Adalimumab-adbm injection will lower the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
This medicine may cause other unwanted effects that may not occur until months or years after this medicine is used. A small number of people (including children and teenagers) who have used this type of medicine have developed certain types of cancer (eg, leukemia). Some patients also developed a rare type of cancer called lymphoma. Talk with your doctor if you or your child have unusual bleeding, bruising, or weakness, swollen lymph nodes in the neck, underarms, or groin, or unexplained weight loss. Also, check with your doctor right away if your skin has red, scaly patches, or raised bumps that are filled with pus.
Adalimumab-adbm injection may cause serious allergic reactions, including anaphylaxis. This can be life-threatening and requires immediate medical attention. Check with your doctor right away if you or your child have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.
Check with your doctor right away if you or your child have more than one of these symptoms: shortness of breath, swelling of the face, fingers, feet, or lower legs, or sudden weight gain. These may be signs of a heart condition called congestive heart failure (CHF).
Some people who have used this medicine developed lupus-like symptoms during treatment and got better after the medicine was stopped. Check with your doctor right away if you or your child start having chest pains, shortness of breath, joint pain, or a rash on your cheeks or arms that is sensitive to the sun.
Do not have any live vaccines (immunizations) while you or your child are being treated with adalimumab-adbm. Your child’s vaccines need to be current before he or she begins using this medicine. Be sure to ask your child’s doctor if you have any questions about this.
Cyltezo side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
- Bladder pain
- bloody or cloudy urine
- body aches or pain
- chills
- cough
- difficult, burning, or painful urination
- difficulty in breathing
- ear congestion
- fever
- frequent urge to urinate
- headache
- loss of voice
- lower back or side pain
- nasal congestion
- runny nose
- sneezing
- sore throat
- unusual tiredness or weakness
Less common
- Abnormal healing
- anxiety
- black, tarry stools
- bloating or swelling of the face, arms, hands, lower legs, or feet
- blue or pale skin
- blurred vision
- chest pain, possibly moving to the left arm, neck, or shoulder
- dark urine
- decreased vision
- diarrhea
- dizziness
- fainting
- fast, pounding, or irregular heartbeat or pulse
- fever with or without chills
- general feeling of tiredness or weakness
- hoarseness
- indigestion
- itching
- light-colored stools
- loss of appetite
- loss of strength or energy
- muscle pain or weakness
- nausea
- pain in the throat, arms, legs, or pelvis
- pain or discomfort in the arms, jaw, back, or neck
- painful or difficult urination
- rapid weight gain
- rash
- severe nausea or vomiting
- sores, ulcers, or white spots on the lips or in the mouth
- stomach pain
- sweating
- tingling of the hands or feet
- unpleasant breath odor
- unusual bleeding or bruising
- unusual weight gain or loss
- vomiting
- vomiting of blood
- weakness
- yellow eyes or skin
Incidence not known
- Blistering, peeling, or loosening of the skin
- constipation
- darkened urine
- indigestion
- itching joint or muscle pain
- pains in the stomach, side, or abdomen, possibly radiating to the back
- red, irritated eyes
- red skin lesions, often with a purple center
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Back pain
- bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
Incidence not known
- Hair loss, thinning of hair
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Seek emergency medical attention or call 115
Further information
Copyright 2020 Truven Health Analytics, Inc. All Rights Reserved.
Related questions
Medical Disclaimer
The content of Holevn is solely for the purpose of providing information about Thuốc Cyltezo (Subcutaneous) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/cons/cyltezo-subcutaneous.html
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Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
- Blood problems (eg, aplastic anemia, pancytopenia, thrombocytopenia), history of or
- Congestive heart failure or
- Guillain-Barré syndrome, history of or
- Infections (fungal, bacterial), history of or
- Leukopenia (low number of white blood cells) or
- Multiple sclerosis or
- Optic neuritis (eye problem) or
- Psoriasis (skin disease)—Use with caution. May make these conditions worse.
- Cancer, active or history of or
- Chronic obstructive pulmonary disease (COPD) or
- Granulomatosis polyangiitis—Use with caution. May increase the chance of getting new cancers.
- Diabetes or
- Hepatitis B, history of or
- Opportunistic infections, history of or
- Tuberculosis, history of—May increase chance for side effects.
- Infection, active—Should not be used in patients with this condition.
- Tuberculosis, active—Should be treated first before receiving this medicine.
Proper use of Cyltezo
This medicine is given as a shot under your skin in the upper thighs or stomach. It may sometimes be given at home to patients who do not need to be in the hospital or clinic. If you are using this medicine at home, your doctor or nurse will teach you how to prepare and inject the medicine. Be sure that you understand how to use this medicine.
This medicine comes with a Medication Guide and patient instructions. Read and follow these instructions carefully. Ask your doctor if you have any questions.
If you use this medicine at home, you will be shown the body areas where this shot can be given. Use a different body area each time you give yourself or your child a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems.
To use the prefilled syringe:
- Wash your hands with soap and water before and after using this medicine.
- Allow 15 to 30 minutes for the syringe to warm up to room temperature.
- Do not remove the needle cover on the prefilled syringe while allowing the medicine to reach to room temperature. Remove it before use.
- Check the liquid in the syringe. It should be clear and colorless to slightly yellow. Do not use the syringe if it is cloudy, discolored, or has particles in it.
- Do not inject into skin areas that are red, bruised, tender, hard, or scarred.
Dosing
The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For injection dosage forms (prefilled syringe):
- For Crohn’s disease:
- Adults—At first (Day 1), 160 milligrams (mg) injected under the skin (four 40 mg injections in one day or two 40 mg injections a day for two days). Then 2 weeks later (Day 15), a dose of 80 mg is given. A maintenance dose of 40 mg is given at week 4 (Day 29) and every other week thereafter.
- Children—Use and dose must be determined by your doctor.
- For juvenile idiopathic arthritis:
- Children 4 years of age and older weighing 30 kilograms (kg) or more—40 milligrams (mg) injected under the skin every other week.
- Children younger than 4 years of age weighing less than 30 kg—Use and dose must be determined by your doctor.
- For plaque psoriasis:
- Adults—At first, 80 milligrams (mg) injected under the skin, then 40 mg 1 week after the initial dose and every other week thereafter.
- Children—Use and dose must be determined by your doctor.
- For rheumatoid arthritis, psoriatic arthritis, or ankylosing spondylitis:
- Adults—40 milligrams (mg) injected under the skin every other week. Your doctor may adjust your dose if needed.
- Children—Use and dose must be determined by your doctor.
- For ulcerative colitis:
- Adults—At first (Day 1), 160 milligrams (mg) injected under the skin (four 40 mg injections in one day or two 40 mg injections a day for two days). Then 2 weeks later (Day 15), a dose of 80 mg is given. A maintenance dose of 40 mg is given at week 4 (Day 29) and every other week thereafter.
- Children—Use and dose must be determined by your doctor.
- For Crohn’s disease:
Missed dose
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Store in the refrigerator. Do not freeze.
Keep it in its original container. Protect from light. You may also store this medicine at room temperature for up to 14 days. Throw away any unused medicine after 14 days.
Throw away used syringes or pens in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.
Precautions while using Cyltezo
It is very important that your doctor check the progress of you or your child at regular visits to make sure this medicine is working properly. Blood tests may be needed to check for unwanted effects.
You or your child will need to have a skin test for tuberculosis before you start using this medicine. Tell your doctor if you or anyone in your home has ever had a positive reaction to a tuberculosis skin test.
Adalimumab-adbm injection will lower the number of some types of blood cells in your body. Because of this, you may bleed or get infections more easily. To help with these problems, avoid being near people who are sick or have infections. Wash your hands often. Stay away from rough sports or other situations where you could be bruised, cut, or injured. Brush and floss your teeth gently. Be careful when using sharp objects, including razors and fingernail clippers.
This medicine may cause other unwanted effects that may not occur until months or years after this medicine is used. A small number of people (including children and teenagers) who have used this type of medicine have developed certain types of cancer (eg, leukemia). Some patients also developed a rare type of cancer called lymphoma. Talk with your doctor if you or your child have unusual bleeding, bruising, or weakness, swollen lymph nodes in the neck, underarms, or groin, or unexplained weight loss. Also, check with your doctor right away if your skin has red, scaly patches, or raised bumps that are filled with pus.
Adalimumab-adbm injection may cause serious allergic reactions, including anaphylaxis. This can be life-threatening and requires immediate medical attention. Check with your doctor right away if you or your child have a rash, itching, hoarseness, trouble breathing, trouble swallowing, or any swelling of your hands, face, or mouth after using this medicine.
Check with your doctor right away if you or your child have more than one of these symptoms: shortness of breath, swelling of the face, fingers, feet, or lower legs, or sudden weight gain. These may be signs of a heart condition called congestive heart failure (CHF).
Some people who have used this medicine developed lupus-like symptoms during treatment and got better after the medicine was stopped. Check with your doctor right away if you or your child start having chest pains, shortness of breath, joint pain, or a rash on your cheeks or arms that is sensitive to the sun.
Do not have any live vaccines (immunizations) while you or your child are being treated with adalimumab-adbm. Your child’s vaccines need to be current before he or she begins using this medicine. Be sure to ask your child’s doctor if you have any questions about this.
Cyltezo side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
More common
- Bladder pain
- bloody or cloudy urine
- body aches or pain
- chills
- cough
- difficult, burning, or painful urination
- difficulty in breathing
- ear congestion
- fever
- frequent urge to urinate
- headache
- loss of voice
- lower back or side pain
- nasal congestion
- runny nose
- sneezing
- sore throat
- unusual tiredness or weakness
Less common
- Abnormal healing
- anxiety
- black, tarry stools
- bloating or swelling of the face, arms, hands, lower legs, or feet
- blue or pale skin
- blurred vision
- chest pain, possibly moving to the left arm, neck, or shoulder
- dark urine
- decreased vision
- diarrhea
- dizziness
- fainting
- fast, pounding, or irregular heartbeat or pulse
- fever with or without chills
- general feeling of tiredness or weakness
- hoarseness
- indigestion
- itching
- light-colored stools
- loss of appetite
- loss of strength or energy
- muscle pain or weakness
- nausea
- pain in the throat, arms, legs, or pelvis
- pain or discomfort in the arms, jaw, back, or neck
- painful or difficult urination
- rapid weight gain
- rash
- severe nausea or vomiting
- sores, ulcers, or white spots on the lips or in the mouth
- stomach pain
- sweating
- tingling of the hands or feet
- unpleasant breath odor
- unusual bleeding or bruising
- unusual weight gain or loss
- vomiting
- vomiting of blood
- weakness
- yellow eyes or skin
Incidence not known
- Blistering, peeling, or loosening of the skin
- constipation
- darkened urine
- indigestion
- itching joint or muscle pain
- pains in the stomach, side, or abdomen, possibly radiating to the back
- red, irritated eyes
- red skin lesions, often with a purple center
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
- Back pain
- bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
Incidence not known
- Hair loss, thinning of hair
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Seek emergency medical attention or call 115
Further information
Copyright 2020 Truven Health Analytics, Inc. All Rights Reserved.
Related questions
Medical Disclaimer
The content of Holevn is solely for the purpose of providing information about Thuốc Cyltezo (Subcutaneous) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/cons/cyltezo-subcutaneous.html
