Thuốc Edoxaban

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Thuốc Edoxaban
Thuốc Edoxaban

Hovevn Health share articles about :Thuốc Edoxaban  , side effects – dosage , Thuốc Edoxaban what disease treatment.Other noted issues. Please refer to the details below.

Generic Name: edoxaban (e DOX a ban)
Brand Name:Savaysa

Medically reviewed by Holevn.org on Jun 27, 2018 – Written by Cerner Multum

What is edoxaban?

Edoxaban blocks the activity of certain clotting substances in the blood.

Edoxaban is used to lower the risk of stroke caused by a blood clot in people with a heart rhythm disorder called atrial fibrillation. edoxaban is used when the atrial fibrillation is not caused by a heart valve problem.

Edoxaban is also used to treat a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). A DVT can sometimes occur after a person has been treated with an injectable blood thinner for 5 to 10 days.

Edoxaban may also be used for purposes not listed in this medication guide.

Important Information

Edoxaban can cause you to bleed more easily. Call your doctor at once if you have signs of bleeding such as: bleeding gums, nosebleeds, heavy menstrual periods or abnormal vaginal bleeding, blood in your urine, bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Many other drugs can increase your risk of bleeding when used with edoxaban. Tell your doctor about all medicines you have recently used.

Edoxaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). Tell any doctor who treats you that you are taking edoxaban.

Do not stop taking edoxaban without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.

Before taking this medicine

You should not use edoxaban if you are allergic to it, or if you have active or uncontrolled bleeding.

Edoxaban can cause a very serious blood clot around your spinal cord if you undergo a spinal tap or receive spinal anesthesia (epidural). This type of blood clot could cause long-term paralysis, and may be more likely to occur if:

  • you have a genetic spinal defect;

  • you have a spinal catheter in place;

  • you have a history of spinal surgery or repeated spinal taps;

  • you have recently had a spinal tap or epidural anesthesia;

  • you are taking an NSAID–Advil, Aleve, Motrin, and others; or

  • you are using other medicines to treat or prevent blood clots.

Edoxaban may cause you to bleed more easily, especially if you have:

  • a bleeding disorder that is inherited or caused by disease;

  • hemorrhagic stroke;

  • uncontrolled high blood pressure;

  • stomach or intestinal bleeding or ulcer; or

  • if you take certain medicines such as aspirin, , heparin, warfarin (Coumadin, ), (Plavix), or certain antidepressants.

Tell your doctor if you have ever had:

  • an artificial heart valve;

  • bleeding problems; or

  • liver or kidney disease.

Taking edoxaban during pregnancy may cause bleeding in the mother or the unborn baby. Tell your doctor if you are pregnant or if you become pregnant.

You should not breast-feed while using edoxaban.

How should I take edoxaban?

Your kidney function may need to be checked before you start edoxaban.

Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take edoxaban with or without food.

If you cannot swallow a tablet whole, crush the tablet and mix it with 2 or 3 ounces of water or applesauce. Swallow the mixture right away without chewing. Do not save it for later use.

Edoxaban can make it easier for you to bleed, even from a minor injury. Seek medical attention if you have bleeding that will not stop.

If you need surgery, dental work, or a medical procedure, tell the doctor or dentist ahead of time that you are using this medication. If you need anesthesia, you may need to stop using edoxaban for a short time.

Do not change your dose or stop taking this medication without first talking to your doctor. Stopping suddenly can increase your risk of blood clot or stroke.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

Get your prescription refilled before you run out of medicine completely.

What happens if I overdose?

Seek emergency medical attention or call 115.

Overdose may cause excessive bleeding.

What should I avoid while taking edoxaban?

Avoid activities that may increase your risk of bleeding or injury. Use extra care to prevent bleeding while shaving or brushing your teeth.

Edoxaban side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Also seek emergency medical attention if you have symptoms of a spinal blood clot: back pain, numbness or muscle weakness in your lower body, or loss of bladder or bowel control.

Edoxaban can cause you to bleed more easily. Call your doctor at once if you have signs of bleeding such as:

  • easy bruising or bleeding (nosebleeds, bleeding gums, heavy menstrual bleeding);

  • pain, swelling, or drainage from a wound or where a needle was injected in your skin;

  • bleeding from wounds or needle injections, any bleeding that will not stop;

  • headaches, dizziness, weakness, feeling like you might pass out;

  • urine that looks red, pink, or brown; or

  • bloody or tarry stools, coughing up blood or vomit that looks like coffee grounds.

Common side effects may include:

  • bleeding; or

  • low red blood cells (anemia)–pale skin, unusual tiredness, feeling light-headed or short of breath, cold hands and feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Edoxaban dosing information

Usual Adult Dose for Atrial Fibrillation:

60 mg orally once a day

Use: Prevention of stroke and systemic embolism in nonvalvular atrial fibrillation

Usual Adult Dose for Deep Vein Thrombosis:

60 mg orally once a day following 5 to 10 days of initial therapy with a parenteral anticoagulant

Uses: Treatment of deep venous thrombosis and pulmonary embolism following 5-10 days of initial parenteral anticoagulant therapy

Usual Adult Dose for Pulmonary Embolism:

60 mg orally once a day following 5 to 10 days of initial therapy with a parenteral anticoagulant

Uses: Treatment of deep venous thrombosis and pulmonary embolism following 5-10 days of initial parenteral anticoagulant therapy

What other drugs will affect edoxaban?

Tell your doctor about all your other medicines, especially:

  • any other medications to treat or prevent blood clots;

  • a blood thinner–heparin warfarin (Coumadin, Jantoven);

  • NSAIDs (nonsteroidal anti-inflammatory drugs)–aspirin, (Advil, Motrin), (Aleve), celecoxib, diclofenac, , meloxicam, and others; or

  • an antidepressant–citalopram, duloxetine, fluoxetine, sertraline, paroxetine, venlafaxine, Cymbalta, , Pristiq, Paxil, Zoloft, and others.

This list is not complete and many other drugs may affect edoxaban. This includes prescription and over-the-counter medicines, vitamins, and . Not all possible drug interactions are listed here.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

The content of Holevn is solely for the purpose of providing information about Thuốc Edoxaban  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/mtm/edoxaban.html

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