Thuốc Cholic acid

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Thuốc Cholic acid
Thuốc Cholic acid

Initial dose: 10 to 15 mg/kg orally once a day or in 2 divided doses

Patients with Concomitant Familial Hypertriglyceridemia:
Initial dose: 11 to 17 mg/kg orally once a day or in 2 divided doses

Maintenance dose: The lowest dose that effectively maintains liver function

Comments:
-Adequacy of dosing should be determined by patient monitoring of clinical response and laboratory values; monitor more frequently during periods of rapid growth, concomitant disease, and pregnancy
-Concurrent elevations of serum gamma glutamyltransferase (GGT) and ALT may indicate cholic acid overdose.

Uses:
-For the treatment of bile acid synthesis disorders due to single enzyme defects
-As adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea, or complications from decreased fat soluble vitamin absorption.

Usual Pediatric Dose for Bile Acid Synthesis Disorders:

Initial dose: 10 to 15 mg/kg orally once a day or in 2 divided doses

Patients with Concomitant Familial Hypertriglyceridemia:
Initial dose: 11 to 17 mg/kg orally once a day or in 2 divided doses

Maintenance dose: The lowest dose that effectively maintains liver function

Comments:
-Adequacy of dosing should be determined by patient monitoring of clinical response and laboratory values; monitor more frequently during periods of rapid growth, concomitant disease, and pregnancy
-Concurrent elevations of serum gamma glutamyltransferase (GGT) and ALT may indicate cholic acid overdose.

Uses:
-For the treatment of bile acid synthesis disorders due to single enzyme defects
-As adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea, or complications from decreased fat soluble vitamin absorption.

What other drugs will affect cholic acid?

Other drugs may interact with cholic acid, including prescription and over-the-counter medicines, vitamins, and . Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

The content of Holevn is solely for the purpose of providing information about Thuốc Cholic acid  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/mtm/cholic-acid.html

Before taking this medicine

To make sure cholic acid is safe for you, tell your doctor if you have:

  • liver disease; or

  • if you also use .

It is not known whether cholic acid will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry. This is to track the outcome of the pregnancy and to evaluate any effects of cholic acid on the baby.

Cholic acid can pass into breast milk and may harm a nursing baby. Tell your doctor if you are breast-feeding a baby.

Do not give this medicine to a child without medical advice. Cholic acid is not approved for use by anyone younger than 3 weeks old.

How should I take cholic acid?

Follow all directions on your prescription label. Do not use this medicine in larger or smaller amounts or for longer than recommended.

Cholic acid works best if you take it with food.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions.

Do not crush or chew a cholic acid capsule.

To make swallowing easier, you may open the cholic acid capsule and sprinkle the medicine into a spoonful of soft food. If you are giving cholic acid to a young child, mix the medicine with a small amount of baby formula or breast milk. Stir the mixture for 30 seconds and use it right away. Do not save the mixture for later use.

Cholic acid comes in different capsule sizes. Your dose may require that you take only 1 capsule per day or up to 8 capsules per day. Cholic acid doses are based on weight and you may need to use two different capsule sizes to make up your entire dose. Follow your doctor’s dosing instructions very carefully.

The recommended dose of cholic acid increases with every few pounds gained as you grow from infancy to adulthood. Tell your doctor if you have any changes in weight.

While using cholic acid, you may need frequent blood tests.

Store at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call 115.

What should I avoid while taking cholic acid?

When you take your cholic acid dose, avoid taking other medicines by mouth at the same time. Since cholic acid aids in digestion, it can affect how well your body absorbs any other medicines you need to take. Take cholic acid at least 1 hour before or 4 to 6 hours after you take:

  • ;

  • ;

  • ; or

  • an antacid that contains aluminum–Acid Gone, , , , Maalox, Mylagen, , , and others.

Cholic acid side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • blood in your stools, changes in your bowel habits (such as diarrhea or constipation);

  • pain or burning when you urinate; or

  • liver problems–nausea, upper stomach pain, itching, tired feeling, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes).

Common side effects may include:

  • heartburn, acid reflux;

  • nausea, diarrhea, stomach pain;

  • general ill feeling;

  • jaundice;

  • skin sores; or

  • numbness, tingling, or burning pain in your hands or feet.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Cholic acid dosing information

Usual Adult Dose for Bile Acid Synthesis Disorders:

Initial dose: 10 to 15 mg/kg orally once a day or in 2 divided doses

Patients with Concomitant Familial Hypertriglyceridemia:
Initial dose: 11 to 17 mg/kg orally once a day or in 2 divided doses

Maintenance dose: The lowest dose that effectively maintains liver function

Comments:
-Adequacy of dosing should be determined by patient monitoring of clinical response and laboratory values; monitor more frequently during periods of rapid growth, concomitant disease, and pregnancy
-Concurrent elevations of serum gamma glutamyltransferase (GGT) and ALT may indicate cholic acid overdose.

Uses:
-For the treatment of bile acid synthesis disorders due to single enzyme defects
-As adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea, or complications from decreased fat soluble vitamin absorption.

Usual Pediatric Dose for Bile Acid Synthesis Disorders:

Initial dose: 10 to 15 mg/kg orally once a day or in 2 divided doses

Patients with Concomitant Familial Hypertriglyceridemia:
Initial dose: 11 to 17 mg/kg orally once a day or in 2 divided doses

Maintenance dose: The lowest dose that effectively maintains liver function

Comments:
-Adequacy of dosing should be determined by patient monitoring of clinical response and laboratory values; monitor more frequently during periods of rapid growth, concomitant disease, and pregnancy
-Concurrent elevations of serum gamma glutamyltransferase (GGT) and ALT may indicate cholic acid overdose.

Uses:
-For the treatment of bile acid synthesis disorders due to single enzyme defects
-As adjunctive treatment of peroxisomal disorders including Zellweger spectrum disorders in patients who exhibit manifestations of liver disease, steatorrhea, or complications from decreased fat soluble vitamin absorption.

What other drugs will affect cholic acid?

Other drugs may interact with cholic acid, including prescription and over-the-counter medicines, vitamins, and . Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

The content of Holevn is solely for the purpose of providing information about Thuốc Cholic acid  and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.

Reference from: https://www.drugs.com/mtm/cholic-acid.html

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