Thuốc Etoposide

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Thuốc Etoposide
Thuốc Etoposide

Hovevn Health chia sẻ các bài viết về: Thuốc Etoposide, tác dụng phụ – liều lượng, Thuốc Etoposide điều trị bệnh gì. Các vấn đề lưu ý khác. Vui lòng tham khảo các chi tiết dưới đây.

e-TOE-poe-side

Đường truyền tĩnh mạch (Giải pháp)

Suy tủy nghiêm trọng với kết quả là nhiễm trùng hoặc chảy máu có thể xảy ra với etoposide.

Holevn.org xem xét y tế. Cập nhật lần cuối vào ngày 26 tháng 1 năm 2020.

Tên thương hiệu thường được sử dụng

Tại Hoa Kỳ

  • Bạch cầu
  • Vepesid

Ở Canada

  • Dom-Etoposide
  • Eposein
  • Etoposide
  • Pms-Etoposide

Các dạng bào chế có sẵn:

  • Giải pháp
  • Bột giải pháp

Lớp trị liệu: Chất chống ung thư

Lớp dược lý: Thuốc ức chế phân bào

Sử dụng cho etoposide

Tiêm Etoposide (còn được gọi là VP-16) được sử dụng kết hợp với các loại thuốc trị ung thư khác để điều trị ung thư tinh hoàn và ung thư phổi tế bào nhỏ. Nó cũng đôi khi được sử dụng để điều trị một số loại ung thư khác ở cả nam và nữ.

Etoposide thuộc nhóm thuốc được gọi là thuốc chống ung thư. Cách chính xác mà etoposide hành động chống lại ung thư không được biết đến. Tuy nhiên, nó dường như can thiệp vào sự phát triển của các tế bào ung thư, cuối cùng bị phá hủy. Vì sự tăng trưởng của các tế bào cơ thể bình thường cũng có thể bị ảnh hưởng bởi etoposide, các tác động khác cũng sẽ xảy ra. Một số trong số này có thể nghiêm trọng và phải được báo cáo với bác sĩ của bạn. Các tác động khác, như rụng tóc, có thể không nghiêm trọng nhưng có thể gây lo ngại. Một số tác dụng có thể không xảy ra cho đến vài tháng hoặc nhiều năm sau khi thuốc được sử dụng.

Trước khi bạn bắt đầu điều trị bằng etoposide, bạn và bác sĩ của bạn nên nói về lợi ích của etoposide cũng như những rủi ro khi sử dụng nó.

Etoposide chỉ được cung cấp bởi hoặc dưới sự giám sát của bác sĩ.

Trước khi sử dụng etoposide

Khi quyết định sử dụng thuốc, rủi ro của việc dùng thuốc phải được cân nhắc với lợi ích mà nó sẽ làm. Đây là một quyết định mà bạn và bác sĩ của bạn sẽ đưa ra. Đối với etoposide, những điều sau đây cần được xem xét:

Dị ứng

Hãy cho bác sĩ của bạn nếu bạn đã từng có bất kỳ phản ứng bất thường hoặc dị ứng với etoposide hoặc bất kỳ loại thuốc nào khác. Cũng nói với chuyên gia chăm sóc sức khỏe của bạn nếu bạn có bất kỳ loại dị ứng nào khác, chẳng hạn như thực phẩm, thuốc nhuộm, chất bảo quản hoặc động vật. Đối với các sản phẩm không kê đơn, đọc nhãn hoặc thành phần gói cẩn thận.

Nhi khoa

Các nghiên cứu thích hợp đã không được thực hiện về mối quan hệ của tuổi tác với tác động của việc tiêm etoposide trong dân số nhi khoa. An toàn và hiệu quả chưa được thành lập.

Lão

Using etoposide while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during treatment and for at least 6 months after your last dose. If you think you have become pregnant while using the medicine, tell your doctor right away.

Etoposide may also cause birth defects if the father is using it when his sexual partner becomes pregnant. Men using etoposide should use condoms as a form of birth control during treatment and for at least 4 months after the last dose of etoposide. A man intending to father a child should stop using etoposide and check with his doctor right away.

Etoposide can temporarily lower the number of white blood cells in your blood, increasing the chance of your getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • constipation
  • cracked lips
  • hair loss or thinning of the hair
  • lack or loss of strength
  • swelling or inflammation of the mouth
  • weight loss

Etoposide often causes a temporary loss of hair. After treatment with etoposide has ended, normal hair growth should return.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Etoposide  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/etoposide-oral-intravenous.html

The presence of other medical problems may affect the use of etoposide. Make sure you tell your doctor if you have any other medical problems, especially:

  • Low serum albumin (protein in the blood)—May experience increased side effects.
  • Infection—May decrease your body’s ability to fight infection.
  • Kidney disease—Use with caution. The effects of etoposide may be increased because of slower removal from the body.

Proper use of etoposide

A nurse or other trained health professional will give you etoposide in a hospital or cancer treatment center. Etoposide is given through a needle placed in one of your veins. The medicine must be injected slowly, so your IV tube will need to stay in place for 30 to 60 minutes.

Etoposide is sometimes given together with certain other medicines. If you are using a combination of medicines, make sure that you take each one at the proper time and do not mix them. If you are taking some of these medicines by mouth, ask your doctor to help you plan a way to remember to take your medicines at the right times.

Etoposide often causes nausea, vomiting, and loss of appetite, which may be severe. However, it is very important that you continue to receive the medicine, even if you begin to feel ill. Ask your doctor for ways to lessen these effects.

Precautions while using etoposide

It is very important that your doctor check your progress at regular visits to make sure that etoposide is working properly. Blood tests may be needed to check for unwanted effects.

Using etoposide while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant during treatment and for at least 6 months after your last dose. If you think you have become pregnant while using the medicine, tell your doctor right away.

Etoposide may also cause birth defects if the father is using it when his sexual partner becomes pregnant. Men using etoposide should use condoms as a form of birth control during treatment and for at least 4 months after the last dose of etoposide. A man intending to father a child should stop using etoposide and check with his doctor right away.

Etoposide can temporarily lower the number of white blood cells in your blood, increasing the chance of your getting an infection. It can also lower the number of platelets, which are necessary for proper blood clotting. If this occurs, there are certain precautions you can take, especially when your blood count is low, to reduce the risk of infection or bleeding:

  • If you can, avoid people with infections. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or have painful or difficult urination.
  • Check with your doctor immediately if you notice any unusual bleeding or bruising, black, tarry stools, blood in the urine or stools, or pinpoint red spots on your skin.
  • Be careful when using a regular toothbrush, dental floss, or toothpick. Your medical doctor, dentist, or nurse may recommend other ways to clean your teeth and gums. Check with your medical doctor before having any dental work done.
  • Do not touch your eyes or the inside of your nose unless you have just washed your hands and have not touched anything else in the meantime.
  • Be careful not to cut yourself when you are using sharp objects such as a safety razor or fingernail or toenail cutters.
  • Avoid contact sports or other situations where bruising or injury could occur.

Etoposide may cause serious allergic reactions, including anaphylaxis. Anaphylaxis can be life-threatening and requires immediate medical attention. Tell your doctor or nurse right away if you have chills, fever, lightheadedness, dizziness, or fainting, fast, pounding heartbeat, swelling of the face, tongue, and throat, or trouble breathing after you receive the medicine.

Injection site reactions may occur while you are receiving etoposide. Tell your doctor right away if you notice swelling, pain, or redness at the injection site.

Etoposide may cause leukemia (cancer of the blood or bone marrow) in rare cases. Talk with your doctor about any concerns you have about this.

Talk with your doctor before getting flu shots or other vaccines while you are receiving etoposide because there are certain vaccines that you should not receive.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Etoposide side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur:

More common

  • Black, tarry stools
  • bleeding gums
  • blood in the urine or stools
  • chest pain
  • chills
  • cough
  • fever
  • painful or difficult urination
  • pale skin
  • pinpoint red spots on the skin
  • sore throat
  • sores, ulcers, or white spots on the lips or in the mouth
  • swollen glands
  • troubled breathing with exertion
  • unusual bleeding or bruising
  • unusual tiredness or weakness

Less common

  • Blurred vision
  • confusion
  • cough or hoarseness, accompanied by fever or chills
  • difficulty with swallowing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
  • face is warm or hot to touch
  • fast heartbeat
  • headache
  • hives, itching, or skin rash
  • lower back or side pain, accompanied by fever or chills
  • nervousness
  • numbness or tingling in the fingers or toes
  • pain or redness at the site of injection
  • pale skin at the site of injection
  • pounding in the ears
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • redness to face
  • slow or fast heartbeat
  • sweating
  • tightness in the chest

Rare

  • Back pain
  • difficulty with walking
  • loss of consciousness
  • swelling of the face or tongue
  • tightness in the throat

Incidence not known

  • Abdominal or stomach pain, severe
  • blindness
  • blistering, peeling, or loosening of the skin
  • blue-yellow color blindness
  • dark urine
  • decreased vision
  • eye pain
  • joint or muscle pain
  • loss of appetite
  • nausea or vomiting
  • red, irritated eyes
  • red skin lesions, often with a purple center
  • seizures
  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Bad, unusual, or unpleasant (after) taste
  • change in taste
  • constipation
  • cracked lips
  • hair loss or thinning of the hair
  • lack or loss of strength
  • swelling or inflammation of the mouth
  • weight loss

Etoposide often causes a temporary loss of hair. After treatment with etoposide has ended, normal hair growth should return.

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Etoposide  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/etoposide-oral-intravenous.html

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