Thuốc Helidac (Oral)

28/03/2020

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Holevn Health share articles about :Thuốc Helidac (Oral) , side effects – dosage , Thuốc Helidac (Oral) what disease treatment.Other noted issues. Please refer to the details below.

Generic Name: bismuth subsalicylate, metronidazole, and tetracycline (Oral route)

BIZ-muth sub-sa-LIS-i-late, met-roe-NYE-da-zole, tet-ra-SYE-kleen hye-droe-KLOR-ide

Oral route(Kit)

Metronidazole has been shown to be carcinogenic in mice and rats. Unnecessary use of the drug should be avoided .

Medically reviewed by Holevn.org. Last updated on Oct 17, 2019.

Commonly used brand name(s)

In the U.S.

Helidac

Available Dosage Forms:

Tablet, Chewable
Tablet
Capsule

Uses for Helidac

Bismuth subsalicylate, metronidazole, and tetracycline combination is used together with an H2-receptor antagonist to treat duodenal ulcers caused by H. pylori bacteria.

This package contains a combination of 3 different medicines. The individual medicines contained in this package should not be used alone or for other purposes than to treat duodenal ulcers caused by H. pylori.

This combination of medicines is available only with your doctor’s prescription.

Before using Helidac

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Appropriate studies have not been performed on the relationship of age to the effects of Helidac® in the pediatric population. Safety and efficacy have not been established.

Tetracycline may cause permanent discoloration of the teeth and slow down the growth of bones. This medicine should not be given to children 8 years of age and younger unless directed by the child’s doctor.

Geriatric

Although appropriate studies on the relationship of age to the effects of Helidac® therapy have not been performed in the geriatric population, no geriatric-specific problems have been documented to date. However, elderly patients are more likely to have age-related kidney, liver, or heart problems, which may require caution and an adjustment in the dose for patients receiving Helidac®.

Pregnancy

Pregnancy Category	Explanation
All Trimesters	D	Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.

Breastfeeding

Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.

Interactions with medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.

Acitretin
Amisulpride
Amprenavir
Bepridil
Cisapride
Disulfiram
Dronabinol
Dronedarone
Mesoridazine
Methoxyflurane
Pimozide
Saquinavir
Sparfloxacin
Terfenadine
Thioridazine
Ziprasidone

Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aceclofenac
Acemetacin
Alfuzosin
Amiodarone
Amitriptyline
Amoxicillin
Ampicillin
Amtolmetin Guacil
Anagrelide
Apomorphine
Aripiprazole
Aripiprazole Lauroxil
Arsenic Trioxide
Asenapine
Astemizole
Atazanavir
Azithromycin
Bacampicillin
Balsalazide
Bedaquiline
Bexarotene
Bromfenac
Bufexamac
Buprenorphine
Bupropion
Buserelin
Busulfan
Capecitabine
Celecoxib
Ceritinib
Chloroquine
Chlorpromazine
Cholera Vaccine, Live
Choline Magnesium Trisalicylate
Choline Salicylate
Ciprofloxacin
Citalopram
Clarithromycin
Clofazimine
Clomipramine
Clonixin
Cloxacillin
Clozapine
Crizotinib
Cyclobenzaprine
Dabrafenib
Dasatinib
Degarelix
Delamanid
Desipramine
Deslorelin
Deutetrabenazine
Dexibuprofen
Dexketoprofen
Dicloxacillin
Diflunisal
Digoxin
Dipyrone
Disopyramide
Dofetilide
Dolasetron
Domperidone
Donepezil
Doxepin
Doxifluridine
Droperidol
Droxicam
Ebastine
Efavirenz
Encorafenib
Entrectinib
Eribulin
Erythromycin
Escitalopram
Etodolac
Etofenamate
Etoricoxib
Etretinate
Famotidine
Felbamate
Felbinac
Fenoprofen
Fepradinol
Feprazone
Fingolimod
Flecainide
Floctafenine
Fluconazole
Flufenamic Acid
Fluorouracil
Fluoxetine
Flurbiprofen
Formoterol
Foscarnet
Fosphenytoin
Galantamine
Gatifloxacin
Gemifloxacin
Glasdegib
Gonadorelin
Goserelin
Granisetron
Halofantrine
Haloperidol
Histrelin
Hydroquinidine
Hydroxychloroquine
Hydroxyzine
Ibuprofen
Ibutilide
Iloperidone
Imipramine
Inotuzumab Ozogamicin
Isotretinoin
Itraconazole
Ivabradine
Ivosidenib
Ketoconazole
Ketoprofen
Lapatinib
Leuprolide
Levofloxacin
Lofexidine
Lornoxicam
Loxoprofen
Lumefantrine
Lumiracoxib
Macimorelin
Magnesium Salicylate
Mebendazole
Meclofenamate
Mefenamic Acid
Mefloquine
Meloxicam
Mesalamine
Methadone
Methicillin
Mifepristone
Mizolastine
Morniflumate
Moxifloxacin
Mycophenolate Mofetil
Mycophenolic Acid
Nabumetone
Nafarelin
Nafcillin
Naproxen
Nelfinavir
Nepafenac
Niflumic Acid
Nilotinib
Nimesulide
Nimesulide Beta Cyclodextrin
Norfloxacin
Octreotide
Ofloxacin
Olanzapine
Olsalazine
Ondansetron
Osimertinib
Oxacillin
Oxaprozin
Oxyphenbutazone
Paliperidone
Panobinostat
Papaverine Hydrochloride
Parecoxib
Paroxetine
Pasireotide
Pazopanib
Penicillin G
Penicillin G Benzathine
Penicillin G Procaine
Penicillin V
Pentamidine
Perphenazine
Phenylbutazone
Phenyl Salicylate
Piketoprofen
Pimavanserin
Pipamperone
Piperacillin
Piroxicam
Pitolisant
Pivampicillin
Posaconazole
Probucol
Procainamide
Prochlorperazine
Proglumetacin
Promethazine
Propafenone
Propyphenazone
Proquazone
Protriptyline
Quetiapine
Quinidine
Quinine
Ranolazine
Ribociclib
Risperidone
Ritonavir
Rofecoxib
Salicylamide
Salicylic Acid
Salsalate
Sertindole
Sertraline
Sevoflurane
Siponimod
Sodium Phosphate
Sodium Phosphate, Dibasic
Sodium Phosphate, Monobasic
Sodium Salicylate
Solifenacin
Sorafenib
Sotalol
Sulfasalazine
Sulindac
Sulpiride
Sultamicillin
Sunitinib
Tacrolimus
Tamoxifen
Tegafur
Telaprevir
Telavancin
Telithromycin
Temocillin
Tenoxicam
Tetrabenazine
Tiaprofenic Acid
Tizanidine
Tolfenamic Acid
Tolmetin
Tolterodine
Toremifene
Trazodone
Tretinoin
Trimipramine
Triptorelin
Trolamine Salicylate
Valdecoxib
Vandetanib
Vardenafil
Vemurafenib
Venlafaxine
Vilanterol
Vinflunine
Voriconazole
Vorinostat
Warfarin
Zuclopenthixol

Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.

Aluminum Carbonate, Basic
Aluminum Hydroxide
Aluminum Phosphate
Aminolevulinic Acid
Atovaquone
Calcium
Carbamazepine
Cholestyramine
Colestipol
Cyclosporine
Dihydroxyaluminum Aminoacetate
Dihydroxyaluminum Sodium Carbonate
Doxycycline
Iron
Lithium
Magaldrate
Magnesium Carbonate
Magnesium Hydroxide
Magnesium Oxide
Magnesium Trisilicate
Milk Thistle
Omadacycline
Probenecid
Quinine
Sulfinpyrazone
Tamarind

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is not recommended. Your doctor may decide not to treat you with this medication, change some of the other medicines you take, or give you special instructions about the use of food, alcohol, or tobacco.

Ethanol

Using this medicine with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

Dairy Food

Proper use of Helidac

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Helidac® comes with patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.

Each day’s therapy is packaged in a blister card that contains 8 chewable tablets of bismuth subsalicylate, 4 tablets of metronidazole, and 4 capsules of tetracycline.

Pay attention to how to take each medicine. Completely chew and swallow 2 bismuth tablets. Swallow the metronidazole tablets and tetracycline capsules with a full glass of water. This will help prevent irritation of the esophagus (tube between the throat and stomach). Do not chew, crush, or break the metronidazole tablets and tetracycline capsules.

Your doctor will also prescribe another medicine, a histamine H2 receptor antagonist, which will come with its own directions and must be taken along with this combination of medicines.

Avoid taking milk, dairy products, antacids containing aluminum, calcium, or magnesium (e.g., Maalox®, Tums®), or supplements containing iron, zinc, or sodium bicarbonate. This may keep tetracycline from working properly.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop taking this medicine too soon, your symptoms may return.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (blister card containing chewable tablets, tablets, and capsules):
- For treatment of duodenal ulcers caused by H. pylori infection:
  - Adults—One dose (525 milligrams [mg] of bismuth subsalicylate, 250 mg of metronidazole, and 500 mg of tetracycline) four times a day, taken with meals and at bedtime, for 14 days.
  - Children—Use and dose must be determined by your doctor.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

If you miss more than four doses of this combination of medicines, check with your doctor.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions while using Helidac

If your condition does not improve or if it becomes worse, check with your doctor.

Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. Your birth control pills may not work as well while you are using this medicine. If you think you have become pregnant while using this medicine, tell your doctor right away.

Do not take this medicine if you are also using disulfiram (Antabuse®) or methoxyflurane (Penthrane®).

Drinking alcoholic beverages while taking metronidazole may cause stomach pain, nausea, vomiting, headache, or flushing or redness of the face. Other alcohol-containing preparations (e.g., elixirs, cough syrups, tonics) may also cause problems. Do not drink alcoholic beverages or take other products containing propylene glycol while you are taking Helidac® and for at least 3 days after stopping it.

Metronidazole may cause some people to become dizzy, clumsy, or trouble seeing clearly.

Children or teenagers who have or who are recovering from chickenpox or influenza should not use this combination of medicines unless directed by the child’s doctor. If nausea or vomiting occurs after taking this combination of medicines, check with the child’s doctor.

Tetracycline may cause your skin to be more sensitive to sunlight than it is normally. Exposure to sunlight, even for brief periods of time, may cause a skin rash, itching, redness or other discoloration of the skin, or a severe sunburn. When you begin taking tetracycline:

Stay out of direct sunlight, especially between the hours of 10:00 a.m. and 3:00 p.m., if possible.
Wear protective clothing, including a hat. Also, wear sunglasses.
Apply a sunblock product that has a skin protection factor (SPF) of at least 15. Some patients may require a product with a higher SPF, especially if they have a fair complexion. If you have any questions about this, check with your doctor.
Apply a sunblock lipstick that has an SPF of at least 15 to protect your lips.
Do not use a sunlamp or tanning bed or booth.

You may still be more sensitive to sunlight or sunlamps for 2 weeks to several months or more after stopping tetracycline. If you have a severe reaction, check with your doctor.

Bismuth subsalicylate may cause dark tongue and/or black stools. This is only temporary and will go away after you stop taking this medicine.

This medicine lowers the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. Avoid people who are sick. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.

If you develop a skin rash, hives, or any allergic reaction to this medicine, stop taking the medicine and check with your doctor as soon as possible.

Before having surgery (including dental surgery) with a general anesthetic, tell the medical doctor or dentist in charge that you are taking tetracycline in this combination of medicines.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Helidac side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

Abdominal or stomach pain
bloody or black, tarry stools
diarrhea
nausea

Less common

Burning, prickling, or tingling sensations
dizziness
vomiting

Rare

Bloody vomit
convulsions (seizures)
fainting
heart attack
irritation of the mouth or tongue
joint pain and swelling
sensitivity of the skin to sunlight
skin rash
trouble with swallowing

Get emergency help immediately if any of the following symptoms of overdose occur:

Symptoms of overdose

Clumsiness or unsteadiness
confusion
continuing ringing or buzzing in ears
fast heartbeat
fast or deep breathing
fever
pain, numbness, or tingling in the arms, legs, hands, or feet
unusual tiredness
vomiting

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common or rare

Burning or itching around the anus
constipation
general feeling of discomfort or illness
loss of appetite
nervousness
trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

Medical Disclaimer

The content of Holevn is solely for the purpose of providing information about Thuốc Helidac (Oral) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/helidac.html

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