Thuốc Levorphanol

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Thuốc Levorphanol
Thuốc Levorphanol

Levorphanol side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing, breathing that stops during sleep;

  • a slow heart rate or weak pulse;

  • a light-headed feeling, like you might pass out;

  • mood changes, unusual thoughts or behavior;

  • severe stomach pain, severe constipation; or

  • low cortisol levels– nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, confusion, fever, sweating, fast heart rate, chest pain, feeling short of breath, muscle stiffness, trouble walking, or feeling faint.

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.

Common side effects may include:

  • nausea, vomiting, stomach pain;

  • constipation;

  • dizziness, drowsiness;

  • tiredness; or

  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Levorphanol dosing information

Usual Adult Dose for Pain:

As First Opioid Analgesic:
Initial dose: 1 to 2 mg orally every 6 to 8 hours as needed for pain
-May increase dose up to 3 mg orally every 6 to 8 hours as needed; if around the clock dosing is used, allow 72 hours for patient to reach a new steady-state before dose adjustment
Maximum doses: Higher doses may be appropriate in opioid tolerant patients

CONVERSION from other Opioids:
-Due to inter-patient variability, a conservative approach is advised
-Levorphanol is 4 to 8 times as potent as morphine and has a longer half-life
-May consider initiating levorphanol at 1/15 to 1/12 the total daily dose of oral morphine and adjust to clinical response
-Allow 72 hours for patient to reach a new steady-state before dose adjustment

Comments:
-Doses should be adjusted according to the severity of the pain, age, weight, and physical status, underlying disease, and use of concomitant medications.
-Monitor closely for respiratory depression especially on initiation and with each dose increase.
-Because of the risks of addiction, abuse, and misuse, even at recommended doses, this drug should be reserved for use in patients for whom alternative treatment options have not or are not expected to be tolerated or have not or are not expected to provide adequate analgesia.

Use: For the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

What other drugs will affect levorphanol?

Opioid medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:

  • cold or allergy medicines, bronchodilator asthma/COPD medication, or a diuretic (“water pill”);

  • medicines for motion sickness, irritable bowel syndrome, or overactive bladder;

  • other narcotic medications–opioid pain medicine or prescription cough medicine;

  • a sedative like Valium–diazepam, alprazolam, lorazepam, Xanax, Klonopin, Ativan, and others;

  • drugs that make you sleepy or slow your breathing–a sleeping pill, muscle relaxer, medicine to treat mood disorders or mental illness; or

  • drugs that affect serotonin levels in your body–a stimulant, or medicine for depression, Parkinson’s disease, migraine headaches, serious infections, or nausea and vomiting.

This list is not complete. Other drugs may affect levorphanol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

The content of Holevn is solely for the purpose of providing information about Thuốc Levorphanol  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/mtm/levorphanol.html

Never crush or break a levorphanol pill to inhale the powder or mix it into a liquid to inject the drug into your vein. Doing so could result in death.

Store at room temperature away from moisture and heat. Keep track of your medicine. You should be aware if anyone is using it improperly or without a prescription.

Do not keep leftover opioid medication. Just one dose can cause death in someone using this medicine accidentally or improperly. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, flush the unused medicine down the toilet.

What happens if I miss a dose?

Since levorphanol is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call 115. A levorphanol overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include slow breathing and heart rate, severe drowsiness, muscle weakness, cold and clammy skin, pinpoint pupils, or coma.

What should I avoid while taking levorphanol?

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how levorphanol will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Levorphanol side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Opioid medicine can slow or stop your breathing, and death may occur. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.

Call your doctor at once if you have:

  • noisy breathing, sighing, shallow breathing, breathing that stops during sleep;

  • a slow heart rate or weak pulse;

  • a light-headed feeling, like you might pass out;

  • mood changes, unusual thoughts or behavior;

  • severe stomach pain, severe constipation; or

  • low cortisol levels– nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.

Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, confusion, fever, sweating, fast heart rate, chest pain, feeling short of breath, muscle stiffness, trouble walking, or feeling faint.

Serious side effects may be more likely in older adults and those who are overweight, malnourished, or debilitated.

Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.

Common side effects may include:

  • nausea, vomiting, stomach pain;

  • constipation;

  • dizziness, drowsiness;

  • tiredness; or

  • headache.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Levorphanol dosing information

Usual Adult Dose for Pain:

As First Opioid Analgesic:
Initial dose: 1 to 2 mg orally every 6 to 8 hours as needed for pain
-May increase dose up to 3 mg orally every 6 to 8 hours as needed; if around the clock dosing is used, allow 72 hours for patient to reach a new steady-state before dose adjustment
Maximum doses: Higher doses may be appropriate in opioid tolerant patients

CONVERSION from other Opioids:
-Due to inter-patient variability, a conservative approach is advised
-Levorphanol is 4 to 8 times as potent as morphine and has a longer half-life
-May consider initiating levorphanol at 1/15 to 1/12 the total daily dose of oral morphine and adjust to clinical response
-Allow 72 hours for patient to reach a new steady-state before dose adjustment

Comments:
-Doses should be adjusted according to the severity of the pain, age, weight, and physical status, underlying disease, and use of concomitant medications.
-Monitor closely for respiratory depression especially on initiation and with each dose increase.
-Because of the risks of addiction, abuse, and misuse, even at recommended doses, this drug should be reserved for use in patients for whom alternative treatment options have not or are not expected to be tolerated or have not or are not expected to provide adequate analgesia.

Use: For the management of pain severe enough to require an opioid analgesic and for which alternative treatments are inadequate.

What other drugs will affect levorphanol?

Opioid medication can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:

  • cold or allergy medicines, bronchodilator asthma/COPD medication, or a diuretic (“water pill”);

  • medicines for motion sickness, irritable bowel syndrome, or overactive bladder;

  • other narcotic medications–opioid pain medicine or prescription cough medicine;

  • a sedative like Valium–diazepam, alprazolam, lorazepam, Xanax, Klonopin, Ativan, and others;

  • drugs that make you sleepy or slow your breathing–a sleeping pill, muscle relaxer, medicine to treat mood disorders or mental illness; or

  • drugs that affect serotonin levels in your body–a stimulant, or medicine for depression, Parkinson’s disease, migraine headaches, serious infections, or nausea and vomiting.

This list is not complete. Other drugs may affect levorphanol, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

The content of Holevn is solely for the purpose of providing information about Thuốc Levorphanol  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/mtm/levorphanol.html

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