure
muscle weakness
trouble breathing

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common

Altered mood
anxiety
attack, assault, or force
bloated
change in taste
chapped lips
crying
dry skin
dry tongue
excess air or gas in the stomach or intestines
full feeling
hyperventilation
irregular heartbeats
irritability
loss of taste
moaning
nervousness
pain
paleness of the skin
passing gas
rash
restlessness
shaking
trouble with sleeping
uncontrolled eye movements

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

Medical Disclaimer

The content of Holevn is solely for the purpose of providing information about Thuốc Robinul (Oral) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/robinul.html

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