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Generic Name: fentanyl (buccal/sublingual) (FEN tan il BUK al / sub LIN gwal)
Brand Names:Abstral, Fentora, Subsys
Medically reviewed by P. Thornton, DipPharm Last updated on Nov 5, 2019.
What is Fentora?
Fentora (fentanyl) is an opioid pain medication. An opioid is sometimes called a narcotic.
Fentora buccal tablets are used to treat “breakthrough” cancer pain that is not controlled by other medicines.
The tablets are used in the mouth but not swallowed whole. The tablet is placed inside the mouth between the cheek and gum (buccal) OR on the floor of your mouth, under your tongue (sublingual).
Fentora is not for treating pain that is not cancer-related.
Fentanyl can slow or stop your breathing, and may be habit-forming. Use only your prescribed dose. Never share Fentora with another person.
MISUSE OF NARCOTIC PAIN MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a child or other person using the medicine without a prescription.
Fatal side effects can occur if you use this medicine with alcohol, or with other drugs that cause drowsiness or slow your breathing.
Before taking this medicine
Do not use Fentora unless you are already using an around-the-clock opioid medicine and are tolerant to it. You should not use Fentora if you are allergic to fentanyl, or if you have:
severe asthma or other breathing problems; or
a stomach or bowel obstruction (including paralytic ileus).
To make sure Fentora is safe for you, tell your doctor if you have ever had:
breathing problems, sleep apnea;
any type of breathing problem or lung disease;
a head injury, brain tumor, or seizures;
low blood pressure, slow heartbeats or other heart rhythm disorder;
drug or alcohol addiction, depression, schizophrenia, or hallucinations;
liver or kidney disease;
urination problems; or
problems with your thyroid, gallbladder, or pancreas.
Tell your doctor if there are children living in the home where you will store this medicine. The amount of fentanyl in this medicine can be fatal to a child.
If you use Fentora while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks. Tell your doctor if you are pregnant or plan to become pregnant.
Do not breast-feed while you are using this medicine.
How should I use Fentora?
Use Fentora exactly as prescribed by your doctor. Follow all directions on your prescription label. Fentanyl can slow or stop your breathing. Never use this medicine in larger amounts, or for longer than prescribed. Tell your doctor if the medicine seems to stop working as well in relieving your pain.
Fentanyl may be habit-forming, even at regular doses. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. MISUSE OF NARCOTIC MEDICINE CAN CAUSE ADDICTION, OVERDOSE, OR DEATH, especially in a person using the medicine without a prescription. Selling or giving away fentanyl is against the law.
Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.
If you have been using another form of fentanyl (injection, skin patch, “lollipop” device), your buccal or sublingual dose may be different.
Do not crush, split, suck, or chew Fentora tablets, or swallow the tablets whole. You will get less relief for your breakthrough cancer pain.
Wait 30 minutes after using Fentora. If there is any of the tablet left in your mouth, you may drink a glass of water to help you swallow the left over medicine.
You can place a Fentora tablet in your mouth above a rear molar tooth between the upper cheek and gum. Switch (alternate) sides of your mouth for each dose. You can also place a tablet on the floor of your mouth, under your tongue. When placing the tablet under your tongue, first lift your tongue, then place the tablet under your tongue and lower your tongue over the tablet.
Use one dose of Fentora for an episode of breakthrough cancer pain.
If your breakthrough cancer pain does not get better 30 minutes after taking the first dose of Fentora, you can use only one more dose as instructed by your healthcare provider. You must not use more than two doses for each episode of breakthrough cancer pain.
If your breakthrough pain does not get better after the second dose of Fentora, call your healthcare provider for instructions. Do not use another dose at this time.
Wait at least 4 hours before treating a new episode of breakthrough cancer pain with Fentora.
If you only need to take one dose of Fentora for an episode of breakthrough pain, you must wait 4 hours from the time of that dose to take a dose for a new episode of breakthrough pain.
If you need to use two doses of Fentora for an episode of breakthrough pain, you must wait 4 hours after the second dose to take a dose for a new episode of breakthrough pain.
It is important for you to keep taking your around-the-clock opioid pain medicine while using Fentora.
Talk to your healthcare provider if your dose of Fentora does not relieve your breakthrough cancer pain. Your healthcare provider will decide if your dose needs to be changed.
Talk to your healthcare provider if you have more than 4 episodes of breakthrough cancer pain per day. The dose of your around-the-clock opioid pain medicine may need to be adjusted.
If you begin to feel dizzy, sick to your stomach, or very sleepy before the tablet is completely dissolved, rinse your mouth with water and spit the remaining pieces of the tablet into a sink or toilet right away. Rinse the sink or flush the toilet to dispose of any remaining tablet pieces.
If you use too much Fentora or overdose, you or your caregiver should call for emergency medical help or have someone take you to the nearest hospital emergency room.
Do not stop using fentanyl suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to safely stop using fentanyl.
Never crush or break a Fentora tablet to inhale the powder or mix it into a liquid to inject the drug into your vein.
Store at room temperature away from moisture and heat. Do not freeze. Keep your medicine in a place where others cannot get to it. Keep track of the amount of medicine used from each new bottle. Fentanyl is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.
Keep this medicine out of the reach of children or pets. The amount of fentanyl in each Fentora tablet can be fatal to a child or pet who accidentally sucks on or swallows it. Seek emergency medical attention if this happens.
Do not keep leftover opioid medication. Just one dose can cause death in someone using this medicine accidentally or improperly.
Carefully follow disposal instructions when Fentora is no longer needed. Ask your pharmacist where to locate a drug take-back disposal program. If there is no take-back program, throw away any unused fentanyl tablets by removing them from the blister pack and flushing them down a toilet.
What happens if I miss a dose?
Since Fentora is used for pain, you are not likely to miss a dose. Skip any missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call 115. A fentanyl overdose can be fatal, especially in a child or other person using the medicine without a prescription. Overdose symptoms may include extreme weakness or drowsiness, weak pulse, cold and clammy skin, pinpoint pupils, and slow breathing (breathing may stop).
What should I avoid while using Fentora?
This medicine may impair your thinking or reactions. Avoid driving or operating machinery until you know how Fentora will affect you. Dizziness or severe drowsiness can cause falls or other accidents.
Do not drink alcohol. Dangerous side effects or death could occur.
Grapefruit and grapefruit juice may interact with fentanyl and lead to unwanted side effects. Avoid the use of grapefruit products while taking Fentora.
Fentora side effects
Get emergency medical help if you have signs of an allergic reaction to Fentora: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Like other narcotic medicines, fentanyl can slow your breathing. Death may occur if breathing becomes too weak. A person caring for you should seek emergency medical attention if you have slow breathing with long pauses, blue colored lips, or if you are hard to wake up.
Call your doctor at once if you have:
slow heart rate, sighing, shallow breathing, breathing that stops during sleep;
severe drowsiness, feeling like you might pass out;
confusion, extreme fear, unusual thoughts or behavior; or
low cortisol levels – nausea, vomiting, loss of appetite, dizziness, worsening tiredness or weakness.
Seek medical attention right away if you have symptoms of serotonin syndrome, such as: agitation, hallucinations, fever, sweating, shivering, fast heart rate, muscle stiffness, twitching, loss of coordination, nausea, vomiting, or diarrhea.
Serious side effects may be more likely in older adults and those who are malnourished or debilitated.
Long-term use of opioid medication may affect fertility (ability to have children) in men or women. It is not known whether opioid effects on fertility are permanent.
Common Fentora side effects may include:
headache, dizziness, drowsiness, pale skin, feeling weak or tired;
constipation, nausea, vomiting; or
swelling in your hands or feet.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Fentora?
Some drugs can raise or lower your blood levels of fentanyl, which may cause side effects or make Fentora less effective. Tell your doctor if you also use certain antibiotics, antifungal medications, heart or blood pressure medications, or medicines to treat HIV or AIDS.
Fentanyl can interact with many other drugs and cause dangerous side effects or death. Be sure your doctor knows if you also use:
cold or allergy medicines, bronchodilator asthma/COPD medication, or a diuretic (“water pill”);
medicines for motion sickness, irritable bowel syndrome, or overactive bladder;
other narcotic medications – opioid pain medicine or prescription cough medicine;
a sedative like Valium – diazepam, alprazolam, lorazepam, Xanax, Klonopin, Versed, and others;
drugs that make you sleepy or slow your breathing – a sleeping pill, muscle relaxer, medicine to treat mood disorders or mental illness; or
drugs that affect serotonin levels in your body – a stimulant, or medicine for depression, Parkinson’s disease, migraine headaches, serious infections, or nausea and vomiting.
This list is not complete. Other drugs may interact with fentanyl, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Fentora only for the indication prescribed.
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The content of Holevn is solely for the purpose of providing information about Thuốc Fentora and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/fentora.html
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