Thuốc Corticotropin (Injection)

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Thuốc Corticotropin (Injection)
Thuốc Corticotropin (Injection)

Hovevn Health chia sẻ các bài viết về: Thuốc Corticotropin (Tiêm), tác dụng phụ – liều lượng, Thuốc Corticotropin (Tiêm) điều trị bệnh gì. Các vấn đề lưu ý khác. Vui lòng tham khảo các chi tiết dưới đây.

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Lớp dược lý: Corticotropin

Holevn.org xem xét y tế. Cập nhật lần cuối vào ngày 8 tháng 8 năm 2019.

Sử dụng cho corticotropin

Tiêm corticotropin lưu trữ được sử dụng để điều trị co thắt ở trẻ sơ sinh (co giật) ở trẻ sơ sinh và trẻ nhỏ dưới 2 tuổi. Nó cũng được sử dụng để điều trị người lớn với các dạng tái phát của bệnh đa xơ cứng. Corticotropin sẽ không chữa khỏi MS, nhưng nó có thể làm chậm một số tác dụng vô hiệu hóa và làm giảm số lần bùng phát (tái phát) của bệnh.

Tiêm corticotropin lưu trữ cũng được sử dụng để điều trị các rối loạn khớp (ví dụ viêm khớp vẩy nến, viêm khớp dạng thấp, viêm cột sống dính khớp), các bệnh tự miễn (ví dụ, bệnh lupus ban đỏ hệ thống hoặc SLE, viêm đa cơ), và một số bệnh. Hội chứng -Johnson), mắt (ví dụ, viêm giác mạc, viêm màng bồ đào sau lan tỏa và viêm màng đệm, viêm dây thần kinh thị giác) và phổi (ví dụ, bệnh sarcoidosis). Nó cũng được sử dụng để điều trị một số dị ứng (ví dụ, bệnh huyết thanh) và sưng (phù) của cơ thể.

Corticotropin chỉ có sẵn với toa thuốc của bác sĩ.

Trước khi sử dụng corticotropin

Khi quyết định sử dụng thuốc, rủi ro của việc dùng thuốc phải được cân nhắc với lợi ích mà nó sẽ làm. Đây là một quyết định mà bạn và bác sĩ của bạn sẽ đưa ra. Đối với corticotropin, cần xem xét những điều sau đây:

Dị ứng

  • Backache
  • blurred vision
  • body aches or pain
  • chest pain
  • chills
  • cough
  • difficulty with breathing
  • dizziness
  • ear congestion
  • earache
  • facial hair growth in females
  • fever
  • fractures
  • full or round face, neck, or trunk
  • headache
  • increased thirst or urination
  • irritability
  • loss of sexual desire or ability
  • loss of voice
  • menstrual irregularities
  • muscle wasting
  • nasal congestion
  • nervousness
  • pounding in the ears
  • redness or swelling in the ear
  • runny nose
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • tightness in the chest
  • unusual tiredness or weakness
  • white patches in the mouth or throat or on the tongue
  • white patches with diaper rash

Less common

  • Seizures

Incidence not known

  • Accumulation of pus
  • bruising
  • bulging soft spot on the head of an infant
  • change in the ability to see colors, especially blue or yellow
  • cold, clammy skin
  • confusion
  • decreased range of motion
  • decreased urine output
  • dilated neck veins
  • extreme tiredness or weakness
  • eyeballs bulge out of the eye sockets
  • fast, weak pulse
  • full or bloated feeling
  • heartburn
  • irregular breathing
  • irregular heartbeat
  • joint pain
  • large, flat, blue, or purplish patches in the skin
  • lightheadedness
  • limp
  • loss of appetite
  • nausea
  • pressure in the stomach
  • severe headache
  • slow healing
  • small red or purple spots on the skin
  • sweating
  • swelling of the abdominal or stomach area
  • swelling of the face, fingers, feet, or lower legs
  • swollen, red, or tender area of infection
  • trouble sleeping
  • vomiting
  • weight gain

Incidence not known-For adults only

  • Bloating
  • confusion
  • constipation
  • coughing up blood
  • dark urine
  • headache, sudden and severe
  • increased sweating
  • indigestion
  • loss of appetite
  • pain in the muscles
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • redness of the face
  • skin rash
  • unusual weight loss
  • weakness
  • yellow eyes or skin

Incidence not known-For infants only

  • Diarrhea
  • dry mouth
  • excess air or gas in the stomach or bowels
  • mood changes
  • muscle pain or cramps
  • numbness or tingling in the hands, feet, or lips
  • passing gas
  • problems with speech or speaking
  • swelling of the abdominal or stomach area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Blemishes on the skin
  • diarrhea
  • pimples

Less common

  • Changes in appetite

Incidence not known

  • Increased hair growth, especially on the face
  • muscle weakness

Incidence not known-For adults only

  • Feeling of constant movement of self or surroundings
  • sensation of spinning
  • thinning of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Corticotropin (Injection)  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/corticotropin-injection.html

Proper use of corticotropin

A nurse or other trained health professional will give you or your child corticotropin in a medical facility. It is given as a shot under your skin or into one of your muscles.

Repository corticotropin injection may sometimes be given at home to patients who do not need to be in the hospital. If you are using corticotropin at home, your or your child’s doctor will teach you how to prepare and inject the medicine. Be sure that you understand exactly how the medicine is prepared and injected.

If your child is receiving repository corticotropin injection to treat infantile spasms, corticotropin usually comes with a Medication Guide. It is very important that you read and follow the instructions carefully. Be sure to ask your child’s doctor about anything you do not understand.

You will be shown the body areas where this shot can be given. Use a different body area each time you give yourself a shot. Keep track of where you give each shot to make sure you rotate body areas. This will help prevent skin problems from the injections.

To use:

  • Take the vial from the refrigerator and let it warm to room temperature before using it. Do not over-pressurize the vial before withdrawing the medicine.
  • Wash your hands before and after using corticotropin.
  • Wipe the injection site with a new sterile alcohol wipe and let it dry before giving an injection.
  • Clean the top of the rubber stopper vial with a new sterile alcohol wipe.
  • Use a new needle or syringe to get the prescribed amount of medicine to be injected.
  • Give the medicine the way your doctor has instructed you.
  • Return the vial to the refrigerator after using it.

Dosing

The dose of corticotropin will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of corticotropin. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For injection dosage form (gel):
    • For infantile spasms:
      • Children 2 years of age and older—Use and dose must be determined by your doctor.
      • Infants and children younger than 2 years of age—Dose is based on body size and must be determined by your child’s doctor. The dose is usually 150 units per square meter (U/m2) of body size divided into two equal doses injected into a muscle per day for 2 weeks. Your child’s doctor will adjust the dose as needed.
    • For multiple sclerosis:
      • Adults—The dose is usually 80 to 120 units injected under your skin or into a muscle per day for 2 to 3 weeks. Your doctor will adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.
    • For other indications (joint disorders, autoimmune diseases, allergies, swelling, and certain conditions of the skin, eyes, and lungs):
      • Adults—The dose is usually 40 to 80 units injected under your skin or into a muscle every 24 to 72 hours. Your doctor will adjust your dose as needed.
      • Children—Use and dose must be determined by your doctor.

Missed dose

Corticotropin needs to be given on a fixed schedule. If you miss a dose or forget to use your medicine, call your doctor or pharmacist for instructions.

Storage

Store in the refrigerator. Do not freeze.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Throw away used needles in a hard, closed container that the needles cannot poke through. Keep this container away from children and pets.

Precautions while using corticotropin

It is very important that your doctor check your or your child’s progress at regular visits to make sure that corticotropin is working properly. Blood tests may be needed to check for any unwanted effects.

Do not receive live vaccines while you or your child are using corticotropin.

Using corticotropin while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using the medicine, tell your doctor right away.

Corticotropin may increase your risk of developing infections. Avoid being near people who are sick or have infections while you are using corticotropin. Check with your doctor immediately if you think you are getting an infection or if you get a fever or chills, cough or hoarseness, lower back or side pain, or painful or difficult urination.

Using too much of corticotropin or using it for a long time may increase your risk of having adrenal gland problems (eg, Cushing’s syndrome). The risk is greater for children and patients who use large amounts for a long time. Talk to your doctor right away if you or your child have more than one of these symptoms while you are using corticotropin: blurred vision, dizziness or fainting, a fast, irregular, or pounding heartbeat, fractures, increased thirst or urination, irritability, round or “moon” face, neck, or trunk, stomach pain, thin skin or easy bruising, weight gain or loss, or unusual tiredness or weakness.

Corticotropin may cause fluid retention (edema) in some patients. Carefully follow your doctor’s instructions about any special diet (especially on salt intake).

Corticotropin may mask or hide symptoms of other diseases while you are using it. Check with your doctor if you or your child have symptoms of infection, black, tarry stools, changes in body weight, difficulty with breathing, fast heart rate, increased thirst, stomach pain, unusual tiredness, or vomiting.

Check with your doctor right away if you start having severe abdominal or stomach burning, cramps, or pains, bloody or black, tarry stools, constipation or diarrhea, heartburn, indigestion, nausea, or vomiting of material that looks like coffee grounds. These could be symptoms of a serious stomach or bowel problem.

Corticotropin may cause changes in mood and behavior. Check with your doctor if you or your child have trouble sleeping, feeling depressed or irritable, mood swings, or other changes in behavior.

Check with your doctor right away if you or your child have any changes to your eyes, such as redness, itching, swelling, or vision changes while you are using corticotropin. Your doctor may want your eyes to be checked by an eye doctor (ophthalmologist).

Corticotropin may decrease bone mineral density when used for a long time. A low bone mineral density can cause slow growth and may lead to osteoporosis at any age. If you have any questions about this ask your doctor.

Do not stop using corticotropin suddenly without checking first with your doctor. Your doctor may want you or your child to gradually reduce the amount you are using before stopping it completely.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

Corticotropin side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

More common

  • Backache
  • blurred vision
  • body aches or pain
  • chest pain
  • chills
  • cough
  • difficulty with breathing
  • dizziness
  • ear congestion
  • earache
  • facial hair growth in females
  • fever
  • fractures
  • full or round face, neck, or trunk
  • headache
  • increased thirst or urination
  • irritability
  • loss of sexual desire or ability
  • loss of voice
  • menstrual irregularities
  • muscle wasting
  • nasal congestion
  • nervousness
  • pounding in the ears
  • redness or swelling in the ear
  • runny nose
  • slow or fast heartbeat
  • sneezing
  • sore throat
  • tightness in the chest
  • unusual tiredness or weakness
  • white patches in the mouth or throat or on the tongue
  • white patches with diaper rash

Less common

  • Seizures

Incidence not known

  • Accumulation of pus
  • bruising
  • bulging soft spot on the head of an infant
  • change in the ability to see colors, especially blue or yellow
  • cold, clammy skin
  • confusion
  • decreased range of motion
  • decreased urine output
  • dilated neck veins
  • extreme tiredness or weakness
  • eyeballs bulge out of the eye sockets
  • fast, weak pulse
  • full or bloated feeling
  • heartburn
  • irregular breathing
  • irregular heartbeat
  • joint pain
  • large, flat, blue, or purplish patches in the skin
  • lightheadedness
  • limp
  • loss of appetite
  • nausea
  • pressure in the stomach
  • severe headache
  • slow healing
  • small red or purple spots on the skin
  • sweating
  • swelling of the abdominal or stomach area
  • swelling of the face, fingers, feet, or lower legs
  • swollen, red, or tender area of infection
  • trouble sleeping
  • vomiting
  • weight gain

Incidence not known-For adults only

  • Bloating
  • confusion
  • constipation
  • coughing up blood
  • dark urine
  • headache, sudden and severe
  • increased sweating
  • indigestion
  • loss of appetite
  • pain in the muscles
  • pains in the stomach, side, or abdomen, possibly radiating to the back
  • redness of the face
  • skin rash
  • unusual weight loss
  • weakness
  • yellow eyes or skin

Incidence not known-For infants only

  • Diarrhea
  • dry mouth
  • excess air or gas in the stomach or bowels
  • mood changes
  • muscle pain or cramps
  • numbness or tingling in the hands, feet, or lips
  • passing gas
  • problems with speech or speaking
  • swelling of the abdominal or stomach area

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Blemishes on the skin
  • diarrhea
  • pimples

Less common

  • Changes in appetite

Incidence not known

  • Increased hair growth, especially on the face
  • muscle weakness

Incidence not known-For adults only

  • Feeling of constant movement of self or surroundings
  • sensation of spinning
  • thinning of the skin

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc Corticotropin (Injection)  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/corticotropin-injection.html

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