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Generic Name: dimethyl fumarate (dye METH il FUE mar ate)
Brand Name:Tecfidera, Tecfidera Starter Pack
Medically reviewed by Holevn.org on Dec 16, 2019 – Written by Cerner Multum
What is dimethyl fumarate?
Dimethyl fumarate is used to treat relapsing multiple sclerosis.
Dimethyl fumarate may also be used for purposes not listed in this medication guide.
Dimethyl fumarate may cause a serious viral infection of the brain that can lead to disability or death. Call your doctor right away if you have any change in your mental state, decreased vision, weakness on one side of your body, or problems with speech or walking. These symptoms may start gradually and get worse quickly.
Before taking this medicine
You should not use dimethyl fumarate if you are allergic to it.
To make sure dimethyl fumarate is safe for you, tell your doctor if you have:
an active infection; or
low white blood cell (WBC) counts.
It is not known whether dimethyl fumarate will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using dimethyl fumarate.
If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of dimethyl fumarate on the baby.
It is not known whether dimethyl fumarate passes into breast milk or if it could harm a nursing baby. Tell your doctor if you are breast-feeding a baby.
How should I take dimethyl fumarate?
Your doctor will perform blood tests to make sure you do not have conditions that would prevent you from safely using dimethyl fumarate.
Follow all directions on your prescription label. Your doctor may occasionally change your dose. Do not take this medicine in larger or smaller amounts or for longer than recommended.
You may take dimethyl fumarate with or without food. Taking the medicine with food may help prevent flushing (warmth, itching, or burning sensations).
Do not crush, chew, break, or open a dimethyl fumarate capsule. Swallow it whole.
Dimethyl fumarate is usually given in two different strengths, one for a starter dose and the other for a maintenance dose. The starter dose is usually taken for only 7 days. Follow your doctor’s dosing instructions very carefully.
While using dimethyl fumarate, you will need frequent blood tests.
Store at room temperature away from moisture, heat, and light. Throw away any unused capsules 90 days after you first opened the bottle.
What happens if I miss a dose?
Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call 115.
What should I avoid while taking dimethyl fumarate?
Follow your doctor’s instructions about any restrictions on food, beverages, or activity.
Dimethyl fumarate side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Dimethyl fumarate may cause a serious viral infection of the brain that can lead to disability or death. Symptoms may start gradually and get worse quickly. Call your doctor right away if you have:
any change in your mental state;
weakness on one side of your body; or
problems with speech or walking.
Call your doctor at once if you have:
fever, pain when swallowing, cold or flu symptoms;
severe redness or feelings of warmth, tingling, itching, or burning; or
liver problems–loss of appetite, upper stomach pain (right side), tiredness, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).
Common side effects may include:
stomach pain, indigestion;
nausea, vomiting, diarrhea;
rash, itching; or
flushing (warmth, redness, or tingly feeling).
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Dimethyl fumarate dosing information
Usual Adult Dose for Multiple Sclerosis:
Initial dose: 120 mg orally twice a day for 7 days
Maintenance dose: 240 mg orally twice a day
Approved indication: The treatment of patients with relapsing-remitting multiple sclerosis.
What other drugs will affect dimethyl fumarate?
Other drugs may interact with dimethyl fumarate, including prescription and over-the-counter medicines, vitamins, and . Tell your doctor about all your current medicines and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 4.01.
The content of Holevn is solely for the purpose of providing information about Thuốc Dimethyl fumarate and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/mtm/dimethyl-fumarate.html
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