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Tên chung: urofollitropin (pin URE oh FOL i TROE)
Tên thương hiệu: Bravelle
Được xem xét về mặt y tế bởi Holevn.org vào ngày 28 tháng 10 năm 2019 – Viết bởi Cerner Multum
Bravelle là gì?
Bravelle là một dạng tinh khiết của một loại hormone gọi là hormone kích thích nang trứng (FSH). Hormone này rất quan trọng trong sự phát triển của nang trứng (trứng) được sản xuất bởi buồng trứng ở phụ nữ.
Bravelle được sử dụng cùng với các loại thuốc khác để điều trị vô sinh ở phụ nữ bị thiếu hụt FSH. Thuốc này cũng được sử dụng để giúp buồng trứng sản xuất nhiều trứng để sử dụng trong thụ tinh “trong ống nghiệm”.
Bravelle một mình sẽ không gây rụng trứng (sản xuất trứng bởi buồng trứng). Bạn sẽ cần nhận được các loại thuốc khác để kích thích rụng trứng.
Bravelle cũng có thể được sử dụng cho các mục đích không được liệt kê trong hướng dẫn thuốc này.
Thông tin quan trọng
Bạn không nên sử dụng Bravelle nếu bạn bị suy buồng trứng nguyên phát, chảy máu âm đạo bất thường, rối loạn tuyến giáp hoặc tuyến thượng thận không kiểm soát, u nang buồng trứng, ung thư vú, ung thư tử cung hoặc buồng trứng, khối u tuyến yên hoặc vô sinh không phải do rụng trứng. .
Không sử dụng Bravelle nếu bạn đang mang thai.
Stop using Bravelle, do not have sexual intercourse, and call your doctor right away if you have any of the following symptoms: stomach pain, bloating, nausea, vomiting, diarrhea, rapid weight gain, little or no urinating, or pain when you breathe, rapid heart rate, or shortness of breath.
Before taking this medicine
You should not use this medicine if you are allergic to Bravelle or similar medicines (such as follitropin, lutropin alfa, menotropin), or if you have:
a condition called primary ovarian failure;
cancer of the breast, uterus, or ovary;
an untreated or uncontrolled disorder of your thyroid or adrenal gland;
infertility that is not caused by lack of ovulation;
abnormal vaginal bleeding that has not been checked by a doctor;
an ovarian cyst;
a tumor of your pituitary gland; or
if you are pregnant.
Your doctor will perform blood tests and a pelvic exam to make sure you do not have conditions that would prevent you from safely using Bravelle.
Your male sexual partner’s fertility should also be checked before you are treated with Bravelle.
To make sure Bravelle is safe for you, tell your doctor if you have:
a history of stomach surgery;
a history of ovarian cyst or “torsion” (twisting) of your ovary; or
risk factors for blood clots (such as diabetes, smoking, heart disease, coronary artery disease, being overweight, having a family history of coronary artery disease).
Using Bravelle can increase your chances of having a multiple pregnancy (twins, triplets, quadruplets, etc). A multiple pregnancy is a high-risk pregnancy for the mother and for the babies. Follow your doctor’s instructions about any special care you may need during your pregnancy.
Bravelle may also increase your risk of tubal pregnancy, miscarriage, stillbirth, premature labor, birth defects, or fever after childbirth if you become pregnant after being treated with this medicine. Talk with your doctor if you are concerned about these risks.
Bravelle may increase your risk of developing uterine cancer. Ask your doctor about your specific risk. Report any unusual vaginal bleeding right away.
FDA pregnancy category X. Although Bravelle can help you become pregnant, this medicine can harm an unborn baby or cause birth defects. Do not use this medicine if you are pregnant. Tell your doctor right away if you become pregnant during treatment.
It is not known whether urofollitropin passes into breast milk or if it could harm a nursing baby. You should not breast-feed while using this medicine.
How should I use Bravelle?
Follow all directions on your prescription label. Do not use Bravelle in larger or smaller amounts or for longer than recommended.
Bravelle is injected under the skin or into a muscle. You may be shown how to use injections at home. Do not self-inject this medicine if you do not understand how to give the injection and properly dispose of used needles and syringes.
This medicine comes with patient instructions for safe and effective use. Follow these directions carefully. Ask your doctor or pharmacist if you have any questions.
Bravelle is a powder medicine that must be mixed with a liquid (diluent) before using it. If you are using the injections at home, be sure you understand how to properly mix and store the medicine.
Gently swirl the medicine after mixing. Do not shake the medication bottle or you may ruin the medicine. Prepare your dose only when you are ready to give an injection. Do not use if the medicine is cloudy, has changed colors, or has particles in it. Call your pharmacist for new medicine.
After giving the injection, throw away any portion of the mixed medicine that is not used right away. Do not save it for later use.
For the best results from your fertility treatments, follow your doctor’s instructions very carefully.
Use a disposable needle and syringe only once. Follow any state or local laws about throwing away used needles and syringes. Use a puncture-proof “sharps” disposal container (ask your pharmacist where to get one and how to throw it away). Keep this container out of the reach of children and pets.
To be sure the medicine is effective, you will need frequent blood tests and ultrasound exams. You may also need to record your temperature on a daily chart.
Store unmixed powder medicine at room temperature away from moisture, heat, and light.
You may also store the powder in a refrigerator. Do not freeze.
Infertility is often treated with a combination of drugs. Use all medications as directed by your doctor. Read the medication guide or patient instructions provided with each medication. Do not change your doses or medication schedule without your doctor’s advice.
What happens if I miss a dose?
Call your doctor for instructions if you miss a dose of Bravelle.
What happens if I overdose?
Seek emergency medical attention or call 115.
What should I avoid while using Bravelle?
Follow your doctor’s instructions about any restrictions on food, beverages, or activity.
Bravelle side effects
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Some women using Bravelle develop a condition called ovarian hyperstimulation syndrome (OHSS), especially after the first treatment. OHSS can be a life threatening condition. Stop using Bravelle, do not have sexual intercourse, and call your doctor right away if you have any of the following symptoms of OHSS:
stomach pain, bloating;
nausea, vomiting, diarrhea;
rapid weight gain, especially in your face and midsection;
little or no urinating; or
pain when you breathe, rapid heart rate, feeling short of breath (especially when lying down).
Also call your doctor at once if you have signs of a stroke or blood clot, such as:
sudden numbness or weakness (especially on one side of the body), sudden severe headache, slurred speech, problems with vision or balance;
chest pain, sudden cough, wheezing, rapid breathing, coughing up blood; or
pain, swelling, warmth, or redness in one or both legs.
Common side effects may include:
stomach cramps or bloating;
headache, general pain;
hot flashes; or
mild pelvic pain, pain after an egg is removed for in-vitro fertilization.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
What other drugs will affect Bravelle?
Other drugs may interact with urofollitropin, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell each of your health care providers about all medicines you use now and any medicine you start or stop using.
Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.
Copyright 1996-2018 Cerner Multum, Inc. Version: 3.01.
The content of Holevn is solely for the purpose of providing information about Thuốc Bravelle and is not intended to be a substitute for professional medical advice, diagnosis or treatment. Please contact your nearest doctor or clinic, hospital for advice. We do not accept liability if the patient arbitrarily uses the drug without following a doctor’s prescription.
Reference from: https://www.drugs.com/mtm/bravelle.html
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