Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
-
new or worsening breathing problems (chest pain, wheezing, cough, feeling short of breath);
-
fever;
-
severe or ongoing diarrhea;
-
swelling, redness, or infection under or around your fingernails or toenails; or
-
a severe skin reaction–dry skin, redness, rash, acne, itching, peeling or blistering.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
-
diarrhea, loss of appetite;
-
weight loss;
-
rash, itching, dry skin;
-
eye redness, dryness, or itching;
-
hair loss;
-
problems with your nails;
-
mouth sores, mouth pain; or
-
cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Dacomitinib dosing information
Usual Adult Dose for Non-Small Cell Lung Cancer:
45 mg orally once a day until disease progression or unacceptable toxicity
Use: For the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test
What other drugs will affect dacomitinib?
Some medicines can make dacomitinib much less effective when taken at the same time. If you take any of the following medicines, take your dacomitinib dose 6 hours before or 10 hours after you take the other medicine:
-
an antacid; or
-
a stomach acid reducer (such as , Pepcid, Zantac).
Other drugs may affect dacomitinib, including prescription and over-the-counter medicines, vitamins, and . Tell your doctor about all your current medicines and any medicine you start or stop using.
Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 1.01.
Related questions
The content of Holevn is solely for the purpose of providing information about Thuốc Dacomitinib and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/mtm/dacomitinib.html
Drink plenty of liquids while you are taking dacomitinib.
Dacomitinib can cause severe diarrhea, which can be life-threatening if it leads to dehydration or infection.
If you have diarrhea while taking dacomitinib: Call your doctor right away. You may need to start taking anti-diarrhea medicine such as (Imodium) to quickly treat diarrhea.
Store at room temperature away from moisture and heat.
What happens if I miss a dose?
Skip the missed dose and use your next dose at the regular time. Do not take two doses at one time.
What happens if I overdose?
Seek emergency medical attention or call 115.
What should I avoid while taking dacomitinib?
Dacomitinib can cause skin reactions. Use a skin moisturizer and avoid sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.
Dacomitinib side effects
Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
-
new or worsening breathing problems (chest pain, wheezing, cough, feeling short of breath);
-
fever;
-
severe or ongoing diarrhea;
-
swelling, redness, or infection under or around your fingernails or toenails; or
-
a severe skin reaction–dry skin, redness, rash, acne, itching, peeling or blistering.
Your cancer treatments may be delayed or permanently discontinued if you have certain side effects.
Common side effects may include:
-
diarrhea, loss of appetite;
-
weight loss;
-
rash, itching, dry skin;
-
eye redness, dryness, or itching;
-
hair loss;
-
problems with your nails;
-
mouth sores, mouth pain; or
-
cold symptoms such as stuffy nose, sneezing, sore throat.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
Dacomitinib dosing information
Usual Adult Dose for Non-Small Cell Lung Cancer:
45 mg orally once a day until disease progression or unacceptable toxicity
Use: For the first-line treatment of patients with metastatic non-small cell lung cancer (NSCLC) with epidermal growth factor receptor (EGFR) exon 19 deletion or exon 21 L858R substitution mutations as detected by an FDA-approved test
What other drugs will affect dacomitinib?
Some medicines can make dacomitinib much less effective when taken at the same time. If you take any of the following medicines, take your dacomitinib dose 6 hours before or 10 hours after you take the other medicine:
-
an antacid; or
-
a stomach acid reducer (such as , Pepcid, Zantac).
Other drugs may affect dacomitinib, including prescription and over-the-counter medicines, vitamins, and . Tell your doctor about all your current medicines and any medicine you start or stop using.
Further information
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 1.01.
Related questions
The content of Holevn is solely for the purpose of providing information about Thuốc Dacomitinib and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/mtm/dacomitinib.html
