Thuốc Omadacycline (Oral)

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Thuốc Omadacycline (Oral)
Thuốc Omadacycline (Oral)

Holevn Health share articles about :Thuốc Omadacycline (Oral)  , side effects – dosage , Thuốc Omadacycline (Oral) what disease treatment.Other noted issues. Please refer to the details below.

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Medically reviewed by Holevn.org. Last updated on Dec 17, 2019.

Commonly used brand name(s)

In the U.S.

  • Nuzyra

Available Dosage Forms:

  • Tablet

Therapeutic Class: Antibacterial

Chemical Class: Tetracycline (class)

Uses for omadacycline

Omadacycline is used to treat community acquired bacterial pneumonia (CABP) and acute bacterial skin and skin structure infections (ABSSSI).

Omadacycline belongs to the class of medicines known as tetracycline antibiotics. It works by killing bacteria or preventing their growth. However, omadacycline will not work for colds, flu, or other virus infections.

Omadacycline is available only with your doctor’s prescription.

Before using omadacycline

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For omadacycline, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to omadacycline or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Omadacycline may cause permanent discoloration of the teeth and slow down bone growth. Omadacycline should not be given to children younger than 8 years of age, unless directed by the child’s doctor.

Geriatric

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of omadacycline in the elderly.

Breastfeeding

There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking omadacycline, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using omadacycline with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Acenocoumarol
  • Apixaban
  • Ardeparin
  • Argatroban
  • Betrixaban
  • Bivalirudin
  • Certoparin
  • Dabigatran Etexilate
  • Dalteparin
  • Danaparoid
  • Desirudin
  • Edoxaban
  • Enoxaparin
  • Fondaparinux
  • Heparin
  • Lepirudin
  • Parnaparin
  • Phenindione
  • Phenprocoumon
  • Protein C
  • Reviparin
  • Rivaroxaban
  • Tinzaparin
  • Warfarin

Using omadacycline with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

  • Aluminum Carbonate, Basic
  • Aluminum Hydroxide
  • Aluminum Phosphate
  • Bismuth Subsalicylate
  • Calcium
  • Dihydroxyaluminum Aminoacetate
  • Dihydroxyaluminum Sodium Carbonate
  • Iron
  • Magaldrate
  • Magnesium Carbonate
  • Magnesium Hydroxide
  • Magnesium Oxide
  • Magnesium Trisilicate

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Other medical problems

The presence of other medical problems may affect the use of omadacycline. Make sure you tell your doctor if you have any other medical problems, especially:

  • Diarrhea or
  • Eye or vision problems—Use with caution. May make these conditions worse.

Proper use of omadacycline

Take omadacycline only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

Do not eat or drink (except water) 4 hours before and 2 hours after using omadacycline.

Do not eat dairy products or take antacids or multivitamins (containing aluminum, calcium, magnesium, bismuth subsalicylate, or iron) for 4 hours after using omadacycline.

Keep using omadacycline for the full time of treatment, even if you begin to feel better after a few days. If you stop taking omadacycline too soon, your infection may not clear up.

Dosing

The dose of omadacycline will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of omadacycline. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (tablets):
    • For acute bacterial skin and skin structure infections:
      • Adults and children 8 years of age and older—450 milligrams (mg) once a day on Day 1 and 2, then 300 mg once a day for 7 to 14 days.
      • Children younger than 8 years of age—Use is not recommended.
    • For community-acquired bacterial pneumonia:
      • Adults and children 8 years of age and older—300 milligrams (mg) once a day for 7 to 14 days.
      • Children younger than 8 years of age—Use is not recommended.

Missed dose

If you miss a dose of omadacycline, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using omadacycline

It is very important that your doctor check your progress at regular visits to make sure that omadacycline is working properly. Blood and urine tests may be needed to check for unwanted effects.

If your symptoms do not improve within a few days, or if they become worse, check with your doctor.

Using omadacycline while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using omadacycline, tell your doctor right away.

Omadacycline may cause serious allergic reactions, which can be life-threatening and require immediate medical attention. Tell your doctor right away if you have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using omadacycline.

Omadacycline may cause diarrhea, and in some cases it can be severe. It may occur 2 months or more after you stop taking omadacycline. Do not take any medicine to treat diarrhea without first checking with your doctor. Diarrhea medicines may make the diarrhea worse or make it last longer. If you have any questions about this or if mild diarrhea continues or gets worse, check with your doctor.

Omadacycline may cause intracranial hypertension (increased pressure in the head). Tell your doctor right away if you have a headache, blurred vision, or other change in vision.

Omadacycline may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for short periods of time, may cause skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking omadacycline:

  • Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
  • Wear protective clothing, including a hat. Also, wear sunglasses.
  • Apply a sunblock product that has a sun protection factor (SPF) number of at least 15. Some patients may require a product with a higher SPF number, especially if they have a fair complexion. If you have any questions about this, check with your doctor.
  • Apply a sunblock lipstick that has an SPF of at least 15 to protect your lips.
  • Do not use a sun lamp or tanning bed or booth.

If you have a severe reaction from the sun, check with your doctor right away.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Omadacycline side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Less common

  • Blurred vision
  • dizziness
  • fainting
  • fast, pounding, or irregular heartbeat or pulse
  • fever
  • headache
  • hives, itching, skin rash
  • hoarseness
  • irritation
  • itching of the vagina or genitals
  • joint pain, stiffness, or swelling
  • nervousness
  • pale skin
  • pounding in the ears
  • redness of the skin
  • sore mouth or tongue
  • stomach pain
  • swelling of the eyelids, face, lips, hands, or feet
  • thick, white vaginal discharge with mild or no odor
  • tightness in the chest
  • troubled breathing or swallowing
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness
  • white patches in the mouth or on the tongue

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Nausea
  • vomiting

Less common

  • Belching
  • change or loss in taste
  • constipation
  • diarrhea
  • feeling of constant movement of self or surroundings
  • heartburn
  • increased sweating
  • indigestion
  • mouth or throat pain
  • sensation of spinning
  • stomach discomfort or upset
  • trouble sleeping
  • unusual drowsiness, dullness, or feeling of sluggishness

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

Related questions

The content of Holevn is solely for the purpose of providing information about Thuốc Omadacycline (Oral)  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/omadacycline.html

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