Thuốc Danshen

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Thuốc Danshen
Thuốc Danshen

Hovevn Health chia sẻ các bài viết về: Thuốc Danshen, tác dụng phụ – liều lượng, Thuốc Danshen điều trị bệnh gì. Các vấn đề lưu ý khác. Vui lòng tham khảo các chi tiết dưới đây.

Tên khoa học: Salvia miltiorrhiza Bunge
Tên thường gọi: Dan shen, Danshen, Radix, Tan-shen, Tanshen

Holevn.org xem xét y tế. Cập nhật lần cuối vào ngày 23 tháng 12 năm 2019.

Tổng quan lâm sàng

Sử dụng

Danshen đã được sử dụng rộng rãi trong y học cổ truyền Trung Quốc như một loại thảo mộc duy nhất và trong các công thức đa bào. Các nghiên cứu lâm sàng hạn chế đã cho thấy hiệu quả trong bệnh động mạch vành và đột quỵ thiếu máu cục bộ cấp tính, nhưng chất lượng phương pháp làm hạn chế tính hợp lệ và ngoại suy của những phát hiện này.

Liều dùng

Các thành phần hoạt động trong các chế phẩm thương mại có sẵn của danshen rất khác nhau. Liều bao gồm danshen 20 mg / kg viên nang. Liều dùng chiết xuất từ rễ danshen 5 g hai lần mỗi ngày trong 60 ngày đã được sử dụng ở bệnh nhân tiểu đường mắc bệnh tim mạch vành.

Chống chỉ định

Chống chỉ định chưa được xác định.

Mang thai / cho con bú

Tránh sử dụng. Thông tin liên quan đến an toàn và hiệu quả trong thai kỳ và cho con bú là thiếu.

Tương tác

Danshen có thể can thiệp vào nồng độ digoxin trong phòng thí nghiệm và làm tăng tác dụng chống đông máu của warfarin. Nó có thể làm giảm nồng độ trong huyết tương và do đó tác dụng dược lý của midazolam. Danshen ức chế nhiều enzyme cytochrom P450 (CYP-450) trong ống nghiệm.

Phản ứng trái ngược

Phản ứng có hại bao gồm dị ứng, chóng mặt, nhức đầu, triệu chứng GI nhẹ và giảm tiểu cầu có hồi phục.

Chất độc

Không có dữ liệu.

Gia đình khoa học

  • Lamiaceae (bạc hà)

Thực vật học

Danshen là một loại thảo mộc lâu năm được tìm thấy chủ yếu trên các sườn đồi đầy nắng và các cạnh suối ở Trung Quốc. Nó có hoa màu xanh tím nở vào mùa hè, với lá hình bầu dục, có răng cưa. Quả là một hạt màu nâu hình bầu dục. Rễ đỏ tươi rực rỡ của Danshen, từ đó nhiều tên phổ biến bắt nguồn, là phần dược liệu chính của cây. Danshen có liên quan đến cây xô thơm thông thường, thảo mộc ẩm thực.Wu 2007, Zhou 2005 Một nghiên cứu về các mẫu được bán ở thị trường Trung Quốc đã xác định 18 loài Salvia liên quan được thu thập, sử dụng và bán như danshen, và đánh giá cách sử dụng dân gian, chức năng truyền thống và hóa học. Li 2008 Mặc dù chỉ có S. miltiorrhiza được ghi nhận là loài danshen chính thức trong Dược điển của Cộng hòa Nhân dân Trung Hoa , Salvia przewalskii Maxim được sử dụng rộng rãi ở miền nam Trung Quốc. Sự đa dạng di truyền và cấu trúc quần thể của S. miltiorrhiza đã được nghiên cứu. Năm 2010 Danshen có liên quan đến các loài Salvia khác như Salvia hispanica L. (chia) và Salvia officinalis (cây xô thơm).

Lịch sử

Danshen được coi là một trong những loại thuốc truyền thống quan trọng nhất của Trung Quốc và được sử dụng rộng rãi ở các nước châu Á.Fang 2010 “Thuốc nhỏ giọt” được tạo ra bằng cách trộn nhiệt chiết xuất với tá dược và sau đó nhỏ giọt hỗn hợp vào một chất lỏng làm mát không tan cho đến khi hình thành các giọt rắn. .Zhou 2005 Là một chất bổ sung thảo dược duy nhất, S. miltiorrhiza đã được nghiên cứu trong các thử nghiệm lâm sàng về tác dụng của nó đối với các yếu tố nguy cơ tim mạch ở bệnh nhân tăng lipid máu, tăng huyết áp và tiểu đường.Qian 2012, Qian 2012, van Poppel 2015

Theo truyền thống, danshen đã được sử dụng để cải thiện chức năng cơ thể (ví dụ, thúc đẩy lưu thông, lưu lượng máu), cũng như để điều trị xuất huyết, đau bụng kinh, sẩy thai, sưng, mất ngủ và viêm gan. Các ứng dụng chính gần đây bao gồm điều trị các bệnh về tim mạch và mạch máu não.Wang 2007, Zhou 2005

Hóa học

Hơn 50 hợp chất đã được xác định trong danshen, phần lớn là diterpen lipophilic, được gọi là tanshinones, và các hợp chất phenolic phân cực.Wang 2007 Tác dụng kháng khuẩn, chống oxy hóa và chống ung thư được quy cho các hợp chất lipophilic, trong đó hơn 30 đã được mô tả; tanshinone I, tanshinone IIA và cryptotanshinone là thành phần chính. Các hợp chất hydrophilic từ danshen bao gồm các axit phenolic, bao gồm axit caffeic và các dẫn xuất của nó, chẳng hạn như danshensu, axit salvianolic A và B, axit rosmarinic và axit prolithospermic.Jiang 2005, Wang 2007 Các hợp chất khác bao gồm baicalin, beta-sitosterol, daucosterol, flavanones, vitamin E và tannin.Jiang 2005, Wang 2007, Zhou 2005

Một nghiên cứu về các biến thể hóa học của 13 thành phần trong 74 mẫu danshen được thu thập ở Trung Quốc đã được thực hiện bằng phân tích sắc ký lỏng hiệu năng cao (HPLC). Sự thay đổi theo mùa và trồng trọt ở danshen được trồng ở Úc cũng đã được phân tích. 2009, Sheng 2009 Một nghiên cứu cộng hưởng từ hạt nhân siêu kinh tế đã kiểm tra các chất chuyển hóa chính của 3 giống cây trồng khác biệt về kiểu hình của danshen.Dai 2010 Các quy trình phân tích để xác định các thành phần quan trọng trong danshen thô đã được phổ biến, với kỹ thuật quang phổ / khối diode / HPLC nổi bật nhất. 2011, Park 2008 Các phép đo hợp chất danshen trong dịch cơ thể đã đạt đượcLu 2008 và một số nghiên cứu về dược động học và phân phối đã được tiến hành trên các thành phần biệt lập và tương tác của chúng với nhau.Bi 2008, Chang 2010, Pan 2008, Xiaohui 2007

Công dụng và dược lý

Nghiện rượu

Dữ liệu động vật

Cryptotanshinone và chiết xuất danshen có tác dụng bảo vệ chống lại tổn thương ethanol đối với tế bào gan chuột.Yin 2009 Các nghiên cứu cho thấy tanshinone IIA có thể ức chế việc uống rượu tự nguyện ở chuột khi bị nghiện rượu gây ra. Cheng 2007, Xu 2005 2009, Xiping 2009 Nó cũng bảo vệ chống lại tổn thương tái thiếu máu cục bộ trong ghép gan thử nghiệm trên chuột .iang 2009 Trong một mô hình chuột, danshen đã được bảo vệ chống lại thiệt hại liên quan đến bệnh gan do rượu.

Tác dụng chống huyết khối

Dữ liệu động vật

Các hành động chống huyết khối của danshen đã được báo cáo trong các thí nghiệm trên động vật.Chang 1985, Dong 1996, Yu 1994, Zou 1993

Hoạt động chống dị ứng

Dữ liệu in vitro

Trong một nghiên cứu để xem xét ảnh hưởng của S. miltiorrhiza đối với sự tạo xương và sự biệt hóa nguyên bào xương, phần S. miltiorrhiza (phân lập metanol và ethanol) với nồng độ thấp của tanshinone IIA bị ức chế hủy xương.

Tác dụng chống oxy hóa

Dữ liệu lâm sàng

Tác dụng của chiết xuất rễ S. miltiorrhiza đối với dấu ấn sinh học của stress oxy hóa ở bệnh nhân tiểu đường mắc bệnh tim mạch vành đã được nghiên cứu trong một thử nghiệm ngẫu nhiên, có đối chứng giả dược (N = 62). Chỉ có nồng độ malonaldehyd huyết thanh giảm đáng kể sau 30 ngày điều trị (5 g hai lần mỗi ngày) so với đường cơ sở ( P <0,05), với mức giảm thêm sau 60 ngày ( P <0,005). Không có dấu ấn sinh học căng thẳng oxy hóa khác thay đổi đáng kể. Tương tự, không có thông số lipid nào bị ảnh hưởng bởi việc bổ sung chiết xuất từ rễ S. miltiorrhiza.Qian 2012

Ung thư

Dữ liệu in vitro

Danshen và các thành phần của nó ức chế sự phát triển của một số loại tế bào ung thư, bao gồm vú, tuyến tiền liệt Yang 2010, Gong 2011, gan 2010, Lee 2010 và đại tràng. Các tác dụng dường như chủ yếu là do tanshinone. Hiệu quả trong ung thư tế bào gan có thể được điều chỉnh thông qua tín hiệu TGF-beta / SMAD, Liu 2010 trong khi hiệu ứng trong các tế bào ung thư tuyến tiền liệt đã được quy cho con đường PI3-kinase / AKT. Các thí nghiệm năm 2010 cho thấy danshen ức chế sự hình thành mạch máu, có thể là do tiền điện tử. và tanoshinone IIa.Fan 2006

Dữ liệu động vật

Tanshinone Tôi đã được quan sát thấy để ức chế xenograft ung thư tuyến tiền liệt ở chuột.Gong 2011

Dữ liệu lâm sàng

Một phân tích đoàn hệ hồi cứu cho thấy thời gian sống sót tăng nhẹ ở bệnh nhân ung thư ruột kết sử dụng danshen với liều lượng lớn hơn và trong thời gian dài hơn.

Suy giảm nhận thức

Dữ liệu động vật

Trong một nghiên cứu trên chuột, crytotanshinone làm suy giảm lắng đọng beta-amyloid trong não, Mei 2009 và một nghiên cứu khác cho thấy ức chế cholinesterase, cho thấy tiềm năng sử dụng trong bệnh Alzheimer.

Bệnh động mạch vành

Dữ liệu in vitro

Trong một nghiên cứu, một chiết xuất tiêu chuẩn của các tế bào cơ tim chuột được bảo vệ bởi danshen khỏi yếu tố hoại tử khối u do apoptosis gây ra. Trong các nguyên bào sợi tim nuôi cấy, chiết xuất làm giảm tổng hợp collagen. 2009 Các tế bào RAW 264.7 được kích thích bằng lipopolysacarit, tiếp tục hỗ trợ các cơ chế chống viêm cho danshen.Jeon 2008 Tanshinone IIA ức chế sự di chuyển của các tế bào cơ trơn động mạch chủ của con người thông qua con đường AKT và ma trận metallicoprotease-9.Jin 2008

Dữ liệu động vật

Trong một nghiên cứu trên chuột, danshen là thuốc bảo vệ tim mạch cho kích thước và tỷ lệ tử vong của nhồi máu, và trong một thí nghiệm khác, danshen đã chứng minh tác dụng tương đương với captopril. . Sự xâm nhập của đại thực bào và yếu tố tăng trưởng biến đổi (TGF) Sự tiết rabeta cũng bị chặn.Ren 2010 Tác dụng của phenolic danshen thành phần danshensu trên con đường homocysteine đã được nghiên cứu trong một mô hình chuột, với mức độ tổng hợp huyết tương giảm trong 3 tuần. điều trị, có thể dẫn đến kích hoạt con đường transulfu hóa.Cao 2009

Dữ liệu lâm sàng

Một đánh giá về các thử nghiệm sử dụng danshen để điều trị đau thắt ngực báo cáo rằng nó có thể tốt hơn isosorbide dinitrate để quản lý đau thắt ngực lâu dài. Danshen dường như cũng có hiệu quả trong việc làm giảm đau thắt ngực do co thắt động mạch vành, có thể là do tính chất đối kháng canxi của nó. Chương 2007, Zhou 2005 Một thử nghiệm của danshen / Pueraria lobata đã tìm thấy những cải thiện khiêm tốn về các thông số tim mạch trong hơn 1 năm điều trị. tác dụng của chiết xuất rễ S. miltiorrhiza trên dấu ấn sinh học của bệnh tim mạch vành (CHD) (yếu tố von Willebrand [vWF] và phân tử kết dính tế bào mạch máu huyết thanh-1 [sVCAM-1]) đã được nghiên cứu trong một thử nghiệm ngẫu nhiên, có đối chứng giả dược (N = 62). Bệnh nhân đái tháo đường mắc CHD đã nhận được chiết xuất từ rễ S. miltiorrhiza (5 g hai lần mỗi ngày trong 60 ngày) đã giảm đáng kể sVCAM-1, vWF và cholesterol lipoprotein mật độ thấp oxy hóa (LDL) ( P <0,05, P <0,05, và P <0,01, tương ứng). Điều trị được dung nạp tốt mà không có tác dụng phụ nào được báo cáo.Qian 2012

Hiệu quả rõ rệt trong điều trị nhồi máu cơ tim (MI) có thể là do tác dụng an thần, chống oxy hóa và kháng tiểu cầu, cũng như cải thiện vi tuần hoàn mạch vành. Danshen cũng làm giảm chấn thương tái tưới máu cơ tim ở bệnh nhân nhồi máu cơ tim cấp tính sau can thiệp qua da.Cheng 2007

Bệnh tiểu đường

Dữ liệu in vitro

Tanshinone tăng cường hoạt động insulin trong các tế bào buồng trứng của chuột đồng Trung Quốc và trong tế bào mỡ. Năm 2009 Con đường qua đó dihydrotanshinone có thể ảnh hưởng đến glucose trong máu đã được kiểm tra trong các thí nghiệm tế bào.

Dữ liệu lâm sàng

Trong một thử nghiệm chéo ngẫu nhiên, mù đôi, có đối chứng giả dược ở bệnh nhân tăng lipid máu và tăng huyết áp (N = 20), một liều chiết xuất từ rễ S. miltiorrhiza 1 g 3 lần mỗi ngày trong 28 ngày không ảnh hưởng đến các thông số trao đổi chất. Những thay đổi về glucose huyết tương lúc đói, huyết sắc tố glycosyl hóa (HbA 1c ), insulin lúc đói, HOMA-IR và HOMA-B đã không được quan sát.van Poppel 2015

Viêm gan

Dữ liệu lâm sàng

Các nghiên cứu trước đây cho thấy danshen có thể hữu ích trong việc làm giảm buồn nôn, khó chịu, đau gan và trướng bụng ở bệnh nhân viêm gan mạn tính.Bai 1984, Chang 1985

Tăng lipid máu

Dữ liệu in vitro

Một hỗn hợp của danshen và P. lobata làm giảm tổng lượng cholesterol trong khi làm tăng biểu hiện phân tử kết dính nội bào (ICAM-1) và sự kết dính tế bào trong các đại thực bào của monocyte. . Một nghiên cứu proteomics chức năng của chiết xuất danshen trong các tế bào cơ trơn chuột tìm thấy tác dụng trên con đường căng thẳng oxy hóa. 2010

Dữ liệu động vật

ICAM-1 đã được xác nhận là mục tiêu tăng lipid máu của danshen trong mô hình chuột apolipoprotein E (- / -). Trong khi nồng độ lipid không bị thay đổi, sự gia tăng biểu hiện của ICAM-1 trong bạch cầu lưu hành được thúc đẩy bởi chế độ ăn kiêng xơ vữa đã được bãi bỏ bằng phương pháp điều trị danshen. Mảng xơ vữa động mạch cũng bị suy giảm trong thí nghiệm này. Năm 2008 Trong mô hình thỏ, triglyceride huyết thanh thấp hơn ở nhóm được cho ăn danshen so với nhóm đối chứng. Một mô hình chuột bị tăng lipid máu được điều trị bằng chiết xuất danshen cho thấy giảm tổng lượng cholesterol, LDL và triglyceride, với sự gia tăng của lipoprotein mật độ cao (HDL) .Ji 2008 Phân tích phân tử cho thấy một cơ chế hoạt động thông qua thụ thể X / thụ thể gan X. 2008

Dữ liệu lâm sàng

Một nghiên cứu ở những bệnh nhân cao tuổi mắc bệnh mỡ máu cao (N = 96) cho thấy giảm cholesterol toàn phần và LDL khi dùng danshen.Cheng 2007 Một nghiên cứu chéo, mù đôi, ngẫu nhiên có kiểm soát (N = 20) đã điều tra chiết xuất từ rễ S. miltiorrhiza được thực hiện là 1 g 3 lần hàng ngày trong 28 ngày ở những bệnh nhân có yếu tố nguy cơ mắc bệnh tim mạch (nghĩa là tăng lipid máu, tăng huyết áp). Sau khi sửa chữa các giá trị cơ bản và những thay đổi được quan sát bằng giả dược, chiết xuất từ rễ danshen đã gây ra sự gia tăng đáng kể về cholesterol LDL so với đường cơ sở và giả dược ( P <0,01 mỗi loại). Không có thông số lipid hoặc huyết áp, phản ứng mạch máu, chuyển hóa, chống oxy hóa, viêm hoặc đông máu thay đổi đáng kể. Liệt dây thần kinh mặt ngoại biên là một trong những tác dụng phụ nghiêm trọng xảy ra trong quá trình điều trị danshen.van Poppel 2015

Tăng huyết áp

Dữ liệu in vitro

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

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J Clin Pharmacol
. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix
Salviae miltiorrhizae
(danshen) [in Chinese].
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. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin
. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of
Salvia miltiorrhiza
(danshen) collected from different locations in China.
J Agric Food Chem
. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use.
J Clin Pharmacol
. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix
Salviae miltiorrhizae
(danshen) [in Chinese].
Yao Xue Xue Bao
. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin
. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza
(danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

Acta Pharmacol Sin. 2010;31(4):421-428.20228827Zhong GX, Li P, Zeng LJ, Guan J, Li DQ, Li SP. Chemical characteristics of Salvia miltiorrhiza (danshen) collected from different locations in China. J Agric Food Chem. 2009;57(15):6879-6887.19601629Zhou L, Zuo Z, Chow MS. Danshen: an overview of its chemistry, pharmacology, pharmacokinetics, and clinical use. J Clin Pharmacol. 2005;45(12):1345-1359.16291709Zou ZW, Xu LN, Tian JY. Antithrombotic and antiplatelet effects of rosmarinic acid, a water-soluble component isolated from radix Salviae miltiorrhizae (danshen) [in Chinese]. Yao Xue Xue Bao. 1993;28(4):241-245.8213164

Disclaimer

This information relates to an herbal, vitamin, mineral or other dietary supplement. This product has not been reviewed by the FDA to determine whether it is safe or effective and is not subject to the quality standards and safety information collection standards that are applicable to most prescription drugs. This information should not be used to decide whether or not to take this product. This information does not endorse this product as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this product. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this product. This information is not specific medical advice and does not replace information you receive from your health care provider. You should talk with your health care provider for complete information about the risks and benefits of using this product.

This product may adversely interact with certain health and medical conditions, other prescription and over-the-counter drugs, foods, or other dietary supplements. This product may be unsafe when used before surgery or other medical procedures. It is important to fully inform your doctor about the herbal, vitamins, mineral or any other supplements you are taking before any kind of surgery or medical procedure. With the exception of certain products that are generally recognized as safe in normal quantities, including use of folic acid and prenatal vitamins during pregnancy, this product has not been sufficiently studied to determine whether it is safe to use during pregnancy or nursing or by persons younger than 2 years of age.

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Danshen  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/npp/danshen.html

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