Hovevn Health chia sẻ các bài viết về: Thuốc Elotuzumab (Tiêm tĩnh mạch), tác dụng phụ – liều dùng, Thuốc Elotuzumab (Tiêm tĩnh mạch) điều trị bệnh gì. Các vấn đề lưu ý khác. Vui lòng tham khảo các chi tiết dưới đây.
el-oh-TZ-ue-mab
Holevn.org xem xét y tế. Cập nhật lần cuối vào ngày 4 tháng 4 năm 2019.
Tên thương hiệu thường được sử dụng
Tại Hoa Kỳ
- Empliciti
Các dạng bào chế có sẵn:
- Bột giải pháp
Lớp trị liệu: Chất chống ung thư
Lớp dược lý: Kháng thể đơn dòng
Sử dụng cho elotuzumab
Tiêm Elotuzumab được sử dụng cùng với lenalidomide và dexamethasone để điều trị đa u tủy (một loại ung thư tế bào máu) ở những bệnh nhân đã điều trị từ một đến ba lần điều trị ung thư trước đó. Nó cũng được sử dụng cùng với pomalidomide và dexamethasone để điều trị đa u tủy ở những bệnh nhân đã điều trị ít nhất hai lần điều trị ung thư trước đó (ví dụ, lenalidomide, thuốc ức chế proteasome). Elotuzumab can thiệp vào sự phát triển của các tế bào ung thư, sau đó bị cơ thể phá hủy. Nó là một chất chống ung thư (thuốc trị ung thư).
Elotuzumab chỉ được cung cấp bởi hoặc dưới sự giám sát trực tiếp của bác sĩ.
Trước khi sử dụng elotuzumab
Khi quyết định sử dụng thuốc, rủi ro của việc dùng thuốc phải được cân nhắc với lợi ích mà nó sẽ làm. Đây là một quyết định mà bạn và bác sĩ của bạn sẽ đưa ra. Đối với elotuzumab, cần xem xét những điều sau đây:
Dị ứng
- Blurred vision
- body aches or pain
- chest pain
- chills
- clay-colored stools
- confusion
- cough
- dark urine
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- ear congestion
- fever
- headache
- hives, itching, skin rash
- hoarseness
- irritation
- joint pain, stiffness, or swelling
- loss of appetite
- loss of voice
- lower back or side pain
- nasal congestion
- nausea
- nervousness
- painful or difficult urination
- persistent sore that does not heal
- pink skin growth
- pounding in the ears
- reddish patch or irritated area
- redness of the skin
- runny nose
- shiny skin bump
- slow or fast heartbeat
- sneezing
- sore throat
- stomach pain or tenderness
- stuffy nose
- sweating
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- troubled breathing or swallowing
- unusual tiredness or weakness
- vomiting
- white, yellow or waxy scar-like area on the skin
- yellow eyes or skin
Less common
- Agitation
- anxiety
- decreased awareness or responsiveness
- decreased urine output
- depression
- dizziness or lightheadedness
- fainting
- fast heartbeat
- hostility
- irritability
- loss of consciousness
- muscle twitching
- pale skin
- rapid weight gain
- seizures
- severe sleepiness
- troubled breathing with exertion
- unusual bleeding or bruising
- unusual drowsiness, dullness, or feeling of sluggishness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Blindness
- burning, numbness, tingling, or painful sensations
- decreased appetite
- decreased vision
- decreased weight
- diarrhea
- difficulty having a bowel movement
- muscle aches
- night sweats
- pain in the arms or legs
- unsteadiness or awkwardness
- weakness in the arms, hands, legs, or feet
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Seek emergency medical attention or call 115
Further information
Copyright 2020 Truven Health Analytics, Inc. All Rights Reserved.
Medical Disclaimer
The content of Holevn is solely for the purpose of providing information about Thuốc Elotuzumab (Intravenous) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/cons/elotuzumab-intravenous.html
Other medical problems
The presence of other medical problems may affect the use of elotuzumab. Make sure you tell your doctor if you have any other medical problems, especially:
- Infection—May decrease your body’s ability to fight infections.
- Liver disease—Use with caution. May make this condition worse.
Proper use of elotuzumab
Medicines used to treat cancer are very strong and can have many side effects. Before receiving elotuzumab, make sure you understand all of the risks and benefits. It is important for you to work closely with your doctor during your treatment.
A nurse or other trained health professional will give you elotuzumab in a medical facility. It is given through a needle placed into one of your veins.
Your doctor will give you elotuzumab every week for 2 cycles (28 days each cycle) together with lenalidomide and dexamethasone or pomalidomide and dexamethasone. For cycles 3 and up, you will receive elotuzumab every 2 weeks together with lenalidomide and dexamethasone or every 4 weeks together with pomalidomide and dexamethasone.
Your doctor may give you other medicines (eg, allergy medicine, fever medicine, stomach medicine, or steroid) 45 to 90 minutes before infusion to prevent unwanted effects (eg, infusion reactions).
Elotuzumab should come with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Precautions while using elotuzumab
It is very important that your doctor check you at regular visits to make sure that elotuzumab is working properly. Blood tests may be needed to check for unwanted effects.
Using elotuzumab together with lenalidomide and dexamethasone or pomalidomide and dexamethasone while you are pregnant can harm your unborn baby. Men and women should use an effective form of birth control to prevent pregnancy during treatment with elotuzumab. If you think you have become pregnant while receiving the medicine, tell your doctor right away.
Infusion reactions may occur with elotuzumab. Tell your doctor right away if you have a skin rash, dizziness, fever or chills, headache, nausea or vomiting, slow or fast heartbeat, lightheadedness or fainting, sweating, or unusual tiredness or weakness.
Call your doctor right away if you have a cough that would not go away, weight loss, night sweats, fever, chills, or flu-like symptoms, such as a runny or stuffy nose, headache, or blurred vision. These may be symptoms of an infection.
Using elotuzumab may increase your risk of getting other types of cancer (including skin cancer). Talk to your doctor if you have concerns about this risk.
Check with your doctor right away if you have pain or tenderness in the upper stomach, pale stools, dark urine, loss of appetite, nausea, vomiting, or yellow eyes or skin. These could be symptoms of a serious liver problem.
Before you have any medical tests, tell the medical doctor in charge that you are receiving elotuzumab. The results of some tests may be affected by elotuzumab.
Elotuzumab side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur:
More common
- Blurred vision
- body aches or pain
- chest pain
- chills
- clay-colored stools
- confusion
- cough
- dark urine
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- ear congestion
- fever
- headache
- hives, itching, skin rash
- hoarseness
- irritation
- joint pain, stiffness, or swelling
- loss of appetite
- loss of voice
- lower back or side pain
- nasal congestion
- nausea
- nervousness
- painful or difficult urination
- persistent sore that does not heal
- pink skin growth
- pounding in the ears
- reddish patch or irritated area
- redness of the skin
- runny nose
- shiny skin bump
- slow or fast heartbeat
- sneezing
- sore throat
- stomach pain or tenderness
- stuffy nose
- sweating
- swelling of the eyelids, face, lips, hands, or feet
- tightness in the chest
- troubled breathing or swallowing
- unusual tiredness or weakness
- vomiting
- white, yellow or waxy scar-like area on the skin
- yellow eyes or skin
Less common
- Agitation
- anxiety
- decreased awareness or responsiveness
- decreased urine output
- depression
- dizziness or lightheadedness
- fainting
- fast heartbeat
- hostility
- irritability
- loss of consciousness
- muscle twitching
- pale skin
- rapid weight gain
- seizures
- severe sleepiness
- troubled breathing with exertion
- unusual bleeding or bruising
- unusual drowsiness, dullness, or feeling of sluggishness
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Blindness
- burning, numbness, tingling, or painful sensations
- decreased appetite
- decreased vision
- decreased weight
- diarrhea
- difficulty having a bowel movement
- muscle aches
- night sweats
- pain in the arms or legs
- unsteadiness or awkwardness
- weakness in the arms, hands, legs, or feet
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Seek emergency medical attention or call 115
Further information
Copyright 2020 Truven Health Analytics, Inc. All Rights Reserved.
Medical Disclaimer
The content of Holevn is solely for the purpose of providing information about Thuốc Elotuzumab (Intravenous) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/cons/elotuzumab-intravenous.html
