Thuốc CodiClear DH (Oral)

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Thuốc CodiClear DH (Oral)
Thuốc CodiClear DH (Oral)

Hovevn Health chia sẻ các bài viết về: Thuốc CodiClear DH (Thuốc uống), tác dụng phụ – liều lượng, Thuốc CodiClear DH (Thuốc uống) điều trị bệnh gì. Các vấn đề lưu ý khác. Vui lòng tham khảo các chi tiết dưới đây.

Tên chung: (Đường uống)

gwye-FEN-e-sin, hye-droe-KOE-by by-TAR-trate

Đường uống (Giải pháp)

Cảnh báo: Nghiện, Lạm dụng và Lạm dụng; Suy hô hấp đe dọa tính mạng, nuốt phải tai nạn, lỗi dùng thuốc; Tương tác Cytochrom P450 3A4; Sử dụng đồng thời với thuốc Benzodiazepin hoặc thuốc ức chế thần kinh trung ương khác; Tương tác với rượu; Hội chứng rút opioid sơ sinhHydrocodone bitartrate / guaifenesin khiến người dùng có nguy cơ nghiện, lạm dụng và lạm dụng, có thể dẫn đến quá liều và tử vong. Đánh giá nguy cơ của bệnh nhân trước khi kê đơn và theo dõi chặt chẽ các hành vi và tình trạng này. Có thể xảy ra trầm cảm, đe dọa tính mạng hoặc suy hô hấp gây tử vong. Theo dõi chặt chẽ, đặc biệt là khi bắt đầu hoặc khi được sử dụng ở những bệnh nhân có nguy cơ cao hơn. Việc uống hydrocodone bitartrate / guaifenesin, đặc biệt là ở trẻ em, có thể dẫn đến việc sử dụng hydrocodone một cách chính xác khi sử dụng, pha chế và điều trị bằng hydrocodone bitart. Lỗi liều có thể dẫn đến quá liều và tử vong do sử dụng đồng thời với thuốc ức chế CYP3A4 (hoặc ngừng sử dụng thuốc gây cảm ứng CYP3A4) có thể dẫn đến quá liều hydrocodone. Tránh sử dụng hydrocodone bitartrate / guaifenesin ở những bệnh nhân sử dụng thuốc ức chế CYP3A4 hoặc thuốc gây cảm ứng. Sử dụng opioid với thuốc benzodiazepin hoặc thuốc ức chế hệ thần kinh trung ương (CNS) khác, bao gồm cả rượu, có thể dẫn đến trầm cảm, suy hô hấp, gây tử vong. Tránh sử dụng hydrocodone bitartrate / guaifenesin ở những bệnh nhân sử dụng thuốc benzodiazepin, thuốc ức chế thần kinh trung ương hoặc rượu khác. Hướng dẫn bệnh nhân không sử dụng rượu hoặc bất kỳ sản phẩm nào có chứa cồn trong khi uống hydrocodone bitartrate / guaifenesin / guaifenesin không được khuyến cáo sử dụng cho phụ nữ mang thai. Việc sử dụng hydrocodone bitartrate / guaifenesin trong thời gian mang thai có thể dẫn đến hội chứng cai nghiện opioid ở trẻ sơ sinh, có thể đe dọa đến tính mạng nếu không được công nhận và điều trị. Nếu hydrocodone bitartrate / guaifenesin được sử dụng trong một thời gian dài ở phụ nữ mang thai, khuyên bệnh nhân về nguy cơ mắc hội chứng cai nghiện opioid ở trẻ sơ sinh và đảm bảo sẽ có phương pháp điều trị thích hợp.

Đường uống (Máy tính bảng)

Nghiện, lạm dụng và lạm dụng: Viên nén Hydrocodone bitartrate và guaifenesin làm cho bệnh nhân và những người dùng khác gặp nguy cơ nghiện opioid, lạm dụng và lạm dụng, có thể dẫn đến quá liều và tử vong. Dự trữ viên hydrocodone bitartrate và guaifenesin để sử dụng cho bệnh nhân trưởng thành, những người mà lợi ích của việc giảm ho được dự kiến sẽ lớn hơn các rủi ro, và trong đó đánh giá đầy đủ về nguyên nhân của ho đã được thực hiện. Đánh giá rủi ro của từng bệnh nhân trước khi kê toa thuốc hydrocodone bitartrate và guaifenesin, kê toa thuốc hydrocodone bitartrate và guaifenesin trong thời gian ngắn nhất phù hợp với mục tiêu điều trị của từng bệnh nhân, theo dõi tất cả các bệnh nhân thường xuyên để phát triển thêm hoặc lạm dụng sự cần thiết phải tiếp tục điều trị. Suy giảm hô hấp đe dọa: Suy hô hấp nghiêm trọng, đe dọa tính mạng hoặc gây tử vong có thể xảy ra khi sử dụng hydrocodone bitartrate và viên guaifenesin. Theo dõi tình trạng suy hô hấp, đặc biệt là khi bắt đầu điều trị bằng hydrocodone bitartrate và guaifenesin hoặc khi sử dụng ở những bệnh nhân có nguy cơ cao hơn. Ăn uống vô tình của hydrocodone. Lỗi của thuốc Điều trị chính xác khi kê đơn, pha chế và quản lý hydrocodone bitartrate và máy tính bảng guaifenesin. Lỗi liều có thể dẫn đến quá liều và tử vong do tai nạn. Tương tác P450 3A4: Việc sử dụng đồng thời hydrocodone bitartrate và guaifenesin với tất cả các chất ức chế cytochrom P450 3A4 có thể dẫn đến tăng nồng độ trong huyết tương hydrocodone, có thể làm tăng hoặc kéo dài tác dụng phụ của thuốc và có thể gây ức chế hô hấp gây tử vong. Ngoài ra, việc ngừng sử dụng thuốc cảm ứng cytochrom P450 3A4 được sử dụng đồng thời có thể dẫn đến sự gia tăng nồng độ trong huyết tương hydrocodone. Tránh sử dụng viên nén hydrocodone bitartrate và guaifenesin ở những bệnh nhân sử dụng chất ức chế hoặc chất gây cảm ứng CYP3A4. trong an thần sâu sắc, suy hô hấp, hôn mê và tử vong. Tránh sử dụng viên nén hydrocodone bitartrate và guaifenesin ở những bệnh nhân sử dụng thuốc benzodiazepin, thuốc ức chế thần kinh trung ương khác hoặc rượu. . Việc uống rượu với hydrocodone bitartrate và viên guaifenesin có thể dẫn đến tăng nồng độ trong huyết tương và quá liều hydrocodone có thể gây tử vong. Việc sử dụng lâu dài hydrocodone bitartrate và viên guaifenesin trong thai kỳ có thể dẫn đến hội chứng cai nghiện opioid ở trẻ sơ sinh, có thể đe dọa đến tính mạng nếu không được nhận biết và điều trị, và cần được quản lý theo các phác đồ được phát triển bởi các chuyên gia sơ sinh. Nếu sử dụng viên hydrocodone bitartrate và guaifenesin trong thời gian dài ở phụ nữ mang thai, hãy khuyên bệnh nhân về nguy cơ mắc hội chứng cai nghiện opioid ở trẻ sơ sinh và đảm bảo sẽ có phương pháp điều trị thích hợp.

Holevn.org xem xét y tế. Cập nhật lần cuối vào ngày 22 tháng 11 năm 2019.

Tên thương hiệu CodiCLEAR DH đã bị ngừng sử dụng tại Hoa Kỳ Nếu các phiên bản chung của sản phẩm này đã được FDA chấp thuận, có thể có các loại tương đương chung.

Tên thương hiệu thường được sử dụng

Tại Hoa Kỳ

  • Cang-XP
  • CodiClear DH
  • ExeClear
  • Exe XP
  • Extendryl HC
  • FluTuss XP
  • HG-Tussin HG
  • Monte-G HC
  • Narcof
  • Pancof XP
  • Tussiclear DH
  • Tusso-HC

Các dạng bào chế có sẵn:

  • Giải pháp

Lớp trị liệu: Chống ho, Opioid / Expectorant

Lớp hóa học: Hydrocodone

Sử dụng cho CodiClear DH

Kết hợp Guaifenesin và hydrocodone được sử dụng để làm giảm ho và nghẹt mũi liên quan đến cảm lạnh thông thường.

Hydrocodone là một chất chống nôn gây nghiện (thuốc giảm ho). Nó tác động trực tiếp lên trung tâm ho trong não để giảm ho. Guaifenesin được sử dụng để giúp làm sạch chất nhầy hoặc đờm từ ngực khi bạn bị tắc nghẽn do cảm lạnh hoặc cúm. Nó hoạt động bằng cách làm loãng chất nhầy hoặc đờm trong phổi.

Thuốc này chỉ có sẵn với toa thuốc của bác sĩ.

Trước khi sử dụng CodiClear DH

Khi quyết định sử dụng thuốc, rủi ro của việc dùng thuốc phải được cân nhắc với lợi ích mà nó sẽ làm. Đây là một quyết định mà bạn và bác sĩ của bạn sẽ đưa ra. Đối với thuốc này, cần xem xét những điều sau đây:

Dị ứng

Hãy cho bác sĩ của bạn nếu bạn đã từng có bất kỳ phản ứng bất thường hoặc dị ứng với thuốc này hoặc bất kỳ loại thuốc khác. Cũng nói với chuyên gia chăm sóc sức khỏe của bạn nếu bạn có bất kỳ loại dị ứng nào khác, chẳng hạn như thực phẩm, thuốc nhuộm, chất bảo quản hoặc động vật. Đối với các sản phẩm không kê đơn, đọc nhãn hoặc thành phần gói cẩn thận.

Nhi khoa

Việc sử dụng hydrocodone ở trẻ em dưới 6 tuổi đã gây ra các vấn đề nghiêm trọng về hô hấp, đôi khi gây tử vong. Các nghiên cứu thích hợp đã không được thực hiện về mối quan hệ của tuổi tác với tác động của sự kết hợp guaifenesin và hydrocodone trong dân số nhi khoa. An toàn và hiệu quả chưa được thành lập.

Lão

Các nghiên cứu phù hợp được thực hiện cho đến nay đã không chứng minh được các vấn đề cụ thể về lão khoa sẽ hạn chế tính hữu ích của sự kết hợp guaifenesin và hydrocodone ở người cao tuổi. Tuy nhiên, bệnh nhân cao tuổi có nhiều khả năng phát triển các vấn đề về thận, gan hoặc tim liên quan đến tuổi, điều này có thể cần thận trọng và điều chỉnh liều cho bệnh nhân dùng thuốc này.

Cho con bú

Không có nghiên cứu đầy đủ ở phụ nữ để xác định nguy cơ trẻ sơ sinh khi sử dụng thuốc này trong thời gian cho con bú. Cân nhắc lợi ích tiềm năng chống lại các rủi ro tiềm ẩn trước khi dùng thuốc này trong khi cho con bú.

Tương tác với thuốc

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using this medicine.

Using this medication can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.

    Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal opioid withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.

    This medicine may cause adrenal insufficiency. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.

    If you have been using this medicine regularly for several weeks or longer, do not suddenly stop using it without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping.

    Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body.

    Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using the tablet if you plan to have children.

    Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

    CodiClear DH side effects

    Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Check with your doctor immediately if any of the following side effects occur:

    Incidence not known

    • Agitation
    • bladder pain
    • bloating or swelling of the face, arms, hands, lower legs, or feet
    • bloody or cloudy urine
    • changes in vision
    • chills
    • cough
    • darkening of the skin
    • diarrhea
    • difficult, burning, or painful urination
    • difficulty swallowing or breathing
    • dizziness
    • dizziness, faintness, or lightheadedness when getting up suddenly from lying or sitting position
    • fainting
    • fast heartbeat
    • frequent urge to urinate
    • hives, itching, skin rash
    • irregular, fast or slow, or shallow breathing
    • loss of appetite
    • loss of consciousness
    • mental depression
    • nausea
    • overactive reflexes
    • pains in stomach, side, or abdomen, possibly radiating to the back
    • pale or blue lips, fingernails, or skin
    • poor coordination
    • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    • rapid weight gain
    • restlessness shivering talking or acting with excitement you cannot control
    • tightness in the chest
    • tingling of the hands or feet
    • trembling or shaking twitching
    • unusual weight gain or loss
    • vomiting
    • yellow eyes or skin

    Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    More common

    • Diarrhea
    • difficulty having a bowel movement
    • feeling of warmth
    • headache
    • lack or loss of strength
    • nausea
    • redness of the face, neck, arms, and occasionally, upper chest
    • sleepiness or unusual drowsiness
    • stomach pain
    • sudden sweating
    • trouble sleeping

    Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    It is very important that your doctor check your progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your symptoms do not improve or if they get worse, call your doctor.

    It is against the law and dangerous for anyone else to use your medicine. Keep your unused oral liquid or tablets in a safe and secure place. People who are addicted to drugs might want to steal this medicine.

    Do not use this medicine if you are using or have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.

    This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

    If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Signs of an overdose include dark urine, difficult or troubled breathing, irregular, fast or slow, or shallow breathing, nausea or vomiting, pain in the upper stomach, pale or blue lips, fingernails, or skin, pinpoint pupils of the eyes, or yellow eyes or skin.

    This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

    This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using this medicine.

    Using this medication can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

    Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.

    Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal opioid withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.

    This medicine may cause adrenal insufficiency. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.

    If you have been using this medicine regularly for several weeks or longer, do not suddenly stop using it without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping.

    Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body.

    Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using the tablet if you plan to have children.

    Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

    CodiClear DH side effects

    Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Check with your doctor immediately if any of the following side effects occur:

    Incidence not known

    • Agitation
    • bladder pain
    • bloating or swelling of the face, arms, hands, lower legs, or feet
    • bloody or cloudy urine
    • changes in vision
    • chills
    • cough
    • darkening of the skin
    • diarrhea
    • difficult, burning, or painful urination
    • difficulty swallowing or breathing
    • dizziness
    • dizziness, faintness, or lightheadedness when getting up suddenly from lying or sitting position
    • fainting
    • fast heartbeat
    • frequent urge to urinate
    • hives, itching, skin rash
    • irregular, fast or slow, or shallow breathing
    • loss of appetite
    • loss of consciousness
    • mental depression
    • nausea
    • overactive reflexes
    • pains in stomach, side, or abdomen, possibly radiating to the back
    • pale or blue lips, fingernails, or skin
    • poor coordination
    • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    • rapid weight gain
    • restlessness shivering talking or acting with excitement you cannot control
    • tightness in the chest
    • tingling of the hands or feet
    • trembling or shaking twitching
    • unusual weight gain or loss
    • vomiting
    • yellow eyes or skin

    Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    More common

    • Diarrhea
    • difficulty having a bowel movement
    • feeling of warmth
    • headache
    • lack or loss of strength
    • nausea
    • redness of the face, neck, arms, and occasionally, upper chest
    • sleepiness or unusual drowsiness
    • stomach pain
    • sudden sweating
    • trouble sleeping

    Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    It is very important that your doctor check your progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your symptoms do not improve or if they get worse, call your doctor.

    It is against the law and dangerous for anyone else to use your medicine. Keep your unused oral liquid or tablets in a safe and secure place. People who are addicted to drugs might want to steal this medicine.

    Do not use this medicine if you are using or have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.

    This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

    If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Signs of an overdose include dark urine, difficult or troubled breathing, irregular, fast or slow, or shallow breathing, nausea or vomiting, pain in the upper stomach, pale or blue lips, fingernails, or skin, pinpoint pupils of the eyes, or yellow eyes or skin.

    This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

    This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using this medicine.

    Using this medication can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

    Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.

    Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal opioid withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.

    This medicine may cause adrenal insufficiency. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.

    If you have been using this medicine regularly for several weeks or longer, do not suddenly stop using it without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping.

    Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body.

    Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using the tablet if you plan to have children.

    Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

    CodiClear DH side effects

    Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

    Check with your doctor immediately if any of the following side effects occur:

    Incidence not known

    • Agitation
    • bladder pain
    • bloating or swelling of the face, arms, hands, lower legs, or feet
    • bloody or cloudy urine
    • changes in vision
    • chills
    • cough
    • darkening of the skin
    • diarrhea
    • difficult, burning, or painful urination
    • difficulty swallowing or breathing
    • dizziness
    • dizziness, faintness, or lightheadedness when getting up suddenly from lying or sitting position
    • fainting
    • fast heartbeat
    • frequent urge to urinate
    • hives, itching, skin rash
    • irregular, fast or slow, or shallow breathing
    • loss of appetite
    • loss of consciousness
    • mental depression
    • nausea
    • overactive reflexes
    • pains in stomach, side, or abdomen, possibly radiating to the back
    • pale or blue lips, fingernails, or skin
    • poor coordination
    • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    • rapid weight gain
    • restlessness shivering talking or acting with excitement you cannot control
    • tightness in the chest
    • tingling of the hands or feet
    • trembling or shaking twitching
    • unusual weight gain or loss
    • vomiting
    • yellow eyes or skin

    Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    More common

    • Diarrhea
    • difficulty having a bowel movement
    • feeling of warmth
    • headache
    • lack or loss of strength
    • nausea
    • redness of the face, neck, arms, and occasionally, upper chest
    • sleepiness or unusual drowsiness
    • stomach pain
    • sudden sweating
    • trouble sleeping

    Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

    Seek emergency medical attention or call 115

    Further information

    The content of Holevn is solely for the purpose of providing information about Thuốc CodiClear DH (Oral)  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

    Reference from: https://www.drugs.com/cons/codiclear-dh.html

  • Dextromethorphan
  • Dezocine
  • Diazepam
  • Dibenzepin
  • Dichloralphenazone
  • Difenoxin
  • Dihydrocodeine
  • Diltiazem
  • Diphenhydramine
  • Diphenoxylate
  • Dolasetron
  • Donepezil
  • Doxepin
  • Doxylamine
  • Dronedarone
  • Droperidol
  • Duloxetine
  • Efavirenz
  • Eletriptan
  • Enflurane
  • Enzalutamide
  • Erythromycin
  • Escitalopram
  • Esketamine
  • Eslicarbazepine Acetate
  • Estazolam
  • Eszopiclone
  • Ethchlorvynol
  • Ethopropazine
  • Ethylmorphine
  • Etravirine
  • Fentanyl
  • Flibanserin
  • Fluconazole
  • Fluoxetine
  • Fluphenazine
  • Flurazepam
  • Fluspirilene
  • Fluvoxamine
  • Fosamprenavir
  • Fosaprepitant
  • Fosnetupitant
  • Fosphenytoin
  • Fospropofol
  • Frovatriptan
  • Furazolidone
  • Gabapentin
  • Gabapentin Enacarbil
  • Granisetron
  • Halazepam
  • Haloperidol
  • Halothane
  • Hexobarbital
  • Hydromorphone
  • Hydroxytryptophan
  • Hydroxyzine
  • Idelalisib
  • Imatinib
  • Imipramine
  • Indinavir
  • Iproniazid
  • Isocarboxazid
  • Isoflurane
  • Itraconazole
  • Ivacaftor
  • Ketamine
  • Ketazolam
  • Ketobemidone
  • Ketoconazole
  • Lasmiditan
  • Levomilnacipran
  • Levorphanol
  • Linezolid
  • Lisdexamfetamine
  • Lithium
  • Lofepramine
  • Lofexidine
  • Lomitapide
  • Lopinavir
  • Lorazepam
  • Lorcaserin
  • Loxapine
  • Lumacaftor
  • Meclizine
  • Melitracen
  • Melperone
  • Meperidine
  • Mephobarbital
  • Meprobamate
  • Meptazinol
  • Mesoridazine
  • Metaxalone
  • Methadone
  • Methamphetamine
  • Methdilazine
  • Methocarbamol
  • Methohexital
  • Methotrimeprazine
  • Methylene Blue
  • Metoclopramide
  • Mibefradil
  • Midazolam
  • Mifepristone
  • Milnacipran
  • Mirtazapine
  • Mitotane
  • Moclobemide
  • Modafinil
  • Molindone
  • Moricizine
  • Morphine
  • Morphine Sulfate Liposome
  • Nafcillin
  • Nalbuphine
  • Naratriptan
  • Nefazodone
  • Nelfinavir
  • Netupitant
  • Nevirapine
  • Nialamide
  • Nicomorphine
  • Nilotinib
  • Nitrazepam
  • Nitrous Oxide
  • Nortriptyline
  • Olanzapine
  • Ombitasvir
  • Ondansetron
  • Opipramol
  • Opium
  • Opium Alkaloids
  • Orphenadrine
  • Oxazepam
  • Oxcarbazepine
  • Oxycodone
  • Oxymorphone
  • Palbociclib
  • Palonosetron
  • Papaveretum
  • Paregoric
  • Paritaprevir
  • Paroxetine
  • Pentazocine
  • Pentobarbital
  • Perampanel
  • Perazine
  • Periciazine
  • Perphenazine
  • Phenelzine
  • Phenobarbital
  • Phenytoin
  • Piperacetazine
  • Pipotiazine
  • Piritramide
  • Posaconazole
  • Prazepam
  • Prednisone
  • Pregabalin
  • Primidone
  • Procarbazine
  • Prochlorperazine
  • Promazine
  • Promethazine
  • Propofol
  • Protriptyline
  • Quazepam
  • Quetiapine
  • Ramelteon
  • Ranitidine
  • Ranolazine
  • Rasagiline
  • Remifentanil
  • Remoxipride
  • Rifabutin
  • Rifampin
  • Rifapentine
  • Ritonavir
  • Rizatriptan
  • Saquinavir
  • Scopolamine
  • Secobarbital
  • Selegiline
  • Sertindole
  • Sertraline
  • Sibutramine
  • Sodium Oxybate
  • St John’s Wort
  • Sufentanil
  • Sulpiride
  • Sumatriptan
  • Suvorexant
  • Tapentadol
  • Telaprevir
  • Telithromycin
  • Temazepam
  • Thiethylperazine
  • Thiopental
  • Thiopropazate
  • Thioridazine
  • Tianeptine
  • Tilidine
  • Tizanidine
  • Tolonium Chloride
  • Topiramate
  • Tramadol
  • Tranylcypromine
  • Trazodone
  • Triazolam
  • Trifluoperazine
  • Trifluperidol
  • Triflupromazine
  • Trimeprazine
  • Trimipramine
  • Tryptophan
  • Venlafaxine
  • Verapamil
  • Vilazodone
  • Voriconazole
  • Vortioxetine
  • Zaleplon
  • Ziprasidone
  • Zolmitriptan
  • Zolpidem
  • Zopiclone
  • Zotepine

Interactions with food/tobacco/alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.

Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.

  • Ethanol
  • Grapefruit Juice

Other medical problems

The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:

  • Acute pancreatitis (swelling of the pancreas) or
  • Addison’s disease (adrenal problem) or
  • Alcohol abuse, or history of or
  • Brain tumor, history of or
  • Breathing problems, severe (eg, hypoxia, hypercapnia) or
  • Chronic obstructive pulmonary disease (COPD) or
  • CNS depression or
  • Cor pulmonale (serious heart condition) or
  • Diabetes or
  • Drug abuse or dependence, especially with narcotics, or history of or
  • Enlarged prostate or
  • Gallbladder disease or
  • Head injuries or
  • Increased pressure in the head or
  • Mental health problems, history of or
  • Stomach problems or
  • Thyroid problems or
  • Trouble urinating—Use with caution. May increase risk for more serious side effects.
  • Asthma, acute or severe or
  • Cough, chronic or persistent or
  • Paralytic ileus (bowels stop working and may be blocked), known or suspected or
  • Respiratory depression (very slow breathing)—Should not be used in patients with these conditions.
  • Hypotension (low blood pressure)—Use with caution. May make this condition worse.
  • Kidney disease, severe or
  • Liver disease, severe—Use with caution. May make these conditions worse.

Proper use of CodiClear DH

This section provides information on the proper use of a number of products that contain guaifenesin and hydrocodone. It may not be specific to CodiClear DH. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Measure the oral liquid correctly using the marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Ask your pharmacist for instructions for measuring the correct dose of this medicine.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For relief of cough, sneezing, or runny or stuffy nose:
    • For oral dosage form (solution):
      • Adults—10 milliliters (mL) every 4 to 6 hours as needed. Do not take more than 6 doses (60 mL) in 24 hours.
      • Children—Use and dose must be determined by your doctor.
    • For oral dosage form (tablets):
      • Adults—1 tablet every 4 to 6 hours. Do not take more than 6 tablets in 24 hours.
      • Children—Use and dose must be determined by your doctor.

Missed dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm

Precautions while using CodiClear DH

It is very important that your doctor check your progress while you are using this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your symptoms do not improve or if they get worse, call your doctor.

It is against the law and dangerous for anyone else to use your medicine. Keep your unused oral liquid or tablets in a safe and secure place. People who are addicted to drugs might want to steal this medicine.

Do not use this medicine if you are using or have used an MAO inhibitor (MAOI) such as Eldepryl®, Marplan®, Nardil®, or Parnate® within the past 14 days.

This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.

If you think you or someone else may have taken an overdose of this medicine, get emergency help at once. Signs of an overdose include dark urine, difficult or troubled breathing, irregular, fast or slow, or shallow breathing, nausea or vomiting, pain in the upper stomach, pale or blue lips, fingernails, or skin, pinpoint pupils of the eyes, or yellow eyes or skin.

This medicine may make you dizzy or drowsy. Do not drive or do anything else that could be dangerous until you know how this medicine affects you.

This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using this medicine.

Using this medication can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.

Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.

Using this medicine while you are pregnant may cause serious unwanted effects, including neonatal opioid withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.

This medicine may cause adrenal insufficiency. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.

If you have been using this medicine regularly for several weeks or longer, do not suddenly stop using it without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping.

Check with your doctor right away if you have anxiety, restlessness, a fast heartbeat, fever, sweating, muscle spasms, twitching, nausea, vomiting, diarrhea, or see or hear things that are not there. These may be symptoms of a serious condition called serotonin syndrome. Your risk may be higher if you also take certain other medicines that affect serotonin levels in your body.

Using too much of this medicine may cause infertility (unable to have children). Talk with your doctor before using the tablet if you plan to have children.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

CodiClear DH side effects

Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur:

Incidence not known

  • Agitation
  • bladder pain
  • bloating or swelling of the face, arms, hands, lower legs, or feet
  • bloody or cloudy urine
  • changes in vision
  • chills
  • cough
  • darkening of the skin
  • diarrhea
  • difficult, burning, or painful urination
  • difficulty swallowing or breathing
  • dizziness
  • dizziness, faintness, or lightheadedness when getting up suddenly from lying or sitting position
  • fainting
  • fast heartbeat
  • frequent urge to urinate
  • hives, itching, skin rash
  • irregular, fast or slow, or shallow breathing
  • loss of appetite
  • loss of consciousness
  • mental depression
  • nausea
  • overactive reflexes
  • pains in stomach, side, or abdomen, possibly radiating to the back
  • pale or blue lips, fingernails, or skin
  • poor coordination
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rapid weight gain
  • restlessness shivering talking or acting with excitement you cannot control
  • tightness in the chest
  • tingling of the hands or feet
  • trembling or shaking twitching
  • unusual weight gain or loss
  • vomiting
  • yellow eyes or skin

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common

  • Diarrhea
  • difficulty having a bowel movement
  • feeling of warmth
  • headache
  • lack or loss of strength
  • nausea
  • redness of the face, neck, arms, and occasionally, upper chest
  • sleepiness or unusual drowsiness
  • stomach pain
  • sudden sweating
  • trouble sleeping

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Seek emergency medical attention or call 115

Further information

The content of Holevn is solely for the purpose of providing information about Thuốc CodiClear DH (Oral)  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/cons/codiclear-dh.html

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