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Generic Name: levonorgestrel intrauterine system (LEE voe nor JES trel IN tra UE ter ine SIS tem)
Brand Name:Kyleena, Liletta, Mirena, Skyla
Medically reviewed by Holevn.org on Jul 18, 2019 – Written by Cerner Multum
What is Kyleena?
Levonorgestrel is a female hormone that can cause changes in your cervix, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus. Kyleena is a plastic device that is placed in the uterus where it slowly releases the hormone to prevent pregnancy for up to 5 years.
Kyleena is used to prevent pregnancy for up to 5 years. You may use this device whether you have children or not. Mirena is also used to treat heavy menstrual bleeding in women who choose to use an intrauterine form of birth control.
Levonorgestrel is a progestin hormone and does not contain estrogen. The intrauterine device (IUD) releases levonorgestrel in the uterus, but only small amounts of the hormone reach the bloodstream. Kyleena should not be used as emergency birth control.
Kyleena may also be used for purposes not listed in this medication guide.
You should not use this intrauterine device if you have abnormal vaginal bleeding, a pelvic infection, certain other problems with your uterus or cervix, or if you have breast or uterine cancer, liver disease or liver tumor, or a weak immune system.
Do not use during pregnancy. Call your doctor if you miss a period or think you might be pregnant.
Before taking this medicine
An intrauterine device can increase your risk of developing a serious pelvic infection, which may threaten your life or your future ability to have children. Ask your doctor about your personal risk.
Do not use this IUD during pregnancy. This device can cause severe infection, miscarriage, premature birth, or death of the mother if left in place during pregnancy. Tell your doctor right away if you become pregnant. If you choose to continue a pregnancy that occurs while using a Kyleena, watch for signs of infection such as fever, chills, flu symptoms, cramps, vaginal bleeding or discharge.
You should not use this device if you are allergic to levonorgestrel, silicone, silica, silver, barium, iron oxide, or polyethylene, or if you have:
abnormal vaginal bleeding that has not been checked by a doctor;
an untreated or uncontrolled pelvic infection (vaginal, cervical uterine, or bladder);
endometriosis or a serious pelvic infection following a pregnancy or abortion within the past 3 months;
a history of pelvic inflammatory disease (PID), unless you have had a normal pregnancy after the infection was treated and cleared;
uterine fibroid tumors or other conditions that affect the shape of the uterus;
past or present breast cancer, known or suspected cervical or uterine cancer;
liver disease or liver tumor (benign or malignant);
a recent abnormal Pap smear that has not yet been diagnosed or treated;
a disease or condition that weakens your immune system, such as AIDS, leukemia, or IV drug abuse; or
if you have another intrauterine device (IUD) in place.
To make sure levonorgestrel is safe for you, tell your doctor if you have ever had:
high blood pressure, heart disease or a heart valve disorder;
a heart attack or stroke;
a bleeding or blood-clotting disorder;
migraine headaches; or
a vaginal infection, pelvic infection, or sexually transmitted disease.
You should not use this IUD if you are breast-feeding a baby younger than 6 weeks old. This IUD may be more likely to form a hole or get embedded in the wall of your uterus if you have the device inserted while you are breast-feeding.
How is Kyleena used?
Kyleena is a T-shaped plastic device that is inserted through the vagina and placed into the uterus by a doctor. The device is usually inserted within 7 days after the start of a menstrual period.
You may feel pain or dizziness during insertion of the IUD. You may also have minor vaginal bleeding. Tell your doctor if you still have these symptoms longer than 30 minutes.
The levonorgestrel device should not interfere with sexual intercourse, wearing tampons, or using other vaginal medications.
After each menstrual period, make sure you can still feel the removal strings. Wash your hands with soap and water, and insert your clean fingers into the vagina. You should be able to feel the strings at the opening of your cervix. Call your doctor at once if you cannot feel the strings, or if you think the device has slipped lower in your uterus or out of your uterus. A sudden increase in menstrual flow may be a sign that the device has slipped out of place.
If you think the device is not properly in place, use a non-hormone method of birth control (condom, or diaphragm with spermicide) to prevent pregnancy until your doctor is able to replace the IUD.
Your doctor will need to see you within a few weeks after insertion of the device to make sure it is still in place correctly. You will also need regular annual pelvic exams and Pap smears.
You may have irregular periods during the first 3 to 6 months of use. Your flow may be lighter or heavier, and you may eventually stop having periods after several months. Call your doctor if you miss a period or think you might be pregnant.
If you need to have an MRI (magnetic resonance imaging), tell your caregivers ahead of time that you have an IUD in place.
Your device may be removed at any time you decide to stop using birth control. The Mirena or Kyleena intrauterine system must be removed at the end of the 5-year wearing time. The Skyla device must be removed after 3 years. The Liletta device must be removed after 6 years. Your doctor can insert a new device at that time if you wish to continue using this form of birth control. Only your doctor should remove the IUD. Do not attempt to remove the device yourself.
If you wish to continue preventing pregnancy, you may need to start using another birth control method a week before your Kyleena is removed.
What happens if I miss a dose?
Since the IUD continuously releases a low dose of levonorgestrel, missing a dose does not occur when using this form of levonorgestrel.
What happens if I overdose?
An overdose of levonorgestrel released from the intrauterine system is very unlikely to occur.
What should I avoid while using Kyleena?
Avoid having more than one sexual partner. The IUD can increase your risk of developing a serious pelvic infection, which is often caused by sexually transmitted disease. Kyleena will not protect you from sexually transmitted diseases, including HIV and AIDS. Using a condom is the only way to help protect yourself from these diseases.
Call your doctor if your sexual partner develops HIV or a sexually transmitted disease, or if you have any change in sexual relationships.
Kyleena side effects
Get emergency medical help if you have severe pain in your lower stomach or side. This could be a sign of a tubal pregnancy (a pregnancy that implants in the fallopian tube instead of the uterus). A tubal pregnancy is a medical emergency.
The levonorgestrel IUD may become embedded into the wall of the uterus, or may perforate (form a hole) in the uterus. If this occurs, the device may no longer prevent pregnancy, or it may move outside the uterus and cause scarring, infection, or damage to other organs. Your doctor may need to surgically remove the device.
Call your doctor at once if you have:
severe cramps or pelvic pain, pain during sexual intercourse;
extreme dizziness or light-headed feeling;
severe migraine headache;
heavy or ongoing vaginal bleeding, vaginal sores, vaginal discharge that is watery, foul-smelling discharge, or otherwise unusual;
pale skin, weakness, easy bruising or bleeding, fever, chills, or other signs of infection;
sudden numbness or weakness (especially on one side of the body), confusion, problems with vision, sensitivity to light;
jaundice (yellowing of the skin or eyes); or
signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Common side effects may include:
pelvic pain, vaginal itching or infection, irregular menstrual periods, changes in bleeding patterns or flow;
stomach pain, nausea, vomiting, bloating;
headache, depression, mood changes;
back pain, breast tenderness or pain;
weight gain, acne, changes in hair growth, loss of interest in sex; or
puffiness in your face, hands, ankles, or feet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Kyleena?
Other drugs may interact with levonorgestrel, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
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Reference from: https://www.drugs.com/mtm/kyleena.html