Holevn Health share articles about :Thuốc Myfortic , side effects – dosage , Thuốc Myfortic what disease treatment.Other noted issues. Please refer to the details below.
Generic Name: mycophenolic acid (MYE koe phe NOLE ik AS id)
Brand Names:Myfortic
Medically reviewed by Jane Grigg, DipPharm Last updated on Jul 1, 2019.
What is Myfortic?
Myfortic (mycophenolic acid) is an immunosuppressant that weakens your body’s immune system. Your body may “reject” an organ transplant when the immune system treats the new organ as an invader and attacks it. An immunosuppressant helps to prevent this rejection.
Myfortic is used to prevent your body from rejecting a kidney transplant.
Myfortic is usually given with cyclosporine and a steroid medicine.
Important Information
Myfortic may cause your body to overproduce white blood cells. This can lead to cancer, severe brain infection causing disability or death, or a viral infection causing kidney transplant failure.
Call your doctor right away if you have: fever, swollen glands, flu symptoms, vomiting, diarrhea, painful urination, easy bruising or bleeding, mouth sores, a new skin lesion, skin sores that are red or oozing, any change in your mental state, weakness on one side of your body, or tenderness near your transplanted kidney.
Myfortic can cause a miscarriage or birth defects when used during the first 3 months of pregnancy. If you are able to get pregnant, you must use birth control during and shortly after treatment with Myfortic.
Myfortic is sometimes given to pregnant women. Although this medicine can affect pregnancy or fertility, it is sometimes given to women who are unable to use other needed transplant medications.
Before taking this medicine
You should not use Myfortic if you are allergic to mycophenolic acid or mycophenolate mofetil (CellCept).
Myfortic affects your immune system, and may cause certain white blood cells to grow out of control. This can lead to cancer, severe brain infection causing disability or death, or a viral infection causing kidney transplant failure. Talk with your doctor about the risks of using this medicine.
Tell your doctor if you have ever had:
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a stomach ulcer or problems with digestion;
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hepatitis B or C;
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a viral, bacterial, or fungal infection; or
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a rare inherited enzyme deficiency such as Lesch-Nyhan syndrome or Kelley-Seegmiller syndrome.
Mycophenolic acid can cause a miscarriage or birth defects, especially during the first 3 months of pregnancy. You will need to have a negative pregnancy test before and during treatment with this medicine. If you are able to get pregnant, you must use specific forms of birth control to prevent pregnancy while using Myfortic, and for at least 6 weeks after your last dose.
You are considered able to get pregnant (even if you are not sexually active) from the age of puberty until you have been in menopause for at least 12 months in a row.
Myfortic can make hormonal birth control (pills, injections, implants, skin patches, or vaginal rings) less effective. You must also use a back-up barrier method (such as a cervical sponge, a male or female condom, or a diaphragm or cervical cap used together with spermicide).
You do not need to use additional birth control if you use an intrauterine device (IUD), if you have had a tubal ligation, or if your sexual partner has had a vasectomy.
This medicine comes with patient instructions about the most effective non-hormonal forms of birth control to use. Follow these directions carefully. Ask your doctor if you have any questions.
If a pregnancy occurs during treatment, do not stop taking Myfortic. Call your doctor for instructions. Also call the Mycophenolate Pregnancy Registry (1-800-617-8191).
Myfortic is sometimes given to pregnant women. Your doctor will decide whether you should use this medicine if you are are unable to use other needed transplant medications.
You should not breast-feed while using Myfortic.
How should I take Myfortic?
Take Myfortic exactly as prescribed by your docto Follow all directions on your prescription label and read all medication guides or instruction sheets.
You must remain under the care of a doctor while you are using Myfortic.
Take Myfortic on an empty stomach, at least 1 hour before or 2 hours after a meal.
Swallow the tablet whole and do not crush, chew, or break it.
Mycophenolic acid (Myfortic) and mycophenolate mofetil (CellCept – a similar medicine also used to help the body from harming an organ after an organ transplant) are not absorbed equally in the body. Your dose needs may change if you switch to a different brand, strength, or form of this medicine. Avoid medication errors by using only the form and strength your doctor prescribes.
You will need frequent medical tests.
If you have ever had hepatitis B or C, mycophenolic acid can cause this virus to become active or get worse. You may need frequent liver function tests while using this medicine and for several months after you stop.
Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.
Myfortic dosing information
Usual Adult Dose for Organ Transplant — Rejection Prophylaxis:
720 mg orally 2 times daily
Comments:
-This drug should be used in combination with cyclosporine and corticosteroids.
-Take on an empty stomach 1 hour before or 2 hours after food.
-Swallow tablets whole; do not crush, chew, or divide.
Use: For prophylaxis of organ rejection in kidney transplant
Usual Pediatric Dose for Organ Transplant — Rejection Prophylaxis:
5 years and older:
-In conversion (at least 6 months posttransplant): 400 mg/m2 orally 2 times a day (up to a maximum dose of 720 mg 2 times a day)
Note: Pediatric patients with a BSA of 1.19 to 1.58 m2 may be dosed either with three of the 180 mg tablets, or one 180 mg tablet plus one 360 mg tablet 2 times a day. Patients with a BSA greater than 1.58 m2 may be dosed either with four of the 180 mg tablets, or two of the 360 mg tablets twice daily. Pediatric doses for patients with BSA less than 1.19 m2 cannot be accurately administered using currently available formulations of this drug.
Comments:
-This drug should be used in combination with cyclosporine and corticosteroids.
-Take on an empty stomach 1 hour before or 2 hours after food.
-Swallow tablets whole; do not crush, chew, or divide.
Use: For the prophylaxis of organ rejection in pediatric patients 5 years of age and older who are at least 6 months post kidney transplant
What happens if I miss a dose?
Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call 115.
What should I avoid while taking Myfortic?
Avoid taking an antacid together with Myfortic.
Avoid being near people who are sick or have infections. Tell your doctor at once if you develop signs of infection.
Do not receive a “live” vaccine while using Myfortic. The vaccine may not work as well during this time, and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), and zoster (shingles).
Myfortic can make you sunburn more easily. Avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Myfortic side effects
Get emergency medical help if you have signs of an allergic reaction to Myfortic: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Myfortic can affect your immune system, and may cause certain white blood cells to grow out of control. Call your doctor right away if you have:
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fever, swollen glands, painful mouth sores, cold or flu symptoms, headache, ear pain;
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stomach pain, vomiting, diarrhea, weight loss;
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weakness on one side of your body, loss of muscle control;
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confusion, thinking problems, loss of interest in things that normally interest you;
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pain or burning when you urinate;
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tenderness around the transplanted kidney;
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swelling, warmth, redness, or oozing around a skin wound; or
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a new skin lesion, or a mole that has changed in size or color.
Also call your doctor at once if you have:
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bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds; or
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low blood cell counts – fever, chills, tiredness, flu-like symptoms, mouth sores, skin sores, easy bruising, unusual bleeding, pale skin, cold hands and feet, feeling light-headed or short of breath.
Side effects may be more likely in older adults.
Common Myfortic side effects may include:
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indigestion, nausea, vomiting;
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diarrhea, constipation;
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low blood cell counts;
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sleep problems (insomnia); or
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pain after surgery.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Myfortic?
Tell your doctor about all your other medicines, especially:
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azathioprine;
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cholestyramine; or
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antiviral medicine – acyclovir, ganciclovir.
This list is not complete. Other drugs may interact with mycophenolic acid, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible drug interactions are listed here.
Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Myfortic only for the indication prescribed.
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Medical Disclaimer
The content of Holevn is solely for the purpose of providing information about Thuốc Myfortic and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/myfortic.html