Thuốc Guselkumab

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Thuốc Guselkumab
Thuốc Guselkumab

Holevn Health share articles about :Thuốc Guselkumab  , side effects – dosage , Thuốc Guselkumab what disease treatment.Other noted issues. Please refer to the details below.

Generic Name: guselkumab (GUE sel KOO mab)
Brand Name:Tremfya, Tremfya One-Press

Medically reviewed by Holevn.org on Jan 28, 2020 – Written by Cerner Multum

What is guselkumab?

Guselkumab is used to treat moderate to severe plaque psoriasis in adults.

Guselkumab may also be used for purposes not listed in this medication guide.

Important Information

Guselkumab can weaken (suppress) your immune system, and you may get an infection more easily.

Call your doctor if you have signs of infection such as fever, sweats, chills, muscle aches, weight loss, diarrhea, stomach cramps, pain or burning when you urinate, cough (may contain blood or mucus), shortness of breath, or skin sores that look different from psoriasis.

Before taking this medicine

You should not use guselkumab if you are allergic to guselkumab or Polysorbate 80.

Tell your doctor if you have ever had tuberculosis or if anyone in your household has tuberculosis. Also tell your doctor if you have recently traveled. Tuberculosis and some fungal infections are more common in certain parts of the world, and you may have been exposed during travel.

Before you start treatment with guselkumab, your doctor may perform tests to make sure you do not have tuberculosis or other infections.

Tell your doctor if you have ever had:

  • an active or chronic infection;

  • active tuberculosis infection that is not being treated; or

  • if you have recently received or are scheduled to receive any vaccine.

Make sure you are current on all vaccines before you start treatment with guselkumab.

It is not known whether this medicine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

It is not known whether guselkumab passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breastfeeding.

Guselkumab is not approved for use by anyone younger than 18 years old.

How should I use guselkumab?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed.

Guselkumab is injected under the skin. A healthcare provider may teach you how to properly use the medication by yourself.

The first two injections are usually given 4 weeks apart, followed by one injection every 8 weeks. Your doctor will determine how long to treat you with guselkumab.

Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Store in the refrigerator. Protect from light and do not freeze.

Take the medicine out of the refrigerator and allow it to reach room temperature for 30 minutes before injecting your dose. Do not remove the needle cap until you are ready to give the injection.

Do not shake the prefilled syringe. Prepare your dose only when you are ready to give an injection.

Guselkumab should appear clear to light yellow in color. Do not use the medicine if it looks cloudy or has particles in it. Call your pharmacist for new medicine.

Do not inject guselkumab into an active psoriasis lesion. Avoid injecting into skin that is thick, scaly, bruised, red, or tender.

Each single-use prefilled syringe is for one use only. Throw it away after one use, even if there is still medicine left inside.

Use a needle and syringe only once and then place them in a puncture-proof “sharps” container. Follow state or local laws about how to dispose of this container. Keep it out of the reach of children and pets.

What happens if I miss a dose?

Use the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not use two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call 115.

What should I avoid while using guselkumab?

Do not receive a “live” vaccine while using guselkumab. The vaccine may not work as well and may not fully protect you from disease. Live vaccines include measles, mumps, rubella (MMR), rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

Guselkumab side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Guselkumab can weaken (suppress) your immune system, and you may get an infection more easily.

Call your doctor at once if you have signs of infection, such as:

  • fever, chills, body aches, night sweats;

  • weight loss, feeling very tired;

  • cough (may contain blood or mucus), shortness of breath;

  • pain or burning when you urinate;

  • severe diarrhea or stomach cramps; or

  • skin redness, blisters, oozing, or sores that look different from psoriasis.

Common side effects may include:

  • headache, joint pain;

  • diarrhea, stomach pain;

  • cold symptoms such as stuffy nose, sneezing, sore throat;

  • skin infections; or

  • pain, itching, swelling, redness, or bruising where the medicine was injected.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Guselkumab dosing information

Usual Adult Dose for Plaque Psoriasis:

100 mg subcutaneously at Week 0, Week 4, and every 8 weeks thereafter

Comments:
-Evaluate patients for TB prior to initiating therapy.

Use: For the treatment of adults with moderate-to-severe plaque psoriasis who are candidates for systemic therapy or phototherapy

What other drugs will affect guselkumab?

Other drugs may affect guselkumab, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Related questions

The content of Holevn is solely for the purpose of providing information about Thuốc Guselkumab  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/mtm/guselkumab.html

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