Hyphed (Oral)

29/03/2020

295

Hovevn Health chia sẻ các bài viết về: Hyphed (uống), tác dụng phụ – liều lượng, Hyphed (uống) điều trị bệnh gì. Các vấn đề lưu ý khác. Vui lòng tham khảo các chi tiết dưới đây.

Tên chung: hydrocodone, chlorpheniramine và pseudoephedrine (Đường uống)

hye-droe-KOE-by by-TAR-trate, klor-fen-IR-a-meen MAL-ee-ate, soo-doe-e-Fed-rin hye-droe-KLOR-ide

Đường uống (Giải pháp)

Cảnh báo: Nghiện, lạm dụng và lạm dụng; suy hô hấp đe dọa tính mạng; nuốt phải vô tình; lỗi thuốc; tương tác cytochrom P450 3A4; sử dụng đồng thời với các thuốc nhóm benzodiazepin hoặc thuốc ức chế thần kinh trung ương khác; tương tác với rượu; Hội chứng cai nghiện opioid ở trẻ sơ sinh Nghiện, lạm dụng và sử dụng sai cách Dự trữ hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride để sử dụng ở những bệnh nhân trưởng thành mà những lợi ích của việc giảm ho được dự kiến sẽ lớn hơn những rủi ro, và trong đó đánh giá đầy đủ về nguyên nhân của ho đã được thực hiện. Đánh giá nguy cơ của từng bệnh nhân trước khi kê toa hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride, kê toa hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride trong thời gian ngắn nhất phù hợp với từng bệnh nhân, theo dõi bệnh nhân. và chỉ nạp lại sau khi đánh giá lại nhu cầu tiếp tục điều trị. Suy hô hấp đe dọa trầm cảm Có thể xảy ra trầm cảm, đe dọa tính mạng hoặc gây tử vong khi sử dụng hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride. Theo dõi tình trạng suy hô hấp, đặc biệt là khi bắt đầu sử dụng hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride hoặc khi sử dụng ở những bệnh nhân có nguy cơ cao hơn. Nuốt phải vô tình Việc nuốt phải một liều hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride, đặc biệt là ở trẻ em, có thể dẫn đến việc sử dụng quá liều hydrocodone. . Lỗi liều có thể dẫn đến quá liều và tử vong do tai nạn. Luôn luôn sử dụng một thiết bị đo mililit chính xác khi đo và sử dụng hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride.Cytochrom P45034 , có thể làm tăng hoặc kéo dài tác dụng phụ của thuốc và có thể gây ức chế hô hấp có thể gây tử vong. Ngoài ra, việc ngừng sử dụng thuốc cảm ứng cytochrom P450 3A4 được sử dụng đồng thời có thể dẫn đến sự gia tăng nồng độ trong huyết tương hydrocodone. Tránh sử dụng hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride ở những bệnh nhân sử dụng thuốc ức chế CYP3A4 hoặc thuốc gây cảm ứng. suy hô hấp, hôn mê và tử vong. Tránh sử dụng hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride ở những bệnh nhân dùng thuốc benzodiazepin, thuốc ức chế thần kinh trung ương khác hoặc rượu. Tương tác với Rượu Hướng dẫn bệnh nhân không tiêu thụ đồ uống có cồn hoặc sử dụng các sản phẩm theo toa hoặc không theo toa có chứa rượu trong khi dùng hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride. Việc sử dụng rượu cùng với hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride có thể dẫn đến tăng nồng độ trong huyết tương và quá liều hydrocodone có thể gây tử vong cho phụ nữ. Việc sử dụng kéo dài hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride trong khi mang thai có thể dẫn đến hội chứng cai nghiện opioid ở trẻ sơ sinh, có thể đe dọa đến tính mạng nếu không được nhận biết và điều trị, và cần được quản lý theo các phác đồ được phát triển bởi các chuyên gia sơ sinh. Nếu hydrocodone bitartrate / chlorpheniramine maleate / pseudoephedrine hydrochloride được sử dụng trong một thời gian dài ở phụ nữ mang thai, khuyên bệnh nhân về nguy cơ mắc hội chứng cai nghiện opioid ở trẻ sơ sinh và đảm bảo sẽ có phương pháp điều trị thích hợp.

Holevn.org xem xét y tế. Cập nhật lần cuối vào ngày 28 tháng 6 năm 2019.

Tên thương hiệu thường được sử dụng

Tại Hoa Kỳ

Hydron PSC
Hyphed
Công chứng
Zutripro

Ở Canada

Vasofrinic Dh

Các dạng bào chế có sẵn:

Giải pháp

Lớp trị liệu: Kết hợp chống ho, Opioid / Antihistamine / Decongestant

Lớp dược lý: Clorpheniramine

Lớp hóa học: Hydrocodone

Sử dụng cho Hyphed

Sự kết hợp hydrocodone, chlorpheniramine và pseudoephedrine được sử dụng để làm giảm ho và nghẹt mũi liên quan đến dị ứng cảm lạnh thông thường.

Hydrocodone là một chất chống nôn gây nghiện (thuốc giảm ho). Nó tác động trực tiếp lên trung tâm ho trong não để giảm ho. Clorpheniramine là thuốc kháng histamine, được sử dụng để làm giảm hoặc ngăn ngừa các triệu chứng dị ứng. Pseudoephedrine là một thuốc thông mũi, làm giảm nghẹt mũi bằng cách thu hẹp các mạch máu và giảm lưu lượng máu đến đường mũi.

Khi hydrocodone được sử dụng trong một thời gian dài, nó có thể trở thành thói quen, gây ra sự phụ thuộc về tinh thần hoặc thể chất. Tuy nhiên, những người tiếp tục ho và nghẹt mũi không nên để nỗi sợ phụ thuộc khiến họ không sử dụng ma túy để giảm ho. Sự phụ thuộc tinh thần (nghiện) không có khả năng xảy ra khi ma túy được sử dụng cho mục đích này. Sự phụ thuộc về thể chất có thể dẫn đến tác dụng phụ khi rút thuốc nếu ngừng điều trị đột ngột. Tuy nhiên, tác dụng phụ nghiêm trọng khi cai thuốc thường có thể được ngăn chặn bằng cách giảm dần liều trong một khoảng thời gian trước khi ngừng điều trị hoàn toàn.

Thuốc này chỉ có sẵn với toa thuốc của bác sĩ.

Trước khi sử dụng Hyphed

Khi quyết định sử dụng thuốc, rủi ro của việc dùng thuốc phải được cân nhắc với lợi ích mà nó sẽ làm. Đây là một quyết định mà bạn và bác sĩ của bạn sẽ đưa ra. Đối với thuốc này, cần xem xét những điều sau đây:

Dị ứng

Measure the oral liquid correctly using the marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Ask your pharmacist for instructions for measuring the correct dose of this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (solution):
- For relief of cough, sneezing, or runny or stuffy nose:
  - Adults—5 milliliters (mL) every 4 to 6 hours as needed. However, the dose is usually not more than 4 doses (20 mL) in 24 hours.
  - Children—Use is not recommended.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm

Precautions while using Hyphed

It is very important that your doctor check your progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your cough does not improve or if it gets worse within 5 days, call your doctor.

Do not use this medicine if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.

If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Symptoms of an overdose include: extreme dizziness or weakness, trouble breathing, slow heartbeat or breathing, seizures, and cold, clammy skin. In case of an overdose, call your doctor right away.

This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using this medicine.

Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.

Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.

This medicine may cause adrenal insufficiency. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.

If you are especially sensitive to the effects of this medicine, do not suddenly stop using it without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping.

Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using this medicine if you plan to have children.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Hyphed side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Fainting
lightheadedness
shakiness in the legs, arms, hands, or feet
trembling or shaking of the hands or feet
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Incidence not known

Bloating
blurred vision
bulging soft spot on the head of an infant
change in the ability to see colors, especially blue or yellow
confusion
constipation
decrease in the frequency of urination
decrease in the urine volume
diarrhea
difficult or troubled breathing
difficulty in passing urine (dribbling)
dizziness
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
drowsiness
fast, slow, or irregular heartbeat
headache
hives or welts, itching, skin rash
irregular, fast or slow, or shallow breathing
loss of appetite
loss of consciousness
nervousness
painful urination
pale or blue lips, fingernails, or skin
pounding in the ears
seizures
sore throat
spasm of the throat
stomach cramps or pain
sweating
tightness of the chest
vomiting
yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

Deep or fast breathing with dizziness
disturbed color perception
double vision
dry mouth
false or unusual sense of well-being
fear or nervousness
halos around lights
nausea
night blindness
numbness of the feet, hands, and around the mouth
overbright appearance of lights
relaxed and calm feeling
restlessness
sleepiness or unusual drowsiness
trouble sleeping
tunnel vision

Incidence not known

Belching
bigger, dilated, or enlarged pupils (black part of the eye)
bloating
change in color vision
chills
cold sweats
continuing ringing or buzzing or other unexplained noise in the ears
cool, pale skin
darkened urine
depression
difficulty seeing at night
feeling of constant movement of self or surroundings
fever
flushing or redness of the skin
full feeling
hearing loss
heartburn
increased appetite
increased hunger
increased in sexual ability, desire, drive, or performance
increased interest in sexual intercourse
increased sensitivity of the eyes to sunlight
increased sweating
indigestion
nightmares
pains in the stomach, side, or abdomen, possibly radiating to the back
pressure in the stomach
sensation of spinning
slurred speech
stomach discomfort or upset
sugar in the urine
swelling of the abdominal or stomach area
swelling of the breasts or breast soreness in both females and males
unusually warm skin
watering of the eyes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Further information

Medical Disclaimer

Reference from: https://www.drugs.com/cons/hyphed.html

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Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Ethanol
Grapefruit Juice

Proper use of Hyphed

This section provides information on the proper use of a number of products that contain hydrocodone, chlorpheniramine, and pseudoephedrine. It may not be specific to Hyphed. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Dosing

For oral dosage form (solution):
- For relief of cough, sneezing, or runny or stuffy nose:
  - Adults—5 milliliters (mL) every 4 to 6 hours as needed. However, the dose is usually not more than 4 doses (20 mL) in 24 hours.
  - Children—Use is not recommended.

Missed dose

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using Hyphed

Do not use this medicine if you have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.

This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using this medicine if you plan to have children.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Hyphed side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Fainting
lightheadedness
shakiness in the legs, arms, hands, or feet
trembling or shaking of the hands or feet
unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness

Incidence not known

Bloating
blurred vision
bulging soft spot on the head of an infant
change in the ability to see colors, especially blue or yellow
confusion
constipation
decrease in the frequency of urination
decrease in the urine volume
diarrhea
difficult or troubled breathing
difficulty in passing urine (dribbling)
dizziness
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
drowsiness
fast, slow, or irregular heartbeat
headache
hives or welts, itching, skin rash
irregular, fast or slow, or shallow breathing
loss of appetite
loss of consciousness
nervousness
painful urination
pale or blue lips, fingernails, or skin
pounding in the ears
seizures
sore throat
spasm of the throat
stomach cramps or pain
sweating
tightness of the chest
vomiting
yellow eyes or skin

More common

Deep or fast breathing with dizziness
disturbed color perception
double vision
dry mouth
false or unusual sense of well-being
fear or nervousness
halos around lights
nausea
night blindness
numbness of the feet, hands, and around the mouth
overbright appearance of lights
relaxed and calm feeling
restlessness
sleepiness or unusual drowsiness
trouble sleeping
tunnel vision

Incidence not known

Belching
bigger, dilated, or enlarged pupils (black part of the eye)
bloating
change in color vision
chills
cold sweats
continuing ringing or buzzing or other unexplained noise in the ears
cool, pale skin
darkened urine
depression
difficulty seeing at night
feeling of constant movement of self or surroundings
fever
flushing or redness of the skin
full feeling
hearing loss
heartburn
increased appetite
increased hunger
increased in sexual ability, desire, drive, or performance
increased interest in sexual intercourse
increased sensitivity of the eyes to sunlight
increased sweating
indigestion
nightmares
pains in the stomach, side, or abdomen, possibly radiating to the back
pressure in the stomach
sensation of spinning
slurred speech
stomach discomfort or upset
sugar in the urine
swelling of the abdominal or stomach area
swelling of the breasts or breast soreness in both females and males
unusually warm skin
watering of the eyes

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

Further information

Medical Disclaimer

Reference from: https://www.drugs.com/cons/hyphed.html

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