Hovevn Health chia sẻ các bài viết về: Thuốc chlorpheniramine và codeine polistirex (Thuốc uống), tác dụng phụ – liều lượng, Thuốc chlorpheniramine và codein polistirex (Thuốc uống) điều trị bệnh gì. Vui lòng tham khảo các chi tiết dưới đây.
KOE-deen pol-ee-STYE-rex, klor-fen-IR-a-meen pol-ee-STYE-rex
Đường uống (Đình chỉ, Phát hành mở rộng)
Cảnh báo: Nghiện, Lạm dụng và Lạm dụng; Suy hô hấp đe dọa tính mạng, Nuốt phải tai nạn, Chuyển hóa cực nhanh của Codein và các yếu tố nguy cơ khác đối với Suy hô hấp đe dọa tính mạng ở trẻ em; Lỗi thuốc; Tương tác với các loại thuốc ảnh hưởng đến Cytochrom P450 3A4; Sử dụng đồng thời với thuốc Benzodiazepin hoặc thuốc ức chế thần kinh trung ương khác; Hội chứng rút Opioid sơ sinhCodeine polistirex / chlorpheniramine polistirex khiến người dùng có nguy cơ nghiện, lạm dụng và lạm dụng, có thể dẫn đến quá liều và tử vong. Đánh giá nguy cơ của bệnh nhân trước khi kê đơn và theo dõi chặt chẽ các hành vi và tình trạng này. Có thể xảy ra trầm cảm, đe dọa tính mạng hoặc suy hô hấp gây tử vong. Theo dõi chặt chẽ, đặc biệt là khi bắt đầu hoặc khi sử dụng ở những bệnh nhân có nguy cơ cao hơn. Việc sử dụng codein polistirex / chlorpheniramine polistirex, đặc biệt là ở trẻ em, có thể dẫn đến quá liều codein gây tử vong. codein; hầu hết các trường hợp sau phẫu thuật cắt amidan và / hoặc phẫu thuật cắt bỏ, và nhiều trẻ em đã có bằng chứng là một chất chuyển hóa cực nhanh của codein do đa hình CYP2D6. Codeine polistirex / chlorpheniramine polistirex chống chỉ định ở trẻ dưới 12 tuổi và ở trẻ dưới 18 tuổi sau phẫu thuật cắt amidan và / hoặc cắt điện từ. Tránh sử dụng codein polistirex / chlorpheniramine polistirex ở thanh thiếu niên từ 12 đến 18 tuổi, những người có các yếu tố nguy cơ khác có thể làm tăng độ nhạy cảm của chúng đối với các tác dụng ức chế hô hấp của codeine. Lỗi liều có thể dẫn đến quá liều và tử vong do tai nạn.
- Scopolamine
- Secobarbital
- Secretin Human
- Sertindole
- Sertraline
- Sibutramine
- Sodium Oxybate
- St John’s Wort
- Sufentanil
- Sulpiride
- Sumatriptan
- Suvorexant
- Tapentadol
- Telaprevir
- Telithromycin
- Temazepam
- Terbinafine
- Thiethylperazine
- Thiopental
- Thiopropazate
- Thioridazine
- Tianeptine
- Tilidine
- Tiotropium
- Tizanidine
- Tolonium Chloride
- Topiramate
- Tramadol
- Trazodone
- Triazolam
- Trifluoperazine
- Trifluperidol
- Triflupromazine
- Trimeprazine
- Trimipramine
- Tryptophan
- Venlafaxine
- Verapamil
- Vilazodone
- Voriconazole
- Vortioxetine
- Zaleplon
- Ziprasidone
- Zolmitriptan
- Zolpidem
- Zopiclone
- Zotepine
- Ethanol
- Acute pancreatitis (swelling of the pancreas) or
- Alcohol abuse, or history of or
- Addison’s disease (adrenal gland problem) or
- Brain tumor, history of or
- Drug dependence, especially with narcotics, or history of or
- Enlarged prostate (BPH, prostatic hypertrophy) or
- Gallbladder disease or
- Head injury, history of or
- Hypothyroidism (underactive thyroid), severe or
- Increased pressure in the head or
- Lung or breathing problems (eg, COPD) or
- Trouble urinating—May cause side effects to become worse.
- Asthma, acute or severe or
- Paralytic ileus (stomach or bowel blockage), known or suspected or
- Respiratory depression (very slow breathing)—Should not be used in patients with these conditions.
- Hypotension (low blood pressure)—Use with caution. May make this condition worse.
- Kidney disease, severe or
- Liver disease, severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
- For oral dosage form (extended-release suspension):
- For relief of cough and cold or allergy symptoms:
- Adults—10 milliliters (mL) every 12 hours as needed. Do not take more than 20 mL in 24 hours.
- Children—Use and dose must be determined by your doctor.
- For relief of cough and cold or allergy symptoms:
- Talk to your doctor if you have any questions about taking codeine or about how chlorpheniramine and codeine polistirex may affect your baby.
- Call your doctor if you become extremely tired and have difficulty caring for your baby.
- Your baby should generally nurse every 2 to 3 hours and should not sleep more than 4 hours at a time.
- Check with your doctor, hospital emergency room, or local emergency services (eg, “call 9-1-1”) immediately if your baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, difficulty breathing, or limpness. These may be symptoms of an overdose and need immediate medical attention.
- Anxiety
- belching
- bloating
- blurred or loss of vision
- chills
- cold, clammy skin
- cold sweat
- confusion
- dark urine
- depression
- diarrhea
- difficult or painful urination
- disturbed color perception
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- double vision
- dryness or spasm of the throat
- feeling of constant movement of self or surroundings
- fever
- halos around lights
- headache
- heartburn
- increased hunger
- indigestion
- irregular, fast or slow, or shallow breathing
- loss of appetite
- nausea
- nervousness
- night blindness
- nightmares
- overbright appearance of lights
- pain in the stomach, side, or abdomen, possibly radiating to the back
- pain or discomfort in the chest, upper stomach, or throat
- pale or blue lips, fingernails, or skin
- pressure in the stomach
- pounding in the ears
- seizures
- sensation of spinning
- shakiness
- sleepiness or unusual drowsiness
- slow, fast, or irregular heartbeat
- slurred speech
- stomach discomfort, upset, or pain
- sweating
- tunnel vision
- unusual tiredness or weakness
- vomiting
- yellow eyes or skin
- Anxiety
- blistering, crusting, or irritation of the skin
- continuing ringing or buzzing or other unexplained noise in the ears
- cracked, dry, scaly skin
- dry mouth
- early menstrual periods
- face is warm or hot to touch
- false or unusual sense of well-being
- general feeling of discomfort or illness
- hearing loss
- hiccups
- increased appetite
- increased in sexual ability, desire, drive, or performance
- increased interest in sexual intercourse
- irritability
- lack or loss of strength
- redness of the face
- restlessness
- skin rash, itching, redness, hives, swelling
- swelling of the breasts or breast soreness in both females and males
- trouble sleeping
- twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
- watering of the eyes
- Fluvoxamine
- Fosamprenavir
- Fosaprepitant
- Fosnetupitant
- Fosphenytoin
- Fospropofol
- Frovatriptan
- Gabapentin
- Gabapentin Enacarbil
- Glycopyrrolate
- Glycopyrronium Tosylate
- Granisetron
- Haloperidol
- Halothane
- Hexobarbital
- Hydrocodone
- Hydromorphone
- Hydroxytryptophan
- Hydroxyzine
- Idelalisib
- Imatinib
- Imipramine
- Indinavir
- Isoflurane
- Itraconazole
- Ivacaftor
- Ketamine
- Ketazolam
- Ketobemidone
- Ketoconazole
- Lasmiditan
- Levomilnacipran
- Levorphanol
- Lisdexamfetamine
- Lithium
- Lofepramine
- Lofexidine
- Lomitapide
- Lopinavir
- Lorazepam
- Lorcaserin
- Loxapine
- Lumacaftor
- Meclizine
- Melitracen
- Melperone
- Meperidine
- Mephobarbital
- Meprobamate
- Meptazinol
- Mesoridazine
- Metaxalone
- Methacholine
- Methadone
- Methamphetamine
- Methdilazine
- Methocarbamol
- Methohexital
- Methotrimeprazine
- Methylene Blue
- Metoclopramide
- Mibefradil
- Midazolam
- Mifepristone
- Milnacipran
- Mirabegron
- Mirtazapine
- Mitotane
- Modafinil
- Molindone
- Moricizine
- Morphine
- Morphine Sulfate Liposome
- Nafcillin
- Nalbuphine
- Naratriptan
- Nefazodone
- Nelfinavir
- Netupitant
- Nevirapine
- Nicomorphine
- Nilotinib
- Nitrazepam
- Nitrous Oxide
- Nortriptyline
- Olanzapine
- Ondansetron
- Opipramol
- Opium
- Opium Alkaloids
- Orphenadrine
- Oxazepam
- Oxcarbazepine
- Oxycodone
- Oxymorphone
- Palbociclib
- Palonosetron
- Papaveretum
- Paregoric
- Paroxetine
- Pentazocine
- Pentobarbital
- Perampanel
- Perazine
- Periciazine
- Perphenazine
- Phenobarbital
- Phenytoin
- Piperacetazine
- Pipotiazine
- Piritramide
- Pitolisant
- Posaconazole
- Prazepam
- Prednisone
- Pregabalin
- Primidone
- Prochlorperazine
- Promazine
- Promethazine
- Propofol
- Protriptyline
- Quazepam
- Quetiapine
- Quinidine
- Quinine
- Ramelteon
- Ranitidine
- Ranolazine
- Remifentanil
- Remoxipride
- Revefenacin
- Rifabutin
- Rifampin
- Rifapentine
- Ritonavir
- Rizatriptan
- Rolapitant
- Saquinavir
- Scopolamine
- Secobarbital
- Secretin Human
- Sertindole
- Sertraline
- Sibutramine
- Sodium Oxybate
- St John’s Wort
- Sufentanil
- Sulpiride
- Sumatriptan
- Suvorexant
- Tapentadol
- Telaprevir
- Telithromycin
- Temazepam
- Terbinafine
- Thiethylperazine
- Thiopental
- Thiopropazate
- Thioridazine
- Tianeptine
- Tilidine
- Tiotropium
- Tizanidine
- Tolonium Chloride
- Topiramate
- Tramadol
- Trazodone
- Triazolam
- Trifluoperazine
- Trifluperidol
- Triflupromazine
- Trimeprazine
- Trimipramine
- Tryptophan
- Venlafaxine
- Verapamil
- Vilazodone
- Voriconazole
- Vortioxetine
- Zaleplon
- Ziprasidone
- Zolmitriptan
- Zolpidem
- Zopiclone
- Zotepine
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using chlorpheniramine and codeine polistirex with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use chlorpheniramine and codeine polistirex, or give you special instructions about the use of food, alcohol, or tobacco.
Other medical problems
The presence of other medical problems may affect the use of chlorpheniramine and codeine polistirex. Make sure you tell your doctor if you have any other medical problems, especially:
Proper use of chlorpheniramine and codeine polistirex
Take chlorpheniramine and codeine polistirex only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of chlorpheniramine and codeine polistirex is taken for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.
Chlorpheniramine and codeine polistirex comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.
You may take chlorpheniramine and codeine polistirex with or without food.
Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Shake the medicine well before you use it.
Dosing
The dose of chlorpheniramine and codeine polistirex will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of chlorpheniramine and codeine polistirex. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
Missed dose
If you miss a dose of chlorpheniramine and codeine polistirex, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm
Precautions while using chlorpheniramine and codeine polistirex
It is very important that your doctor check your progress while you are using chlorpheniramine and codeine polistirex. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your cough does not improve or if it gets worse within 5 days, call your doctor.
Do not use chlorpheniramine and codeine polistirex if you are using or have used an MAO inhibitor (MAOI) such as isocarboxazid [Marplan®], linezolid [Zyvox®], phenelzine [Nardil®], selegiline [Eldepryl®], tranylcypromine [Parnate®]) within the past 14 days.
Chlorpheniramine and codeine polistirex may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
Do not change your dose or suddenly stop using chlorpheniramine and codeine polistirex without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.
Codeine is changed to morphine in the body. Some people change codeine to morphine more quickly than others. These individuals are called “ultra-rapid metabolizers of codeine”. Contact your doctor immediately if you experience extreme sleepiness, confusion, or shallow breathing. These symptoms may indicate that you are an “ultra-rapid metabolizer of codeine”. As a result, there is too much morphine in the body and more side effects of morphine than usual. Children may be especially sensitive to this effect (eg, serious breathing problems, death). Do not give chlorpheniramine and codeine polistirex to children 12 to 18 years of age who have had surgery removal of tonsils or adenoids.
If a nursing mother is an ultra-rapid metabolizer of codeine, it could lead to a morphine overdose in the nursing baby and cause very serious side effects.
For nursing mothers taking chlorpheniramine and codeine polistirex:
Using chlorpheniramine and codeine polistirex while you are pregnant may cause serious unwanted effects, including neonatal opioid withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using chlorpheniramine and codeine polistirex.
Using chlorpheniramine and codeine polistirex can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.
Chlorpheniramine and codeine polistirex may make you confused, dizzy, or drowsy. Do not drive or do anything else that could be dangerous until you know how chlorpheniramine and codeine polistirex affects you.
Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.
Chlorpheniramine and codeine polistirex will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using chlorpheniramine and codeine polistirex.
If you think you or someone else may have taken an overdose of chlorpheniramine and codeine polistirex, get emergency help at once. Signs of an overdose include: pale or blue lips, fingernails, or skin, confusion, difficult or troubled breathing, irregular, fast or slow, or shallow breathing, extreme sleepiness or drowsiness, cold and clammy skin, or lightheadedness or fainting.
Chlorpheniramine and codeine polistirex may cause adrenal insufficiency. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.
If you are especially sensitive to the effects of chlorpheniramine and codeine polistirex, do not suddenly stop using it without first checking with your doctor Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping.
Using too much of chlorpheniramine and codeine polistirex may cause infertility (unable to have children). Talk with your doctor before using chlorpheniramine and codeine polistirex if you plan to have children.
Make sure any doctor or dentist who treats you knows that you are using chlorpheniramine and codeine polistirex.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Chlorpheniramine and codeine polistirex side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Seek emergency medical attention or call 115
Further information
Copyright 2020 Truven Health Analytics, Inc. All Rights Reserved.
Medical Disclaimer
The content of Holevn is solely for the purpose of providing information about Thuốc Chlorpheniramine and codeine polistirex (Oral) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/cons/chlorpheniramine-and-codeine-polistirex.html
Interactions with food/tobacco/alcohol
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using chlorpheniramine and codeine polistirex with any of the following may cause an increased risk of certain side effects but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use chlorpheniramine and codeine polistirex, or give you special instructions about the use of food, alcohol, or tobacco.
- Ethanol
Other medical problems
The presence of other medical problems may affect the use of chlorpheniramine and codeine polistirex. Make sure you tell your doctor if you have any other medical problems, especially:
- Acute pancreatitis (swelling of the pancreas) or
- Alcohol abuse, or history of or
- Addison’s disease (adrenal gland problem) or
- Brain tumor, history of or
- Drug dependence, especially with narcotics, or history of or
- Enlarged prostate (BPH, prostatic hypertrophy) or
- Gallbladder disease or
- Head injury, history of or
- Hypothyroidism (underactive thyroid), severe or
- Increased pressure in the head or
- Lung or breathing problems (eg, COPD) or
- Trouble urinating—May cause side effects to become worse.
- Asthma, acute or severe or
- Paralytic ileus (stomach or bowel blockage), known or suspected or
- Respiratory depression (very slow breathing)—Should not be used in patients with these conditions.
- Hypotension (low blood pressure)—Use with caution. May make this condition worse.
- Kidney disease, severe or
- Liver disease, severe—Use with caution. The effects may be increased because of slower removal of the medicine from the body.
Proper use of chlorpheniramine and codeine polistirex
Take chlorpheniramine and codeine polistirex only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of chlorpheniramine and codeine polistirex is taken for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.
Chlorpheniramine and codeine polistirex comes with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.
You may take chlorpheniramine and codeine polistirex with or without food.
Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid. Shake the medicine well before you use it.
Dosing
The dose of chlorpheniramine and codeine polistirex will be different for different patients. Follow your doctor’s orders or the directions on the label. The following information includes only the average doses of chlorpheniramine and codeine polistirex. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
- For oral dosage form (extended-release suspension):
- For relief of cough and cold or allergy symptoms:
- Adults—10 milliliters (mL) every 12 hours as needed. Do not take more than 20 mL in 24 hours.
- Children—Use and dose must be determined by your doctor.
- For relief of cough and cold or allergy symptoms:
Missed dose
If you miss a dose of chlorpheniramine and codeine polistirex, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Storage
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Drop off any unused narcotic medicine at a drug take-back location right away. If you do not have a drug take-back location near you, flush any unused narcotic medicine down the toilet. Check your local drug store and clinics for take-back locations. You can also check the DEA web site for locations. Here is the link to the FDA safe disposal of medicines website: www.fda.gov/drugs/resourcesforyou/consumers/buyingusingmedicinesafely/ensuringsafeuseofmedicine/safedisposalofmedicines/ucm186187.htm
Precautions while using chlorpheniramine and codeine polistirex
It is very important that your doctor check your progress while you are using chlorpheniramine and codeine polistirex. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. If your cough does not improve or if it gets worse within 5 days, call your doctor.
Do not use chlorpheniramine and codeine polistirex if you are using or have used an MAO inhibitor (MAOI) such as isocarboxazid [Marplan®], linezolid [Zyvox®], phenelzine [Nardil®], selegiline [Eldepryl®], tranylcypromine [Parnate®]) within the past 14 days.
Chlorpheniramine and codeine polistirex may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
Do not change your dose or suddenly stop using chlorpheniramine and codeine polistirex without first checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.
Codeine is changed to morphine in the body. Some people change codeine to morphine more quickly than others. These individuals are called “ultra-rapid metabolizers of codeine”. Contact your doctor immediately if you experience extreme sleepiness, confusion, or shallow breathing. These symptoms may indicate that you are an “ultra-rapid metabolizer of codeine”. As a result, there is too much morphine in the body and more side effects of morphine than usual. Children may be especially sensitive to this effect (eg, serious breathing problems, death). Do not give chlorpheniramine and codeine polistirex to children 12 to 18 years of age who have had surgery removal of tonsils or adenoids.
If a nursing mother is an ultra-rapid metabolizer of codeine, it could lead to a morphine overdose in the nursing baby and cause very serious side effects.
For nursing mothers taking chlorpheniramine and codeine polistirex:
- Talk to your doctor if you have any questions about taking codeine or about how chlorpheniramine and codeine polistirex may affect your baby.
- Call your doctor if you become extremely tired and have difficulty caring for your baby.
- Your baby should generally nurse every 2 to 3 hours and should not sleep more than 4 hours at a time.
- Check with your doctor, hospital emergency room, or local emergency services (eg, “call 9-1-1”) immediately if your baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, difficulty breathing, or limpness. These may be symptoms of an overdose and need immediate medical attention.
Using chlorpheniramine and codeine polistirex while you are pregnant may cause serious unwanted effects, including neonatal opioid withdrawal syndrome in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using chlorpheniramine and codeine polistirex.
Using chlorpheniramine and codeine polistirex can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.
Chlorpheniramine and codeine polistirex may make you confused, dizzy, or drowsy. Do not drive or do anything else that could be dangerous until you know how chlorpheniramine and codeine polistirex affects you.
Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.
Chlorpheniramine and codeine polistirex will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds, sedatives, tranquilizers, or sleeping medicine, other prescription pain medicine or narcotics, medicine for seizures or barbiturates, muscle relaxants, or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using chlorpheniramine and codeine polistirex.
If you think you or someone else may have taken an overdose of chlorpheniramine and codeine polistirex, get emergency help at once. Signs of an overdose include: pale or blue lips, fingernails, or skin, confusion, difficult or troubled breathing, irregular, fast or slow, or shallow breathing, extreme sleepiness or drowsiness, cold and clammy skin, or lightheadedness or fainting.
Chlorpheniramine and codeine polistirex may cause adrenal insufficiency. Check with your doctor right away if you have darkening of the skin, diarrhea, dizziness, fainting, loss of appetite, mental depression, nausea, skin rash, unusual tiredness or weakness, or vomiting.
If you are especially sensitive to the effects of chlorpheniramine and codeine polistirex, do not suddenly stop using it without first checking with your doctor Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble sleeping.
Using too much of chlorpheniramine and codeine polistirex may cause infertility (unable to have children). Talk with your doctor before using chlorpheniramine and codeine polistirex if you plan to have children.
Make sure any doctor or dentist who treats you knows that you are using chlorpheniramine and codeine polistirex.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Chlorpheniramine and codeine polistirex side effects
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Incidence not known
- Anxiety
- belching
- bloating
- blurred or loss of vision
- chills
- cold, clammy skin
- cold sweat
- confusion
- dark urine
- depression
- diarrhea
- difficult or painful urination
- disturbed color perception
- dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
- double vision
- dryness or spasm of the throat
- feeling of constant movement of self or surroundings
- fever
- halos around lights
- headache
- heartburn
- increased hunger
- indigestion
- irregular, fast or slow, or shallow breathing
- loss of appetite
- nausea
- nervousness
- night blindness
- nightmares
- overbright appearance of lights
- pain in the stomach, side, or abdomen, possibly radiating to the back
- pain or discomfort in the chest, upper stomach, or throat
- pale or blue lips, fingernails, or skin
- pressure in the stomach
- pounding in the ears
- seizures
- sensation of spinning
- shakiness
- sleepiness or unusual drowsiness
- slow, fast, or irregular heartbeat
- slurred speech
- stomach discomfort, upset, or pain
- sweating
- tunnel vision
- unusual tiredness or weakness
- vomiting
- yellow eyes or skin
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Incidence not known
- Anxiety
- blistering, crusting, or irritation of the skin
- continuing ringing or buzzing or other unexplained noise in the ears
- cracked, dry, scaly skin
- dry mouth
- early menstrual periods
- face is warm or hot to touch
- false or unusual sense of well-being
- general feeling of discomfort or illness
- hearing loss
- hiccups
- increased appetite
- increased in sexual ability, desire, drive, or performance
- increased interest in sexual intercourse
- irritability
- lack or loss of strength
- redness of the face
- restlessness
- skin rash, itching, redness, hives, swelling
- swelling of the breasts or breast soreness in both females and males
- trouble sleeping
- twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
- watering of the eyes
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Seek emergency medical attention or call 115
Further information
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Medical Disclaimer
The content of Holevn is solely for the purpose of providing information about Thuốc Chlorpheniramine and codeine polistirex (Oral) and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/cons/chlorpheniramine-and-codeine-polistirex.html
